SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3we7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 12 HIS A  44
PHE A 224
HIS A 155
ASP A  47
ASP A  46
 ZN  A 301 (-3.2A)
None
ZN  A 301 ( 3.3A)
ZN  A 301 ( 2.1A)
ACY  A 303 (-3.0A)
 1.11A 1a4lA-3we7A:
2.0		 1a4lA-3we7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 12 HIS A  44
PHE A 224
HIS A 155
ASP A  47
ASP A  46
 ZN  A 301 (-3.2A)
None
ZN  A 301 ( 3.3A)
ZN  A 301 ( 2.1A)
ACY  A 303 (-3.0A)
 1.06A 1a4lC-3we7A:
undetectable		 1a4lC-3we7A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 5 THR A  72
ASP A 154
HIS A 152
HIS A  44
 None
None
GOL  A 302 (-3.9A)
ZN  A 301 (-3.2A)
 1.18A 1ei6A-3we7A:
undetectable		 1ei6A-3we7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 11 ILE A 217
GLY A  51
GLU A 253
LEU A 212
GLY A  54
 None
 1.30A 1i7qA-3we7A:
undetectable		 1i7qA-3we7A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 PRO A 225
PHE A 224
GLN A 223
VAL A 219
 None
None
GOL  A 302 ( 4.6A)
None
 1.43A 1l2iB-3we7A:
undetectable		 1l2iB-3we7A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		3 / 3 TRP A 229
PHE A 224
TRP A 232
 None
 1.17A 1r15C-3we7A:
2.4		 1r15C-3we7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		3 / 3 TRP A 229
PHE A 224
TRP A 232
 None
 1.16A 1r15F-3we7A:
2.3		 1r15F-3we7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		3 / 3 TRP A 229
PHE A 224
TRP A 232
 None
 1.17A 1r15G-3we7A:
2.4		 1r15G-3we7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		3 / 3 TRP A 229
PHE A 224
TRP A 232
 None
 1.16A 1r15H-3we7A:
2.1		 1r15H-3we7A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 8 HIS A  44
ARG A  92
ASP A 115
HIS A 152
ASP A 154
 ZN  A 301 (-3.2A)
GOL  A 302 (-3.0A)
GOL  A 302 (-2.8A)
GOL  A 302 (-3.9A)
None
 0.38A 2xadA-3we7A:
20.2		 2xadA-3we7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 8 HIS A  44
ARG A  92
ASP A 115
HIS A 152
ASP A 154
 ZN  A 301 (-3.2A)
GOL  A 302 (-3.0A)
GOL  A 302 (-2.8A)
GOL  A 302 (-3.9A)
None
 0.38A 2xadB-3we7A:
19.8		 2xadB-3we7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 8 HIS A  44
ARG A  92
ASP A 115
HIS A 152
ASP A 154
 ZN  A 301 (-3.2A)
GOL  A 302 (-3.0A)
GOL  A 302 (-2.8A)
GOL  A 302 (-3.9A)
None
 0.39A 2xadC-3we7A:
20.1		 2xadC-3we7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 8 HIS A  44
ARG A  92
ASP A 115
HIS A 152
ASP A 154
 ZN  A 301 (-3.2A)
GOL  A 302 (-3.0A)
GOL  A 302 (-2.8A)
GOL  A 302 (-3.9A)
None
 0.39A 2xadD-3we7A:
19.9		 2xadD-3we7A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		3 / 3 TYR A  68
GLU A 253
ASP A 205
 None
 0.85A 3bxoA-3we7A:
3.3		 3bxoA-3we7A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 10 VAL A 204
MET A  52
ILE A  56
VAL A  66
VAL A  38
 None
 1.08A 3fhjA-3we7A:
3.0		 3fhjA-3we7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 10 VAL A 204
MET A  52
ILE A  56
VAL A  66
VAL A  38
 None
 1.08A 3fhjB-3we7A:
4.5		 3fhjB-3we7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 10 VAL A 204
MET A  52
ILE A  56
VAL A  66
VAL A  38
 None
 1.08A 3fhjC-3we7A:
4.9		 3fhjC-3we7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 9 VAL A 204
MET A  52
ILE A  56
VAL A  66
VAL A  38
 None
 1.08A 3fhjD-3we7A:
4.0		 3fhjD-3we7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 10 VAL A 204
MET A  52
ILE A  56
VAL A  66
VAL A  38
 None
 1.08A 3fhjE-3we7A:
3.7		 3fhjE-3we7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 9 VAL A 204
MET A  52
ILE A  56
VAL A  66
VAL A  38
 None
 1.08A 3fhjF-3we7A:
4.6		 3fhjF-3we7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 12 LEU A  59
GLY A 139
LEU A 132
PRO A 137
SER A 165
 None
 1.19A 3i5uB-3we7A:
4.1		 3i5uB-3we7A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 GLN A 223
HIS A 152
HIS A 155
ASP A  46
 GOL  A 302 ( 4.6A)
GOL  A 302 (-3.9A)
ZN  A 301 ( 3.3A)
ACY  A 303 (-3.0A)
 1.09A 3nvcA-3we7A:
undetectable		 3nvcA-3we7A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 HIS A 152
GLU A  42
ASP A 115
GLU A  95
 GOL  A 302 (-3.9A)
None
GOL  A 302 (-2.8A)
None
 1.17A 3vywA-3we7A:
2.8		 3vywA-3we7A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		5 / 11 SER A 165
SER A 169
ILE A  41
VAL A 140
LEU A  39
 None
 1.08A 3w67A-3we7A:
undetectable		 3w67A-3we7A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.93A 3wg7N-3we7A:
undetectable
3wg7W-3we7A:
undetectable		 3wg7N-3we7A:
18.46
3wg7W-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 228
GLN A 223
ILE A  50
ASP A  47
 None
GOL  A 302 ( 4.6A)
None
ZN  A 301 ( 2.1A)
 1.11A 4w5qA-3we7A:
2.4		 4w5qA-3we7A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 228
GLN A 223
ILE A  50
ASP A  47
 None
GOL  A 302 ( 4.6A)
None
ZN  A 301 ( 2.1A)
 1.06A 4w5tA-3we7A:
2.4		 4w5tA-3we7A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 228
GLN A 223
ILE A  50
ASP A  47
 None
GOL  A 302 ( 4.6A)
None
ZN  A 301 ( 2.1A)
 1.16A 4z4dA-3we7A:
2.8		 4z4dA-3we7A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.75A 5b1aA-3we7A:
undetectable
5b1aJ-3we7A:
undetectable		 5b1aA-3we7A:
18.46
5b1aJ-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.88A 5b1bA-3we7A:
undetectable
5b1bJ-3we7A:
undetectable		 5b1bA-3we7A:
18.46
5b1bJ-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.81A 5b1bN-3we7A:
undetectable
5b1bW-3we7A:
undetectable		 5b1bN-3we7A:
18.46
5b1bW-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.75A 5b3sA-3we7A:
undetectable
5b3sJ-3we7A:
undetectable		 5b3sA-3we7A:
18.46
5b3sJ-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.91A 5b3sN-3we7A:
undetectable
5b3sW-3we7A:
undetectable		 5b3sN-3we7A:
18.46
5b3sW-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.93A 5z86N-3we7A:
undetectable
5z86W-3we7A:
undetectable		 5z86N-3we7A:
18.46
5z86W-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 8 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.77A 5zcoA-3we7A:
undetectable
5zcoJ-3we7A:
undetectable		 5zcoA-3we7A:
18.46
5zcoJ-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.96A 5zcoN-3we7A:
undetectable
5zcoW-3we7A:
undetectable		 5zcoN-3we7A:
18.46
5zcoW-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.79A 5zcpA-3we7A:
undetectable
5zcpJ-3we7A:
undetectable		 5zcpA-3we7A:
18.46
5zcpJ-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 7 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.79A 5zcqA-3we7A:
undetectable
5zcqJ-3we7A:
undetectable		 5zcqA-3we7A:
18.46
5zcqJ-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 8 ILE A 192
ARG A 125
THR A 129
LEU A 132
 None
 0.83A 5zcqN-3we7A:
undetectable
5zcqW-3we7A:
undetectable		 5zcqN-3we7A:
18.46
5zcqW-3we7A:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 3we7 PUTATIVE
UNCHARACTERIZED
PROTEIN PH0499
(Pyrococcus
horikoshii) 		4 / 6 ILE A 228
GLN A 223
ILE A  50
ASP A  47
 None
GOL  A 302 ( 4.6A)
None
ZN  A 301 ( 2.1A)
 1.03A 6cbdA-3we7A:
2.2		 6cbdA-3we7A:
17.03