SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wea'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		4 / 7 PRO A  44
THR A 123
ILE A 122
GLY A  11
 None
 0.77A 1usqA-3weaA:
undetectable		 1usqA-3weaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		4 / 7 PRO A  44
THR A 123
ILE A 122
GLY A  11
 None
 0.77A 1usqF-3weaA:
undetectable		 1usqF-3weaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		4 / 7 PRO A  44
THR A 123
ILE A 122
GLY A  11
 None
 0.83A 2jkjE-3weaA:
undetectable		 2jkjE-3weaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		4 / 7 PRO A  44
THR A 123
ILE A 122
GLY A  11
 None
 0.83A 2jklD-3weaA:
undetectable		 2jklD-3weaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		4 / 7 PRO A  44
THR A 123
ILE A 122
GLY A  11
 None
 0.83A 2jklE-3weaA:
undetectable		 2jklE-3weaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		4 / 7 PRO A  44
THR A 123
ILE A 122
GLY A  11
 None
 0.83A 2jklF-3weaA:
undetectable		 2jklF-3weaA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3wea NIEMANN-PICK TYPE C2
PROTEIN
(Camponotus
japonicus) 		5 / 12 LEU A  68
LEU A 108
PHE A 127
VAL A  38
VAL A  95
 None
 1.15A 2ygpA-3weaA:
undetectable		 2ygpA-3weaA:
21.76