SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wel'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 ILE A 286
ASN A 270
ASN A 522
THR A 519
 None
GOL  A1010 ( 4.0A)
GOL  A1010 (-3.0A)
None
 1.17A 1h7xA-3welA:
7.3		 1h7xA-3welA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 ILE A 286
ASN A 270
ASN A 522
THR A 519
 None
GOL  A1010 ( 4.0A)
GOL  A1010 (-3.0A)
None
 1.18A 1h7xC-3welA:
10.3		 1h7xC-3welA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 ILE A 286
ASN A 270
ASN A 522
THR A 519
 None
GOL  A1010 ( 4.0A)
GOL  A1010 (-3.0A)
None
 1.17A 1h7xD-3welA:
8.2		 1h7xD-3welA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 10 ASN A 496
ILE A 494
GLY A 271
GLU A 472
GLY A 244
 None
 1.14A 1mehA-3welA:
4.7		 1mehA-3welA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 GLY A 211
ASN A 241
LEU A 242
LEU A 210
GLY A 587
 None
 1.04A 2f8lA-3welA:
undetectable		 2f8lA-3welA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 PHE A 476
TRP A 432
TYR A 438
GLY A 429
 None
ACR  A1001 ( 4.6A)
None
None
 0.93A 2gssA-3welA:
undetectable		 2gssA-3welA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 PHE A 476
TRP A 432
TYR A 438
GLY A 429
 None
ACR  A1001 ( 4.6A)
None
None
 0.92A 2gssB-3welA:
undetectable		 2gssB-3welA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HCJ_B_TACB888_1
(PROTEIN CHAIN
ELONGATION FACTOR
EF-TU)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 THR A 511
SER A 485
ASP A 488
PRO A 483
 None
 1.41A 2hcjA-3welA:
0.0
2hcjB-3welA:
0.0		 2hcjA-3welA:
4.29
2hcjB-3welA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_B_017B203_1
(PROTEASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 TRP A 320
LEU A 351
ARG A 392
GLY A 390
 None
 1.21A 2hs2B-3welA:
undetectable		 2hs2B-3welA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKC_A_TRPA1520_0
(FLAVIN-DEPENDENT
TRYPTOPHAN
HALOGENASE PRNA)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 10 ILE A 106
PRO A 107
ILE A 289
PHE A 555
ASN A 270
 None
None
None
None
GOL  A1010 ( 4.0A)
 1.37A 2jkcA-3welA:
0.0		 2jkcA-3welA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_1
(PROTEASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 LEU A 154
ALA A  84
ILE A 164
ILE A 294
ILE A 290
 None
 1.00A 2o4nA-3welA:
undetectable		 2o4nA-3welA:
7.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASN A 237
ASP A 469
ARG A 552
ASP A 568
ALA A 570
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
None
 1.20A 2qmjA-3welA:
51.8		 2qmjA-3welA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 ASP A 232
ASN A 237
ASP A 357
ILE A 358
ILE A 396
ASP A 469
ARG A 552
ASP A 568
PHE A 601
ALA A 602
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 ( 4.4A)
ACR  A1001 (-4.1A)
 0.68A 2qmjA-3welA:
51.8		 2qmjA-3welA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 ASP A 232
ASP A 357
ILE A 358
ILE A 396
TRP A 432
ASP A 469
ARG A 552
ASP A 568
PHE A 601
ALA A 602
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 ( 4.4A)
ACR  A1001 (-4.1A)
 0.31A 2qmjA-3welA:
51.8		 2qmjA-3welA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 568
ASP A 398
ILE A 396
ILE A 358
ASP A 232
 ACR  A1001 (-2.7A)
None
ACR  A1001 (-4.9A)
ACR  A1001 (-3.6A)
ACR  A1001 (-2.7A)
 1.13A 2qmjA-3welA:
51.8		 2qmjA-3welA:
36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 ILE A 164
ALA A 176
ILE A  94
PHE A 152
 None
 0.79A 2w9sE-3welA:
undetectable		 2w9sE-3welA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 232
ASP A 357
ASP A 469
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.2A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.41A 2x2iA-3welA:
3.9		 2x2iA-3welA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 TRP A 467
MET A 470
ARG A 552
TRP A 565
 None
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
 0.66A 2x2iA-3welA:
32.8		 2x2iA-3welA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 232
ASP A 357
ASP A 469
MET A 470
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.46A 2x2iB-3welA:
37.6		 2x2iB-3welA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 232
ASP A 357
ASP A 469
MET A 470
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.42A 2x2iC-3welA:
35.4		 2x2iC-3welA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 232
ASP A 357
ASP A 469
MET A 470
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.41A 2x2iD-3welA:
38.3		 2x2iD-3welA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 LEU A 779
ILE A 848
LEU A 851
ILE A 846
MET A 783
 None
 1.12A 2ygpA-3welA:
undetectable		 2ygpA-3welA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 7 PHE A 476
GLY A 429
ASP A 398
TYR A 438
 None
 0.94A 3aruA-3welA:
10.5		 3aruA-3welA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 SER A 144
PHE A  86
VAL A 142
ALA A  84
 None
 1.00A 3ax7A-3welA:
undetectable		 3ax7A-3welA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 9 PRO A 433
VAL A 436
GLY A 429
ILE A 508
GLY A 400
 None
 1.30A 3csjB-3welA:
undetectable		 3csjB-3welA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 ASP A 443
ALA A 446
GLY A 413
PRO A 426
 None
 0.77A 3el9A-3welA:
undetectable		 3el9A-3welA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 7 THR A 163
VAL A 151
THR A 153
VAL A 142
 None
 0.30A 3em0B-3welA:
2.5		 3em0B-3welA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 PRO A 776
THR A 775
GLY A 651
THR A 648
 None
 1.07A 3ib1A-3welA:
undetectable		 3ib1A-3welA:
16.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 ASP A 357
ILE A 358
ILE A 396
TRP A 432
TRP A 467
ASP A 469
MET A 470
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.53A 3l4wA-3welA:
49.3		 3l4wA-3welA:
36.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 GLY A 465
TRP A 355
VAL A 353
 None
 0.60A 3n62B-3welA:
undetectable		 3n62B-3welA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 GLY A 465
TRP A 355
VAL A 353
 None
 0.63A 3n65B-3welA:
undetectable		 3n65B-3welA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 GLY A 465
TRP A 355
VAL A 353
 None
 0.59A 3n66B-3welA:
undetectable		 3n66B-3welA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 PHE A 476
TRP A 432
TYR A 438
GLY A 429
 None
ACR  A1001 ( 4.6A)
None
None
 0.91A 3n9jA-3welA:
undetectable		 3n9jA-3welA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 9 ILE A  96
PHE A  79
ASN A  49
ALA A  62
VAL A  47
 None
 1.17A 3o01A-3welA:
undetectable
3o01B-3welA:
undetectable		 3o01A-3welA:
16.30
3o01B-3welA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 232
ASP A 357
ILE A 358
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.50A 3phaA-3welA:
42.1		 3phaA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 ASP A 232
ASP A 357
ILE A 358
ILE A 396
TRP A 432
ASP A 469
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.37A 3phaA-3welA:
42.1		 3phaA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 568
ASP A 398
ILE A 396
ILE A 358
ASP A 232
 ACR  A1001 (-2.7A)
None
ACR  A1001 (-4.9A)
ACR  A1001 (-3.6A)
ACR  A1001 (-2.7A)
 1.13A 3phaA-3welA:
42.1		 3phaA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ASP A 357
ILE A 358
ILE A 396
TRP A 432
ASP A 469
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.32A 3phaB-3welA:
32.4		 3phaB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 568
ASP A 398
ILE A 396
ILE A 358
ASP A 232
 ACR  A1001 (-2.7A)
None
ACR  A1001 (-4.9A)
ACR  A1001 (-3.6A)
ACR  A1001 (-2.7A)
 1.14A 3phaB-3welA:
32.4		 3phaB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ASP A 357
ILE A 358
TRP A 432
ASP A 469
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.35A 3phaC-3welA:
36.0		 3phaC-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 232
ASP A 357
ILE A 396
ARG A 552
ASP A 568
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.36A 3phaC-3welA:
36.0		 3phaC-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ASP A 357
ILE A 358
TRP A 432
ASP A 469
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.29A 3phaD-3welA:
36.2		 3phaD-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 232
ASP A 357
ILE A 396
MET A 470
ASP A 568
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.40A 3phaD-3welA:
36.2		 3phaD-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 357
ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.41A 3pocA-3welA:
36.5		 3pocA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 432
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.40A 3pocA-3welA:
36.5		 3pocA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.85A 3pocA-3welA:
36.5		 3pocA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 357
ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.49A 3pocB-3welA:
40.3		 3pocB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 432
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.38A 3pocB-3welA:
40.3		 3pocB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.88A 3pocB-3welA:
40.3		 3pocB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 10 ILE A 311
ALA A 556
ILE A 281
TYR A 283
ILE A 286
 None
 1.13A 3prsA-3welA:
undetectable		 3prsA-3welA:
17.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ASP A 357
ILE A 396
TRP A 432
ASP A 469
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.36A 3topA-3welA:
45.0		 3topA-3welA:
34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 232
TRP A 432
MET A 470
ASP A 568
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.47A 3topA-3welA:
45.0		 3topA-3welA:
34.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ASP A 357
ILE A 396
TRP A 432
ASP A 469
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.36A 3topB-3welA:
45.1		 3topB-3welA:
34.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 THR A 562
GLY A 244
ALA A 596
GLY A 595
ASN A 569
 None
 1.19A 3v3oA-3welA:
undetectable		 3v3oA-3welA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 LEU A 897
MET A 843
ASP A 893
 None
 0.81A 3v5wA-3welA:
undetectable		 3v5wA-3welA:
21.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 ASP A 232
ALA A 234
ASN A 237
ASP A 357
ILE A 358
MET A 470
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.43A 3w37A-3welA:
66.6		 3w37A-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		12 / 12 ASP A 232
ALA A 234
ASN A 237
ASP A 357
ILE A 396
TRP A 467
ASP A 469
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.10A 3w37A-3welA:
66.6		 3w37A-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 5 PHE A 236
TRP A 329
ILE A 358
TRP A 432
TRP A 565
 ACR  A1001 (-4.9A)
ACR  A1001 (-4.1A)
ACR  A1001 (-3.6A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-4.8A)
 0.17A 3w37A-3welA:
66.6		 3w37A-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		12 / 12 ASP A 232
ALA A 234
PHE A 236
ASN A 237
ASP A 357
ILE A 358
ASP A 469
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.16A 3wemA-3welA:
62.2		 3wemA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 ASP A 232
ALA A 234
PHE A 236
ASN A 237
ASP A 357
ILE A 396
MET A 470
ASP A 568
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.41A 3wemA-3welA:
62.2		 3wemA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEM_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 5 ILE A 233
TRP A 329
TRP A 432
TRP A 467
TRP A 565
 GLC  A1002 (-3.9A)
ACR  A1001 (-4.1A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
 0.29A 3wemA-3welA:
62.2		 3wemA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		12 / 12 ASP A 232
ALA A 234
ASN A 237
ASP A 357
ILE A 358
TRP A 467
ASP A 469
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.16A 3wenA-3welA:
65.7		 3wenA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 ASP A 232
ALA A 234
ASN A 237
ASP A 357
ILE A 396
MET A 470
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.45A 3wenA-3welA:
65.7		 3wenA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEN_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 ILE A 233
TRP A 329
TRP A 432
TRP A 565
 GLC  A1002 (-3.9A)
ACR  A1001 (-4.1A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-4.8A)
 0.32A 3wenA-3welA:
65.7		 3wenA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		12 / 12 ASP A 232
ALA A 234
PHE A 236
ASN A 237
ASP A 357
ILE A 358
TRP A 467
ASP A 469
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.06A 3weoA-3welA:
62.1		 3weoA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 ASP A 232
ALA A 234
PHE A 236
ASN A 237
ASP A 357
ILE A 396
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.38A 3weoA-3welA:
62.1		 3weoA-3welA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 6 ILE A 233
TRP A 329
ILE A 396
TRP A 432
MET A 470
TRP A 565
 GLC  A1002 (-3.9A)
ACR  A1001 (-4.1A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-4.8A)
 0.11A 3weoA-3welA:
62.1		 3weoA-3welA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 8 ASP A 273
TYR A 283
HIS A 222
LEU A 228
 None
 1.21A 3x2qA-3welA:
undetectable
3x2qC-3welA:
undetectable
3x2qP-3welA:
undetectable		 3x2qA-3welA:
20.07
3x2qC-3welA:
15.33
3x2qP-3welA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 357
ILE A 358
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.30A 4b9zA-3welA:
38.4		 4b9zA-3welA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 357
ILE A 396
ASP A 469
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.28A 4b9zA-3welA:
38.4		 4b9zA-3welA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 357
ILE A 396
ASP A 469
GLU A 472
ARG A 552
ASP A 568
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
None
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.1A)
 1.50A 4b9zA-3welA:
38.4		 4b9zA-3welA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 ARG A 629
ARG A 328
TRP A 329
 None
None
ACR  A1001 (-4.1A)
 0.94A 4cpzC-3welA:
undetectable		 4cpzC-3welA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 ARG A 629
ARG A 328
TRP A 329
 None
None
ACR  A1001 (-4.1A)
 1.02A 4cpzE-3welA:
undetectable		 4cpzE-3welA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 ARG A 629
ARG A 328
TRP A 329
 None
None
ACR  A1001 (-4.1A)
 0.90A 4cpzH-3welA:
undetectable		 4cpzH-3welA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 5 ARG A 612
VAL A 714
LEU A 743
SER A 713
 None
 1.25A 4e1gA-3welA:
undetectable		 4e1gA-3welA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 7 PHE A 441
TYR A 527
ILE A 508
PRO A 439
 None
 1.19A 4g5jA-3welA:
undetectable		 4g5jA-3welA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 TYR A 527
ALA A 512
TYR A 427
ILE A 477
GLY A 400
 None
 1.31A 4iilA-3welA:
undetectable		 4iilA-3welA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 9 THR A 141
LEU A 154
ALA A  50
LEU A  63
GLN A  65
 None
 1.30A 4ltwA-3welA:
undetectable		 4ltwA-3welA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 THR A 847
LEU A 656
LEU A 793
GLU A 792
 None
 0.72A 4nc3A-3welA:
undetectable		 4nc3A-3welA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 PHE A 815
THR A 775
LEU A 795
 None
 0.73A 4qztA-3welA:
1.6		 4qztA-3welA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 ASN A 758
LEU A 656
PHE A 724
TYR A 729
 None
None
None
GOL  A1009 (-3.6A)
 1.31A 4u14A-3welA:
undetectable		 4u14A-3welA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 ASP A 575
ARG A 572
TYR A 578
 None
 0.98A 5a7mA-3welA:
2.5		 5a7mA-3welA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 ASP A 575
ARG A 572
TYR A 578
 None
 0.96A 5a7mB-3welA:
3.2		 5a7mB-3welA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 TYR A 527
ALA A 523
PHE A 555
SER A 245
GLU A 531
 None
 1.50A 5cprB-3welA:
undetectable		 5cprB-3welA:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 LEU A 549
ARG A 458
ILE A 466
ILE A 463
 None
 1.24A 5dzk2-3welA:
undetectable
5dzkM-3welA:
undetectable
5dzkN-3welA:
undetectable		 5dzk2-3welA:
3.12
5dzkM-3welA:
12.60
5dzkN-3welA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 ILE A 466
ILE A 463
ARG A 458
LEU A 549
 None
 1.36A 5dzkh-3welA:
undetectable
5dzkn-3welA:
undetectable
5dzkv-3welA:
undetectable		 5dzkh-3welA:
12.60
5dzkn-3welA:
12.60
5dzkv-3welA:
3.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 GLY A 271
GLY A 287
ILE A 503
ASN A 496
LEU A 526
 None
GOL  A1010 (-3.5A)
None
None
None
 1.04A 5fa8A-3welA:
undetectable		 5fa8A-3welA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_A_REAA602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ILE A 311
GLY A 559
THR A 562
ASN A 525
PHE A 555
 None
 1.49A 5fhzA-3welA:
undetectable		 5fhzA-3welA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 467
ASP A 469
MET A 470
PHE A 476
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
None
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.45A 5iefA-3welA:
41.2		 5iefA-3welA:
29.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 ARG A 552
TRP A 565
ASP A 597
ARG A 624
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
None
None
 0.19A 5iefA-3welA:
41.2		 5iefA-3welA:
29.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 10 TYR A 283
ILE A 281
VAL A 303
ILE A 294
PRO A 300
LEU A 196
 None
 1.46A 5ienB-3welA:
1.3		 5ienB-3welA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 9 MET A 783
VAL A 781
LEU A 779
ILE A 846
LEU A 812
 None
 1.31A 5iepA-3welA:
undetectable		 5iepA-3welA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 GLY A 429
TYR A 427
GLY A 400
ASN A 475
 None
 0.85A 5k4pA-3welA:
undetectable		 5k4pA-3welA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 PHE A 902
LEU A 793
PHE A 777
ILE A 759
LEU A 906
 None
 1.28A 5ljbA-3welA:
2.2		 5ljbA-3welA:
8.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 TRP A 329
ASP A 357
ILE A 396
TRP A 432
TRP A 467
ASP A 469
MET A 470
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.69A 5nn6A-3welA:
59.8		 5nn6A-3welA:
37.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 232
ASP A 357
ILE A 358
ASP A 568
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.45A 5nn8A-3welA:
47.9		 5nn8A-3welA:
37.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ASP A 357
ILE A 396
TRP A 432
TRP A 467
ASP A 469
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.26A 5nn8A-3welA:
47.9		 5nn8A-3welA:
37.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHG_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 LEU A 187
ASP A 191
ARG A 103
ASN A 268
ILE A 289
 None
GOL  A1010 (-2.9A)
GOL  A1010 ( 4.5A)
None
None
 1.35A 5uhgC-3welA:
1.4		 5uhgC-3welA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 PHE A 619
ILE A 750
PHE A 727
ALA A 644
ILE A 349
 None
 0.94A 5vceA-3welA:
undetectable		 5vceA-3welA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 7 PRO A 509
ILE A 508
SER A 485
THR A 482
 None
 1.00A 5vkqA-3welA:
undetectable
5vkqD-3welA:
undetectable		 5vkqA-3welA:
20.29
5vkqD-3welA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 GLY A 465
TRP A 355
VAL A 353
 None
 0.62A 5vuoB-3welA:
undetectable		 5vuoB-3welA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 5 TYR A 620
MET A 583
THR A 582
LEU A 584
 None
 1.24A 5x1bJ-3welA:
undetectable		 5x1bJ-3welA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 5 TYR A 620
MET A 583
THR A 582
LEU A 584
 None
 1.24A 5x1fW-3welA:
undetectable		 5x1fW-3welA:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 10 TRP A 467
ASP A 469
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 None
ACR  A1001 (-3.2A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.57A 5x7pA-3welA:
18.7		 5x7pA-3welA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 PHE A 295
ASP A 305
LYS A 309
 None
 0.87A 6awtD-3welA:
undetectable		 6awtD-3welA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 4 PHE A 295
ASP A 305
LEU A 310
LYS A 309
 None
 1.18A 6awvA-3welA:
undetectable		 6awvA-3welA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 VAL A 274
LEU A 111
THR A 554
GLY A 244
MET A 591
 None
 1.24A 6brdA-3welA:
undetectable		 6brdA-3welA:
6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 232
ILE A 396
MET A 470
ARG A 552
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.20A 6c9xA-3welA:
37.5		 6c9xA-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 ASP A 232
TRP A 329
ILE A 358
ILE A 396
TRP A 432
ASP A 469
MET A 470
ARG A 552
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-4.1A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.42A 6c9xA-3welA:
37.5		 6c9xA-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		8 / 12 TRP A 329
ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.87A 6c9xA-3welA:
37.5		 6c9xA-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 232
ILE A 358
MET A 470
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.43A 6c9xB-3welA:
42.3		 6c9xB-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 232
ILE A 396
MET A 470
ARG A 552
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.3A)
 1.03A 6c9xB-3welA:
42.3		 6c9xB-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 ASP A 232
TRP A 329
ILE A 358
ILE A 396
TRP A 432
ASP A 469
MET A 470
ARG A 552
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-4.1A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.43A 6c9xB-3welA:
42.3		 6c9xB-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		8 / 12 TRP A 329
ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.87A 6c9xB-3welA:
42.3		 6c9xB-3welA:
26.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ILE A 358
ILE A 396
TRP A 432
ASP A 469
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.36A 6c9zA-3welA:
35.9		 6c9zA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.96A 6c9zA-3welA:
35.9		 6c9zA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ILE A 358
MET A 470
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.43A 6c9zA-3welA:
35.9		 6c9zA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
 ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 0.89A 6c9zA-3welA:
35.9		 6c9zA-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 232
ILE A 358
ILE A 396
TRP A 432
ASP A 469
MET A 470
ARG A 552
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.39A 6c9zB-3welA:
37.4		 6c9zB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 232
ILE A 358
MET A 470
PHE A 601
HIS A 626
 ACR  A1001 (-2.7A)
ACR  A1001 (-3.6A)
ACR  A1001 (-3.3A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.38A 6c9zB-3welA:
37.4		 6c9zB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 12 ASP A 232
ILE A 396
MET A 470
ARG A 552
PHE A 601
 ACR  A1001 (-2.7A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.3A)
 0.98A 6c9zB-3welA:
37.4		 6c9zB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.94A 6c9zB-3welA:
37.4		 6c9zB-3welA:
26.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 357
ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.40A 6ca1A-3welA:
36.4		 6ca1A-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
ASP A 469
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.45A 6ca1A-3welA:
36.4		 6ca1A-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		8 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.85A 6ca1A-3welA:
36.4		 6ca1A-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 357
ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.48A 6ca1B-3welA:
37.7		 6ca1B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		11 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
ASP A 469
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.41A 6ca1B-3welA:
37.7		 6ca1B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		8 / 12 TRP A 329
ASP A 357
ILE A 358
ILE A 396
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-4.1A)
ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.84A 6ca1B-3welA:
37.7		 6ca1B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 357
ILE A 358
ILE A 396
ASP A 469
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.40A 6ca3A-3welA:
37.4		 6ca3A-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		7 / 12 ASP A 357
ILE A 358
ILE A 396
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.92A 6ca3A-3welA:
37.4		 6ca3A-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 357
ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.44A 6ca3A-3welA:
37.4		 6ca3A-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		10 / 12 ASP A 357
ILE A 358
ILE A 396
ASP A 469
MET A 470
ARG A 552
TRP A 565
ASP A 568
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-4.8A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.40A 6ca3B-3welA:
37.1		 6ca3B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		9 / 12 ASP A 357
ILE A 358
ILE A 396
TRP A 432
ASP A 469
MET A 470
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
ACR  A1001 (-3.2A)
ACR  A1001 (-3.3A)
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 0.67A 6ca3B-3welA:
37.1		 6ca3B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		8 / 12 ASP A 357
ILE A 358
ILE A 396
TRP A 432
TRP A 467
TRP A 565
PHE A 601
HIS A 626
 ACR  A1001 (-3.0A)
ACR  A1001 (-3.6A)
ACR  A1001 (-4.9A)
ACR  A1001 ( 4.6A)
None
ACR  A1001 (-4.8A)
ACR  A1001 (-4.3A)
ACR  A1001 (-4.1A)
 1.13A 6ca3B-3welA:
37.1		 6ca3B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		6 / 12 ASP A 357
ILE A 396
MET A 470
ARG A 552
ASP A 568
PHE A 601
 ACR  A1001 (-3.0A)
ACR  A1001 (-4.9A)
ACR  A1001 (-3.3A)
ACR  A1001 (-3.0A)
ACR  A1001 (-2.7A)
ACR  A1001 (-4.3A)
 1.44A 6ca3B-3welA:
37.1		 6ca3B-3welA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 SER A 731
SER A 725
ALA A 745
 None
 0.53A 6dwnC-3welA:
undetectable		 6dwnC-3welA:
7.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		3 / 3 ALA A 646
PHE A 324
GLN A 326
 None
 0.72A 6eceA-3welA:
undetectable		 6eceA-3welA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		5 / 11 ASP A 575
ASN A 237
THR A 566
GLY A 567
GLU A 472
 None
ACR  A1001 (-3.0A)
None
None
None
 1.49A 6mb5A-3welA:
undetectable		 6mb5A-3welA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 6 MET A 361
THR A 368
LEU A 369
THR A 409
 None
 1.00A 6mvxA-3welA:
undetectable
6mvxB-3welA:
undetectable
6mvxC-3welA:
undetectable		 6mvxA-3welA:
16.87
6mvxB-3welA:
16.87
6mvxC-3welA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wel ALPHA-GLUCOSIDASE
(Beta
vulgaris) 		4 / 5 TYR A 620
MET A 583
THR A 582
LEU A 584
 None
 1.25A 6nknW-3welA:
undetectable		 6nknW-3welA:
6.05