SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 VAL A 144
VAL A  87
TRP A  85
 None
 0.96A 1av2A-3wevA:
undetectable
1av2B-3wevA:
undetectable		 1av2A-3wevA:
2.08
1av2B-3wevA:
2.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E71_M_ASCM995_0
(MYROSINASE MA1)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 7 GLN A 608
ARG A 614
PHE A 679
PHE A 657
 None
 0.98A 1e71M-3wevA:
undetectable		 1e71M-3wevA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 7 GLN A 608
ARG A 614
PHE A 679
PHE A 657
 None
 1.01A 1e72M-3wevA:
undetectable		 1e72M-3wevA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 8 SER A 383
PRO A 449
TYR A 114
VAL A 119
 None
LYS  A 801 (-4.4A)
None
None
 1.08A 1fduB-3wevA:
undetectable		 1fduB-3wevA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 8 PHE A 251
ARG A 633
LEU A  32
VAL A  23
 None
 0.93A 1gsfC-3wevA:
undetectable		 1gsfC-3wevA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 ASP A 500
LYS A  93
ARG A 122
 None
None
SO4  A 802 (-3.8A)
 0.82A 1ra8A-3wevA:
undetectable		 1ra8A-3wevA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 12 PRO A 249
GLY A 197
GLY A 198
GLY A  15
PHE A  63
 None
 1.12A 1wg8B-3wevA:
undetectable		 1wg8B-3wevA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_1
(CES1 PROTEIN)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 12 PHE A 179
GLY A 198
GLY A 197
SER A 222
LEU A 139
 None
 0.93A 1ya4C-3wevA:
undetectable		 1ya4C-3wevA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 7 TYR A 291
THR A 408
VAL A 270
ASP A 298
 None
 0.90A 2cppA-3wevA:
undetectable		 2cppA-3wevA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 LYS A 582
GLY A 450
PRO A 449
 TRQ  A 581 ( 2.7A)
TRQ  A 581 ( 3.3A)
LYS  A 801 (-4.4A)
 1.02A 2hreB-3wevA:
undetectable		 2hreB-3wevA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 GLN A  61
LYS A  64
VAL A   5
 None
 0.92A 2jfaB-3wevA:
undetectable		 2jfaB-3wevA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 9 ARG A 122
LEU A 172
ALA A 202
GLU A  98
GLY A 213
 SO4  A 802 (-3.8A)
None
None
SO4  A 802 (-3.7A)
None
 1.06A 2v0mB-3wevA:
undetectable		 2v0mB-3wevA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 12 LEU A 102
SER A 387
ASN A 529
PRO A 449
SER A 381
 None
None
None
LYS  A 801 (-4.4A)
None
 1.21A 2xpwA-3wevA:
undetectable		 2xpwA-3wevA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 7 ARG A 650
PHE A 251
PHE A 513
ILE A  56
 None
 1.24A 2zseA-3wevA:
undetectable		 2zseA-3wevA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_2
(PHOSPHOLIPASE A2)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 9 VAL A  87
VAL A 226
GLY A 224
PRO A 498
GLY A 140
 None
 1.45A 3bjwG-3wevA:
undetectable		 3bjwG-3wevA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 7 GLY A 482
HIS A  88
ASP A 138
ILE A 136
 None
 0.90A 3fi0P-3wevA:
undetectable		 3fi0P-3wevA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 8 TYR A 612
PHE A 513
SER A 248
ILE A 451
 None
 1.03A 3jz0B-3wevA:
undetectable		 3jz0B-3wevA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 8 SER A 381
GLN A 361
PHE A 402
ASN A 380
 None
None
None
TRQ  A 581 ( 4.8A)
 1.19A 3n66B-3wevA:
undetectable		 3n66B-3wevA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		6 / 12 ASP A 219
ASP A 138
GLY A 140
GLY A 224
ASP A 223
ILE A 153
 None
 1.32A 3prsA-3wevA:
undetectable		 3prsA-3wevA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		6 / 12 ILE A 136
ASP A 138
GLY A 140
GLY A 224
ASP A 223
ILE A 153
 None
 1.10A 3tneA-3wevA:
undetectable		 3tneA-3wevA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		6 / 12 ILE A 136
ASP A 138
GLY A 140
GLY A 224
ASP A 223
ILE A 153
 None
 1.12A 3tneB-3wevA:
undetectable		 3tneB-3wevA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 GLN A 325
PHE A 326
TYR A 328
 None
 0.98A 3ucjB-3wevA:
undetectable		 3ucjB-3wevA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 SER A 438
ASP A 263
ASP A 298
 None
 0.85A 3uj7A-3wevA:
undetectable		 3uj7A-3wevA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 4 PRO A  42
LEU A  24
ILE A 194
ARG A 186
 None
 1.37A 3w1wA-3wevA:
undetectable		 3w1wA-3wevA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 ASN A  48
GLU A 649
ARG A 633
 None
 0.91A 3wxoA-3wevA:
undetectable		 3wxoA-3wevA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 8 TYR A 291
THR A 408
VAL A 270
ASP A 298
 None
 0.92A 4l4aA-3wevA:
undetectable		 4l4aA-3wevA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 ASP A  51
VAL A  47
ASN A 651
 EDO  A 807 (-4.8A)
None
None
 0.81A 4lmnA-3wevA:
undetectable		 4lmnA-3wevA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 ASP A 435
TRP A  85
SER A   4
 None
 0.91A 4lrhB-3wevA:
undetectable		 4lrhB-3wevA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		3 / 3 ASP A 435
TRP A  85
SER A   4
 None
 0.92A 4lrhF-3wevA:
undetectable		 4lrhF-3wevA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 10 VAL A 431
TYR A 429
GLY A 269
ASP A 433
THR A 436
 None
 1.21A 4mm7A-3wevA:
undetectable		 4mm7A-3wevA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 12 LEU A 196
GLY A 198
VAL A  11
MET A 244
ILE A  56
 None
 1.29A 4oktA-3wevA:
undetectable		 4oktA-3wevA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		5 / 12 ILE A  83
GLY A 191
THR A 187
ASP A 188
VAL A   5
 None
 1.17A 5hw4C-3wevA:
undetectable		 5hw4C-3wevA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 8 PHE A 321
ILE A 306
PHE A 346
PRO A 446
 None
None
None
TRQ  A 581 ( 3.6A)
 1.09A 5x23A-3wevA:
undetectable		 5x23A-3wevA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 6 GLN A 584
ASN A 441
VAL A 443
LEU A 445
 None
None
TRQ  A 581 ( 4.6A)
None
 1.24A 5xdhA-3wevA:
undetectable
5xdhC-3wevA:
undetectable		 5xdhA-3wevA:
8.54
5xdhC-3wevA:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 6 PHE A 346
ARG A 347
LEU A 405
GLN A 361
 None
 1.02A 6b89B-3wevA:
undetectable		 6b89B-3wevA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 5 GLN A  61
VAL A 195
PRO A   7
THR A  86
 None
 1.32A 6cduA-3wevA:
undetectable
6cduB-3wevA:
undetectable		 6cduA-3wevA:
19.50
6cduB-3wevA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3wev L-LYSINE 6-OXIDASE
(Marinomonas
mediterranea) 		4 / 5 GLN A  61
VAL A 195
PRO A   7
THR A  86
 None
 1.29A 6cduI-3wevA:
undetectable
6cduJ-3wevA:
undetectable		 6cduI-3wevA:
19.50
6cduJ-3wevA:
19.50