SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wfh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NYA_A_JTZA1203_1 (BETA-2 ADRENERGIC RECEPTOR, LYSOZYME)	3wfh	MAB FAB H FRAGMENT (Mus musculus)	5 / 12	VAL A 167 VAL A 185 SER A 183 ASN A 200 ASN A 159	None	1.43A	3nyaA-3wfhA: undetectable	3nyaA-3wfhA: 18.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3WHX_B_XPGB301_1 (MAB FAB H FRAGMENT MAB FAB L FRAGMENT)	3wfh	MAB FAB H FRAGMENT (Mus musculus)	8 / 12	PHE A 33 HIS A 35 VAL A 37 TRP A 50 HIS A 99 TYR A 101 PRO A 105 TRP A 107	None	0.10A	3whxA-3wfhA: 31.4 3whxB-3wfhA: 19.1	3whxA-3wfhA: 100.00 3whxB-3wfhA: 26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	3wfh	MAB FAB H FRAGMENT (Mus musculus)	3 / 3	SER A 207 ALA A 202 VAL A 201	None	0.61A	4x1iA-3wfhA: undetectable	4x1iA-3wfhA: 20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EYP_B_LOCB502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	3wfh	MAB FAB H FRAGMENT (Mus musculus)	3 / 3	SER A 207 ALA A 202 VAL A 201	None	0.57A	5eypA-3wfhA: undetectable	5eypA-3wfhA: 20.36

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3NYA_A_JTZA1203_1","BETA-2 ADRENERGIC RECEPTOR, LYSOZYME","3wfh","MAB FAB H FRAGMENT","Mus musculus",5,"VAL A 167;VAL A 185;SER A 183;ASN A 200;ASN A 159","None","1.43A","3nyaA-3wfhA:undetectable","3nyaA-3wfhA:18.44"],["3WHX_B_XPGB301_1","MAB FAB H FRAGMENT;MAB FAB L FRAGMENT","3wfh","MAB FAB H FRAGMENT","Mus musculus",8,"PHE A  33;HIS A  35;VAL A  37;TRP A  50;HIS A  99;TYR A 101;PRO A 105;TRP A 107","None","0.10A","3whxA-3wfhA:31.4;3whxB-3wfhA:19.1","3whxA-3wfhA:100.00;3whxB-3wfhA:26.89"],["4X1I_B_LOCB502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","3wfh","MAB FAB H FRAGMENT","Mus musculus",3,"SER A 207;ALA A 202;VAL A 201","None","0.61A","4x1iA-3wfhA:undetectable","4x1iA-3wfhA:20.14"],["5EYP_B_LOCB502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","3wfh","MAB FAB H FRAGMENT","Mus musculus",3,"SER A 207;ALA A 202;VAL A 201","None","0.57A","5eypA-3wfhA:undetectable","5eypA-3wfhA:20.36"]]