SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wg1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 10 THR A  48
PHE A  65
ALA A  64
ASN A  51
VAL A  29
 None
None
LAT  A 201 ( 4.2A)
None
None
 1.33A 1claA-3wg1A:
undetectable		 1claA-3wg1A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 8 ILE A 118
PHE A  96
ARG A  66
LEU A  50
 None
None
LAT  A 201 (-3.0A)
None
 0.88A 2eilN-3wg1A:
undetectable
2eilW-3wg1A:
undetectable		 2eilN-3wg1A:
15.15
2eilW-3wg1A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 12 LEU A  50
VAL A  92
ALA A  93
PHE A  96
LEU A  36
 None
 1.09A 2h42C-3wg1A:
undetectable		 2h42C-3wg1A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 8 ILE A 118
PHE A  96
ARG A  66
LEU A  50
 None
None
LAT  A 201 (-3.0A)
None
 0.92A 3ablN-3wg1A:
undetectable
3ablW-3wg1A:
undetectable		 3ablN-3wg1A:
15.15
3ablW-3wg1A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 8 ILE A 118
PHE A  96
ARG A  66
LEU A  50
 None
None
LAT  A 201 (-3.0A)
None
 0.84A 3ag3N-3wg1A:
undetectable
3ag3W-3wg1A:
undetectable		 3ag3N-3wg1A:
15.15
3ag3W-3wg1A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 6 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
 LAT  A 201 (-3.9A)
LAT  A 201 (-3.0A)
LAT  A 201 (-4.1A)
LAT  A 201 (-3.8A)
LAT  A 201 (-2.8A)
 0.37A 3galA-3wg1A:
16.1		 3galA-3wg1A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 6 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
 LAT  A 201 (-3.9A)
LAT  A 201 (-3.0A)
LAT  A 201 (-4.1A)
LAT  A 201 (-3.8A)
LAT  A 201 (-2.8A)
 0.48A 3galB-3wg1A:
15.6		 3galB-3wg1A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 11 ALA A  49
THR A  48
ALA A  64
ALA A  15
GLY A  14
 None
None
LAT  A 201 ( 4.2A)
None
None
 0.86A 3mg0K-3wg1A:
undetectable
3mg0L-3wg1A:
undetectable		 3mg0K-3wg1A:
19.74
3mg0L-3wg1A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 12 ALA A  49
THR A  48
ALA A  64
ALA A  15
GLY A  14
 None
None
LAT  A 201 ( 4.2A)
None
None
 0.88A 3mg0Y-3wg1A:
undetectable
3mg0Z-3wg1A:
undetectable		 3mg0Y-3wg1A:
19.74
3mg0Z-3wg1A:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 6 VAL A 123
PHE A  74
VAL A 107
PHE A  65
 None
 0.96A 3soaA-3wg1A:
undetectable		 3soaA-3wg1A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 6 LEU A  53
PRO A  79
GLN A  78
TYR A  59
 None
 1.37A 3vkxA-3wg1A:
undetectable		 3vkxA-3wg1A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		5 / 12 SER A  34
ILE A 147
ASN A  37
SER A  39
PHE A  96
 None
 1.20A 4c49A-3wg1A:
undetectable		 4c49A-3wg1A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 7 VAL A 152
ILE A  11
LEU A  61
LEU A  52
 None
 1.04A 4l1wA-3wg1A:
undetectable		 4l1wA-3wg1A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 6 ASP A  18
ASN A  56
ALA A  58
TYR A  59
 None
 1.12A 4mdbA-3wg1A:
undetectable		 4mdbA-3wg1A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 7 ILE A  63
PHE A  74
VAL A 105
ILE A 118
 None
 0.85A 4zzbC-3wg1A:
undetectable
4zzbD-3wg1A:
undetectable		 4zzbC-3wg1A:
21.60
4zzbD-3wg1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 7 ILE A 118
PHE A  96
ARG A  66
LEU A  50
 None
None
LAT  A 201 (-3.0A)
None
 0.92A 5iy5N-3wg1A:
undetectable
5iy5W-3wg1A:
undetectable		 5iy5N-3wg1A:
15.15
5iy5W-3wg1A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		3 / 3 GLY A  26
ASP A  27
ASN A   7
 None
 0.62A 5jglA-3wg1A:
undetectable		 5jglA-3wg1A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGQ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 4 VAL A 107
VAL A 116
TYR A 114
GLN A 125
 None
 1.44A 5qgqA-3wg1A:
undetectable		 5qgqA-3wg1A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 4 VAL A 107
VAL A 116
TYR A 114
GLN A 125
 None
 1.48A 5qhbA-3wg1A:
undetectable		 5qhbA-3wg1A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		6 / 7 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
ARG A  88
 LAT  A 201 (-3.9A)
LAT  A 201 (-3.0A)
LAT  A 201 (-4.1A)
LAT  A 201 (-3.8A)
LAT  A 201 (-2.8A)
LAT  A 201 (-4.4A)
 0.47A 6b8kA-3wg1A:
15.8		 6b8kA-3wg1A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		6 / 8 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
ARG A  88
 LAT  A 201 (-3.9A)
LAT  A 201 (-3.0A)
LAT  A 201 (-4.1A)
LAT  A 201 (-3.8A)
LAT  A 201 (-2.8A)
LAT  A 201 (-4.4A)
 0.55A 6b94A-3wg1A:
14.7		 6b94A-3wg1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		6 / 10 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
ARG A  88
 LAT  A 201 (-3.9A)
LAT  A 201 (-3.0A)
LAT  A 201 (-4.1A)
LAT  A 201 (-3.8A)
LAT  A 201 (-2.8A)
LAT  A 201 (-4.4A)
 0.62A 6b94A-3wg1A:
14.8
6b94B-3wg1A:
14.2		 6b94A-3wg1A:
20.12
6b94B-3wg1A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 4 ARG A  66
GLU A  69
GLU A  86
ARG A  88
 LAT  A 201 (-3.0A)
None
LAT  A 201 (-2.8A)
LAT  A 201 (-4.4A)
 0.85A 6fk2A-3wg1A:
15.8		 6fk2A-3wg1A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3wg1 GALACTOSIDE-BINDING
LECTIN
(Agrocybe
aegerita) 		4 / 4 ARG A  88
GLU A  86
GLU A  69
ARG A  66
 LAT  A 201 (-4.4A)
LAT  A 201 (-2.8A)
None
LAT  A 201 (-3.0A)
 0.97A 6fk2A-3wg1A:
15.8		 6fk2A-3wg1A:
24.71