SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3wge THIOREDOXIN
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		4 / 6 ALA A 231
SER A 195
TRP A 267
LEU A 234
 None
 1.18A 1gahA-3wgeA:
undetectable		 1gahA-3wgeA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 3wge THIOREDOXIN
DOMAIN-CONTAINING
PROTEIN 5
(Homo
sapiens) 		5 / 12 LEU A 286
TRP A 227
VAL A 245
PHE A 268
ASN A 257
 None
 1.38A 2y00B-3wgeA:
undetectable		 2y00B-3wgeA:
14.92