SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 127
LEU A 130
ASN A 131
LEU A 133
LEU A 313
 None
 1.02A 1a28B-3wgoA:
undetectable		 1a28B-3wgoA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQU_A_EQIA329_0
(PROTEIN (ESTRADIOL
17
BETA-DEHYDROGENASE
1))		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 10 VAL A 305
LEU A 118
GLY A 126
PRO A 125
HIS A 102
 None
 1.42A 1equA-3wgoA:
6.5		 1equA-3wgoA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 VAL A 305
LEU A 118
GLY A 126
PRO A 125
HIS A 102
 None
 1.47A 1fdsA-3wgoA:
8.5		 1fdsA-3wgoA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 127
LEU A 130
ASN A 131
LEU A 133
LEU A 313
 None
 0.99A 1sqnA-3wgoA:
undetectable		 1sqnA-3wgoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 127
LEU A 130
ASN A 131
LEU A 133
LEU A 313
 None
 0.94A 1sqnB-3wgoA:
undetectable		 1sqnB-3wgoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 127
LEU A 130
ASN A 131
LEU A 133
LEU A 313
 None
 0.91A 1zucB-3wgoA:
undetectable		 1zucB-3wgoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 130
ASN A 131
LEU A 133
LEU A 313
PHE A 269
 None
 1.15A 1zucB-3wgoA:
undetectable		 1zucB-3wgoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 VAL A 305
LEU A 130
THR A 146
VAL A 253
GLY A 122
 None
 1.08A 2cbrA-3wgoA:
undetectable		 2cbrA-3wgoA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDB_A_NPSA1591_1
(SERUM ALBUMIN)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		4 / 8 ILE A  83
PHE A  35
LEU A  56
GLY A   8
 None
 0.97A 2vdbA-3wgoA:
undetectable		 2vdbA-3wgoA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 127
LEU A 130
ASN A 131
LEU A 133
LEU A 313
 None
 0.97A 2w8yB-3wgoA:
undetectable		 2w8yB-3wgoA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		4 / 5 VAL A  90
GLN A  79
PHE A 103
ARG A  37
 None
 1.15A 3bjwB-3wgoA:
undetectable		 3bjwB-3wgoA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		5 / 12 LEU A 127
LEU A 130
ASN A 131
LEU A 133
LEU A 313
 None
 1.02A 3d90A-3wgoA:
undetectable		 3d90A-3wgoA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		4 / 4 GLY A  13
GLY A  11
THR A  36
LEU A  50
 None
 0.76A 3si7C-3wgoA:
undetectable
3si7D-3wgoA:
undetectable		 3si7C-3wgoA:
22.16
3si7D-3wgoA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		4 / 5 LEU A  50
GLY A  13
GLY A  11
THR A  36
 None
 0.77A 3si7C-3wgoA:
undetectable
3si7D-3wgoA:
undetectable		 3si7C-3wgoA:
22.16
3si7D-3wgoA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		3 / 3 HIS A 244
ASN A 243
LEU A 242
 None
 0.88A 6f7lB-3wgoA:
3.6		 6f7lB-3wgoA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3wgo MESO-DIAMINOPIMELATE
DEHYDROGENASE
(Clostridium
tetani) 		4 / 6 LEU A  76
ALA A  73
SER A 120
THR A 280
 None
 0.94A 6f88A-3wgoA:
undetectable		 6f88A-3wgoA:
14.55