SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wh3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3wh3 C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER E
(Homo
sapiens) 		3 / 3 ASN A 193
PHE A 138
VAL A 195
 CA  A 500 (-3.0A)
None
None
 0.75A 1kijA-3wh3A:
undetectable		 1kijA-3wh3A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3wh3 C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER E
(Homo
sapiens) 		5 / 12 ASN A 119
GLN A 121
ARG A 189
LEU A 158
THR A 156
 CA  A 501 (-3.4A)
None
None
None
None
 1.08A 2q7kA-3wh3A:
undetectable		 2q7kA-3wh3A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB323_0
(INVASIN IPAD)		 3wh3 C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER E
(Homo
sapiens) 		4 / 7 ILE A 204
ILE A 139
LEU A 127
SER A 128
 None
 0.68A 3r9vA-3wh3A:
undetectable
3r9vB-3wh3A:
undetectable		 3r9vA-3wh3A:
19.00
3r9vB-3wh3A:
19.00