SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wh9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_2
(FK506-BINDING
PROTEIN
FRAP)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 LEU A 242
PHE A 206
GLY A 207
TRP A 247
 None
 1.06A 1fapB-3wh9A:
undetectable		 1fapB-3wh9A:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 6 PRO A 169
TRP A  54
GLU A 204
TRP A 112
 None
 1.25A 1ffyA-3wh9A:
0.5		 1ffyA-3wh9A:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 GLU A 276
ASN A  23
TRP A  54
 TRS  A 404 (-2.8A)
None
None
 1.18A 1r15C-3wh9A:
2.1		 1r15C-3wh9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 GLU A 276
ASN A  23
TRP A  54
 TRS  A 404 (-2.8A)
None
None
 1.23A 1r15D-3wh9A:
2.0		 1r15D-3wh9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 GLU A 276
ASN A  23
TRP A  54
 TRS  A 404 (-2.8A)
None
None
 1.19A 1r15E-3wh9A:
2.0		 1r15E-3wh9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 GLU A 276
ASN A  23
TRP A  54
 TRS  A 404 (-2.8A)
None
None
 1.19A 1r15F-3wh9A:
2.0		 1r15F-3wh9A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 TYR A 143
PHE A 133
HIS A  73
MET A 118
 None
 1.08A 1x8vA-3wh9A:
undetectable		 1x8vA-3wh9A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOW_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 7 GLN A 307
TYR A 243
TRP A  54
GLU A 168
 None
TRS  A 404 ( 4.5A)
None
TRS  A 404 (-2.9A)
 1.34A 2aowA-3wh9A:
1.9		 2aowA-3wh9A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		6 / 12 ASN A 167
GLU A 168
HIS A 241
TYR A 243
GLU A 276
TRP A 306
 TRS  A 404 (-2.7A)
TRS  A 404 (-2.9A)
None
TRS  A 404 ( 4.5A)
TRS  A 404 (-2.8A)
TRS  A 404 (-3.7A)
 0.80A 2v3dA-3wh9A:
7.8		 2v3dA-3wh9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 11 ASN A 167
GLU A 168
TYR A 243
GLU A 276
TRP A 306
 TRS  A 404 (-2.7A)
TRS  A 404 (-2.9A)
TRS  A 404 ( 4.5A)
TRS  A 404 (-2.8A)
TRS  A 404 (-3.7A)
 0.86A 2v3dB-3wh9A:
2.1		 2v3dB-3wh9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 12 LEU A 242
GLY A 256
GLY A 254
ALA A 260
THR A 259
 None
 1.11A 3dh0B-3wh9A:
undetectable		 3dh0B-3wh9A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 12 THR A 336
GLN A 291
GLY A 288
ALA A 345
GLY A 343
 None
 1.16A 3v3oA-3wh9A:
undetectable		 3v3oA-3wh9A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 TYR A 146
TYR A  70
VAL A  93
ILE A 106
 None
 1.12A 4aftD-3wh9A:
undetectable
4aftE-3wh9A:
undetectable		 4aftD-3wh9A:
22.02
4aftE-3wh9A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 11 ASP A  58
ALA A 120
GLY A 116
VAL A 109
HIS A  73
 None
 1.36A 4c5lA-3wh9A:
3.2		 4c5lA-3wh9A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 9 ASP A  58
ALA A 120
GLY A 116
VAL A 109
HIS A  73
 None
 1.38A 4c5lB-3wh9A:
3.2		 4c5lB-3wh9A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 10 ASP A  58
ALA A 120
GLY A 116
VAL A 109
HIS A  73
 None
 1.35A 4c5lC-3wh9A:
2.1		 4c5lC-3wh9A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 10 ASP A  58
ALA A 120
GLY A 116
VAL A 109
HIS A  73
 None
 1.36A 4c5nD-3wh9A:
3.1		 4c5nD-3wh9A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 7 GLY A 299
THR A 297
ILE A 258
LEU A 240
 None
 0.81A 4ejjD-3wh9A:
undetectable		 4ejjD-3wh9A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 THR A  22
LEU A  51
VAL A  53
GLN A 307
 None
 0.92A 4em2A-3wh9A:
undetectable		 4em2A-3wh9A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 ILE A  80
ILE A 147
MET A 118
GLY A 117
 None
 0.97A 4hdlA-3wh9A:
undetectable		 4hdlA-3wh9A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 TYR A 115
GLN A 307
TRP A 112
 None
 0.92A 4kn2C-3wh9A:
undetectable		 4kn2C-3wh9A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 6 GLU A 164
TYR A 111
GLU A 168
GLU A 204
 None
None
TRS  A 404 (-2.9A)
None
 1.16A 4mi4A-3wh9A:
undetectable		 4mi4A-3wh9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 7 GLU A 164
TYR A 111
GLU A 168
GLU A 204
 None
None
TRS  A 404 (-2.9A)
None
 1.18A 4mi4B-3wh9A:
undetectable
4mi4C-3wh9A:
undetectable		 4mi4B-3wh9A:
19.02
4mi4C-3wh9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 7 GLU A 164
TYR A 111
GLU A 168
GLU A 204
 None
None
TRS  A 404 (-2.9A)
None
 1.16A 4mi4A-3wh9A:
undetectable
4mi4C-3wh9A:
undetectable		 4mi4A-3wh9A:
19.02
4mi4C-3wh9A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 GLU A 164
TYR A 111
GLU A 168
GLU A 204
 None
None
TRS  A 404 (-2.9A)
None
 1.19A 4mj8A-3wh9A:
1.1
4mj8C-3wh9A:
undetectable		 4mj8A-3wh9A:
18.86
4mj8C-3wh9A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 7 GLU A 164
TYR A 111
GLU A 168
GLU A 204
 None
None
TRS  A 404 (-2.9A)
None
 1.27A 4mj8C-3wh9A:
undetectable		 4mj8C-3wh9A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 9 ASP A  91
VAL A 150
TYR A 154
GLY A  86
GLY A  55
 None
 1.34A 4mmeA-3wh9A:
undetectable		 4mmeA-3wh9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 9 ASP A  91
VAL A 150
TYR A 154
GLY A  86
GLY A  55
 None
 1.36A 4mmfA-3wh9A:
undetectable		 4mmfA-3wh9A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 12 LEU A 273
ALA A 302
LEU A 304
PHE A 161
GLY A  14
 None
 0.91A 4n09C-3wh9A:
undetectable		 4n09C-3wh9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 LEU A 224
MET A 228
TYR A 218
 None
NAG  A 402 (-4.3A)
None
 0.74A 4p6xG-3wh9A:
undetectable		 4p6xG-3wh9A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		3 / 3 ASP A 303
LEU A 304
PHE A 305
 None
 0.61A 4pthA-3wh9A:
undetectable		 4pthA-3wh9A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_B_SAMB303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 5 SER A 313
SER A  96
GLN A  99
ASP A  32
 None
 1.49A 5fhrB-3wh9A:
undetectable		 5fhrB-3wh9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 ARG A 170
GLU A 204
PRO A 217
GLY A 207
 None
 1.12A 5kgpA-3wh9A:
undetectable		 5kgpA-3wh9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 8 ARG A 170
GLU A 204
PRO A 217
GLY A 207
 None
 1.09A 5kgpB-3wh9A:
0.7		 5kgpB-3wh9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		4 / 5 ILE A 183
LEU A 208
GLY A 207
PHE A 226
 None
 0.95A 5kmdC-3wh9A:
undetectable
5kmdD-3wh9A:
undetectable		 5kmdC-3wh9A:
18.56
5kmdD-3wh9A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_A_LLLA302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 3wh9 ENDO-BETA-1,4-MANNAN
ASE
(Aspergillus
niger) 		5 / 10 ASP A 251
GLY A 288
ASP A 319
THR A 323
SER A 281
 None
 1.45A 6mn1A-3wh9A:
0.0		 6mn1A-3wh9A:
13.29