SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3whd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 3whd C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER D
(Homo
sapiens) 		3 / 3 ASN A 195
PHE A 142
VAL A 197
 CA  A 501 (-3.1A)
None
None
 0.59A 1kijA-3whdA:
undetectable		 1kijA-3whdA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3whd C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER D
(Homo
sapiens) 		4 / 6 TRP A 194
LEU A 145
TRP A 154
PHE A 162
 None
 1.45A 1ru9H-3whdA:
undetectable
1ru9L-3whdA:
undetectable		 1ru9H-3whdA:
19.64
1ru9L-3whdA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3whd C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER D
(Homo
sapiens) 		5 / 12 SER A 204
THR A 100
ILE A 131
ASP A 136
LEU A 135
 None
 1.20A 3iv6B-3whdA:
undetectable		 3iv6B-3whdA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 3whd C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER D
(Homo
sapiens) 		4 / 4 ASN A 129
LEU A 143
PHE A 134
TYR A  96
 None
 1.42A 4u14A-3whdA:
undetectable		 4u14A-3whdA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 3whd C-TYPE LECTIN DOMAIN
FAMILY 4 MEMBER D
(Homo
sapiens) 		4 / 6 ILE A 131
TYR A  96
PHE A  91
THR A 160
 None
 1.18A 5g08A-3whdA:
undetectable		 5g08A-3whdA:
24.34