SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3whe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 11 GLU A  89
ARG A 269
GLU A 396
ALA A 113
PHE A  87
GLY A 116
 None
 1.36A 1cmaA-3wheA:
undetectable
1cmaB-3wheA:
undetectable		 1cmaA-3wheA:
11.59
1cmaB-3wheA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 10 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.28A 1cmcA-3wheA:
undetectable
1cmcB-3wheA:
undetectable		 1cmcA-3wheA:
11.59
1cmcB-3wheA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 10 GLU A  89
ARG A 269
GLU A 396
ALA A 113
PHE A  87
GLY A 116
 None
 1.30A 1cmcA-3wheA:
undetectable
1cmcB-3wheA:
undetectable		 1cmcA-3wheA:
11.59
1cmcB-3wheA:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3whe HEMAGGLUTININ
IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens;
Influenza
A
virus) 		4 / 6 TRP M  50
GLY M 104
ASN M  52
PRO A 284
 None
NAG  A 601 (-3.6A)
None
None
 1.38A 1dedA-3wheM:
3.5		 1dedA-3wheM:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 12 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.36A 1mj2A-3wheA:
undetectable
1mj2B-3wheA:
undetectable		 1mj2A-3wheA:
12.03
1mj2B-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 12 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.36A 1mj2C-3wheA:
undetectable
1mj2D-3wheA:
undetectable		 1mj2C-3wheA:
12.03
1mj2D-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 9 GLU A  89
ARG A 269
GLU A 396
PHE A  87
GLY A 116
 None
 1.17A 1mjlA-3wheA:
undetectable
1mjlB-3wheA:
undetectable		 1mjlA-3wheA:
12.03
1mjlB-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 12 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.33A 1mjoC-3wheA:
undetectable
1mjoD-3wheA:
undetectable		 1mjoC-3wheA:
12.03
1mjoD-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 11 GLU A  89
ARG A 269
GLU A 396
ALA A 113
PHE A  87
GLY A 116
 None
 1.30A 1mjqA-3wheA:
undetectable
1mjqB-3wheA:
undetectable		 1mjqA-3wheA:
12.03
1mjqB-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.17A 1mjqA-3wheA:
undetectable
1mjqB-3wheA:
undetectable		 1mjqA-3wheA:
12.03
1mjqB-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 10 GLU A  89
ARG A 269
GLU A 396
ALA A 113
PHE A  87
GLY A 116
 None
 1.32A 1mjqC-3wheA:
undetectable
1mjqD-3wheA:
undetectable		 1mjqC-3wheA:
12.03
1mjqD-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 12 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.34A 1mjqC-3wheA:
undetectable
1mjqD-3wheA:
undetectable		 1mjqC-3wheA:
12.03
1mjqD-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 10 GLU A  89
ARG A 269
GLU A 396
ALA A 113
PHE A  87
GLY A 116
 None
 1.30A 1mjqG-3wheA:
undetectable
1mjqH-3wheA:
undetectable		 1mjqG-3wheA:
12.03
1mjqH-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.16A 1mjqG-3wheA:
undetectable
1mjqH-3wheA:
undetectable		 1mjqG-3wheA:
12.03
1mjqH-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 11 GLU A  89
ARG A 269
GLU A 396
ALA A 113
PHE A  87
GLY A 116
 None
 1.32A 1mjqI-3wheA:
undetectable
1mjqJ-3wheA:
undetectable		 1mjqI-3wheA:
12.03
1mjqJ-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		6 / 12 ALA A 113
PHE A  87
GLY A 116
GLU A  89
ARG A 269
GLU A 396
 None
 1.34A 1mjqI-3wheA:
undetectable
1mjqJ-3wheA:
undetectable		 1mjqI-3wheA:
12.03
1mjqJ-3wheA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 ASP A 461
GLY A 463
GLY A 465
ASN A 464
THR A 451
 None
 1.11A 2c49A-3wheA:
undetectable		 2c49A-3wheA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 5 SER M 190
VAL M 182
SER M 192
VAL M 155
 None
 1.26A 2j9cA-3wheM:
undetectable
2j9cB-3wheM:
undetectable
2j9cC-3wheM:
undetectable		 2j9cA-3wheM:
18.34
2j9cB-3wheM:
18.34
2j9cC-3wheM:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 ASP A 172
ASN A 170
THR A 167
 None
None
NAG  A 609 (-3.4A)
 0.74A 2pymB-3wheA:
undetectable		 2pymB-3wheA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 ASP A 172
ASN A 170
THR A 167
 None
None
NAG  A 609 (-3.4A)
 0.75A 2q63B-3wheA:
undetectable		 2q63B-3wheA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 ASN A  81
ARG A 141
ASP A  77
ALA A  69
HIS A  75
 NAG  A 608 (-1.8A)
None
None
None
None
 1.50A 2qmjA-3wheA:
undetectable		 2qmjA-3wheA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 TYR A 100
VAL A 102
TYR A 105
ASP A  68
 None
 1.47A 2x45A-3wheA:
undetectable		 2x45A-3wheA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 GLY A 342
VAL A 323
GLY A  23
THR A  24
 None
 0.92A 3ib2A-3wheA:
undetectable		 3ib2A-3wheA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TRP M  47
ALA M  97
VAL M  37
 None
 0.98A 3l8lC-3wheM:
undetectable
3l8lD-3wheM:
undetectable		 3l8lC-3wheM:
5.20
3l8lD-3wheM:
5.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 GLY A 342
PRO A 324
GLY A  23
THR A  24
 None
 0.70A 3tajA-3wheA:
undetectable		 3tajA-3wheA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 PHE A 392
TYR A 302
HIS A  56
ILE A  58
 None
 0.87A 4g5jA-3wheA:
undetectable		 4g5jA-3wheA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 ASN A 248
SER A 247
LEU A 251
VAL A 182
ILE A 252
 None
 1.39A 4k37B-3wheA:
undetectable		 4k37B-3wheA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 ASN A 464
MET A 462
PHE A 338
TRP A 343
 None
 1.49A 4v2zB-3wheA:
undetectable		 4v2zB-3wheA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 ARG A 269
HIS A 393
ALA A 113
GLU A 396
 None
 1.44A 5a06A-3wheA:
0.0
5a06F-3wheA:
0.0		 5a06A-3wheA:
20.00
5a06F-3wheA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 8 SER M  35
TRP M  47
TRP M  50
TYR M 111
 None
 1.26A 5amiB-3wheM:
undetectable		 5amiB-3wheM:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TYR M  80
THR M  19
THR M  71
 None
 0.78A 5aoxB-3wheM:
undetectable		 5aoxB-3wheM:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		3 / 3 TYR M  80
THR M  19
THR M  71
 None
 0.75A 5aoxE-3wheM:
undetectable		 5aoxE-3wheM:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 PRO A 215
LEU A 194
SER A 199
 None
 0.74A 5fsaB-3wheA:
undetectable		 5fsaB-3wheA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		4 / 8 ASP A  73
ASP A  68
HIS A  75
ARG A 229
 None
 0.98A 5nekB-3wheA:
undetectable		 5nekB-3wheA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 VAL M  48
VAL M  37
TYR M  94
GLN M  39
 None
 1.49A 5qggA-3wheM:
undetectable		 5qggA-3wheM:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGO_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 VAL M  48
VAL M  37
TYR M  94
GLN M  39
 None
 1.45A 5qgoA-3wheM:
undetectable		 5qgoA-3wheM:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGP_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 VAL M  48
VAL M  37
TYR M  94
GLN M  39
 None
 1.44A 5qgpA-3wheM:
undetectable		 5qgpA-3wheM:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHB_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		4 / 4 VAL M  48
VAL M  37
TYR M  94
GLN M  39
 None
 1.46A 5qhbA-3wheM:
undetectable		 5qhbA-3wheM:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU A  82
LEU A 118
ARG A 150
 None
None
NAG  A 608 ( 4.0A)
 0.77A 6d8fA-3wheA:
undetectable		 6d8fA-3wheA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3whe IMMUNOGLOBULIN HEAVY
CHAIN
(Homo
sapiens) 		5 / 12 VAL M 220
THR M 218
VAL M 224
GLY M 131
VAL M 165
 None
 1.08A 6drzA-3wheM:
undetectable		 6drzA-3wheM:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 ARG A 261
PHE A 120
PHE A 174
 None
 0.84A 6nknC-3wheA:
undetectable
6nknJ-3wheA:
undetectable		 6nknC-3wheA:
18.60
6nknJ-3wheA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 SER A 228
ALA A 138
TRP A 153
SER A 136
HIS A 183
 None
 1.44A 6qgbA-3wheA:
undetectable		 6qgbA-3wheA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_B_BEZB802_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 SER A 228
ALA A 138
TRP A 153
SER A 136
HIS A 183
 None
 1.46A 6qgbB-3wheA:
undetectable		 6qgbB-3wheA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_D_BEZD701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 SER A 228
ALA A 138
TRP A 153
SER A 136
HIS A 183
 None
 1.48A 6qgbD-3wheA:
undetectable		 6qgbD-3wheA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 SER A 228
ALA A 138
TRP A 153
SER A 136
HIS A 183
 None
 1.42A 6qgbE-3wheA:
undetectable		 6qgbE-3wheA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_F_BEZF701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 3whe HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 SER A 228
ALA A 138
TRP A 153
SER A 136
HIS A 183
 None
 1.48A 6qgbF-3wheA:
undetectable		 6qgbF-3wheA:
21.89