SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3whj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A164_1
(BETA-LACTOGLOBULIN)		 3whj PROBABLE 26S
PROTEASOME
REGULATORY SUBUNIT
P27
(Saccharomyces
cerevisiae) 		4 / 5 ASP A  40
LEU A  37
LYS A  38
ARG A  22
 None
None
CD  A 205 ( 2.3A)
None
 1.43A 2gj5A-3whjA:
undetectable		 2gj5A-3whjA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_C_GLYC73_0
(NONSTRUCTURAL
PROTEIN 1)		 3whj PROBABLE 26S
PROTEASOME
REGULATORY SUBUNIT
P27
(Saccharomyces
cerevisiae) 		4 / 4 ASP A  40
ASP A  16
SER A  18
ARG A  22
 None
 1.00A 2z0aC-3whjA:
3.7		 2z0aC-3whjA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3whj PROBABLE 26S
PROTEASOME
REGULATORY SUBUNIT
P27
(Saccharomyces
cerevisiae) 		4 / 6 SER A  61
VAL A  79
THR A  80
ARG A  83
 None
 1.29A 4lnxA-3whjA:
undetectable		 4lnxA-3whjA:
25.11