SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wiq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 HIS A 313
HIS A 333
LEU A  27
THR A  28
 None
 1.05A 1am6A-3wiqA:
undetectable		 1am6A-3wiqA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 5 TYR A 638
GLU A 647
TYR A 620
ASP A 621
 None
 1.33A 1i7zB-3wiqA:
2.9		 1i7zB-3wiqA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 GLY A 449
LEU A 508
SER A 506
LEU A 512
LEU A 529
 None
 1.03A 1ya4A-3wiqA:
undetectable		 1ya4A-3wiqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 VAL A  54
ASP A 395
THR A 190
LEU A  68
 None
 1.03A 1z2bB-3wiqA:
undetectable		 1z2bB-3wiqA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 ALA A 360
ALA A 361
ASN A 434
LEU A 350
ILE A 718
 None
 0.95A 2aclA-3wiqA:
undetectable
2aclE-3wiqA:
undetectable		 2aclA-3wiqA:
16.01
2aclE-3wiqA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 ALA A 360
ALA A 361
LEU A 350
ALA A 318
ILE A 718
 None
 0.99A 2aclA-3wiqA:
undetectable
2aclE-3wiqA:
undetectable		 2aclA-3wiqA:
16.01
2aclE-3wiqA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 ALA A 360
ALA A 361
ASN A 434
LEU A 350
ILE A 718
 None
 0.98A 2aclE-3wiqA:
undetectable		 2aclE-3wiqA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 ALA A 360
ALA A 361
LEU A 350
ALA A 318
ILE A 718
 None
 0.91A 2aclE-3wiqA:
undetectable		 2aclE-3wiqA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 ALA A 360
ALA A 361
ASN A 434
LEU A 350
ALA A 318
 None
 0.79A 2aclG-3wiqA:
undetectable		 2aclG-3wiqA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 TYR A 286
TYR A 353
HIS A 333
GLY A 331
 None
 1.20A 2ha4B-3wiqA:
undetectable		 2ha4B-3wiqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 LEU A 606
TYR A 493
ILE A 637
ILE A 347
 None
 0.91A 2q8hA-3wiqA:
undetectable		 2q8hA-3wiqA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 9 LEU A 503
ILE A 544
ALA A 498
GLY A 608
LEU A 607
 None
 1.26A 2v0mB-3wiqA:
undetectable		 2v0mB-3wiqA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 PHE A 309
ILE A  37
THR A 670
ILE A  72
 None
 0.64A 2v0mB-3wiqA:
undetectable		 2v0mB-3wiqA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 MET A 128
SER A 316
GLY A 102
TRP A 290
 None
 1.24A 2y7pA-3wiqA:
undetectable		 2y7pA-3wiqA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 ILE A  34
LEU A  27
THR A 246
GLY A  33
 None
 0.83A 3dcjB-3wiqA:
undetectable		 3dcjB-3wiqA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		3 / 3 ARG A 739
ILE A 718
TRP A 719
 None
 1.17A 3e68A-3wiqA:
undetectable		 3e68A-3wiqA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 LEU A 327
GLY A 680
LEU A 663
SER A 316
ILE A  10
 None
 0.98A 3frqB-3wiqA:
undetectable		 3frqB-3wiqA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 VAL A 126
LEU A 314
ILE A  72
ILE A  32
 None
 0.95A 3gcsA-3wiqA:
undetectable		 3gcsA-3wiqA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 LEU A 365
ILE A 452
PHE A 459
GLU A 346
ASP A 427
 None
 1.43A 3ko0A-3wiqA:
undetectable
3ko0B-3wiqA:
undetectable
3ko0C-3wiqA:
undetectable
3ko0D-3wiqA:
undetectable		 3ko0A-3wiqA:
9.49
3ko0B-3wiqA:
9.49
3ko0C-3wiqA:
9.49
3ko0D-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 SER A 393
LEU A 365
PHE A 459
GLU A 346
ASP A 427
 None
 1.37A 3ko0A-3wiqA:
undetectable
3ko0B-3wiqA:
undetectable
3ko0C-3wiqA:
undetectable
3ko0D-3wiqA:
undetectable		 3ko0A-3wiqA:
9.49
3ko0B-3wiqA:
9.49
3ko0C-3wiqA:
9.49
3ko0D-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 GLU A 346
ASP A 427
LEU A 365
ILE A 452
PHE A 459
 None
 1.46A 3ko0E-3wiqA:
undetectable
3ko0F-3wiqA:
undetectable
3ko0G-3wiqA:
undetectable
3ko0H-3wiqA:
undetectable		 3ko0E-3wiqA:
9.49
3ko0F-3wiqA:
9.49
3ko0G-3wiqA:
9.49
3ko0H-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 GLU A 346
ASP A 427
LEU A 365
PHE A 459
SER A 393
 None
 1.39A 3ko0E-3wiqA:
undetectable
3ko0F-3wiqA:
undetectable
3ko0G-3wiqA:
undetectable
3ko0H-3wiqA:
undetectable		 3ko0E-3wiqA:
9.49
3ko0F-3wiqA:
9.49
3ko0G-3wiqA:
9.49
3ko0H-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 LEU A 365
ILE A 452
PHE A 459
GLU A 346
ASP A 427
 None
 1.48A 3ko0O-3wiqA:
undetectable
3ko0P-3wiqA:
undetectable
3ko0Q-3wiqA:
undetectable
3ko0R-3wiqA:
undetectable		 3ko0O-3wiqA:
9.49
3ko0P-3wiqA:
9.49
3ko0Q-3wiqA:
9.49
3ko0R-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 LEU A 365
PHE A 459
GLU A 346
ASP A 427
SER A 393
 None
 1.40A 3ko0O-3wiqA:
undetectable
3ko0P-3wiqA:
undetectable
3ko0Q-3wiqA:
undetectable
3ko0R-3wiqA:
undetectable		 3ko0O-3wiqA:
9.49
3ko0P-3wiqA:
9.49
3ko0Q-3wiqA:
9.49
3ko0R-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 10 LEU A 365
ILE A 452
PHE A 459
GLU A 346
ASP A 427
 None
 1.42A 3ko0O-3wiqA:
undetectable
3ko0P-3wiqA:
undetectable
3ko0Q-3wiqA:
undetectable
3ko0R-3wiqA:
0.0		 3ko0O-3wiqA:
9.49
3ko0P-3wiqA:
9.49
3ko0Q-3wiqA:
9.49
3ko0R-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 10 SER A 393
LEU A 365
PHE A 459
GLU A 346
ASP A 427
 None
 1.43A 3ko0O-3wiqA:
undetectable
3ko0P-3wiqA:
undetectable
3ko0Q-3wiqA:
undetectable
3ko0R-3wiqA:
0.0		 3ko0O-3wiqA:
9.49
3ko0P-3wiqA:
9.49
3ko0Q-3wiqA:
9.49
3ko0R-3wiqA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 TYR A 493
ASP A 344
ALA A 677
SER A 631
 None
GLC  A 801 (-2.4A)
None
SO4  A 803 (-3.5A)
 1.08A 3rodA-3wiqA:
undetectable		 3rodA-3wiqA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROZ_A_NCAA266_0
(APOLIPOPROTEIN
A-I-BINDING PROTEIN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 ASP A 221
LEU A 222
ALA A 157
LEU A 187
 None
 1.06A 3rozA-3wiqA:
undetectable		 3rozA-3wiqA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 HIS A 485
GLU A 421
ASP A 344
ASP A 482
 None
None
GLC  A 801 (-2.4A)
None
 1.34A 3vywA-3wiqA:
undetectable		 3vywA-3wiqA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 PHE A 655
VAL A 307
ILE A 311
ASN A 310
 None
 0.94A 4a97E-3wiqA:
3.0		 4a97E-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 PHE A 655
VAL A 307
ILE A 311
ASN A 310
 None
 0.93A 4a97C-3wiqA:
3.0		 4a97C-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 PHE A 655
VAL A 307
ILE A 311
ASN A 310
 None
 0.93A 4a97D-3wiqA:
3.0		 4a97D-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_H_ZPCH1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 PHE A 655
VAL A 307
ILE A 311
ASN A 310
 None
 0.93A 4a97G-3wiqA:
1.6		 4a97G-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 PHE A 655
VAL A 307
ILE A 311
ASN A 310
 None
 0.91A 4a97H-3wiqA:
0.1		 4a97H-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 PHE A 655
VAL A 307
ILE A 311
ASN A 310
 None
 0.92A 4a97I-3wiqA:
3.0		 4a97I-3wiqA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 SER A 634
GLN A 557
PHE A 558
ILE A 479
 None
 0.97A 4dx7B-3wiqA:
undetectable		 4dx7B-3wiqA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 GLY A 122
ASN A  38
GLU A  39
GLN A 101
 None
 1.32A 4g0vB-3wiqA:
2.1		 4g0vB-3wiqA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD305_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 4 ILE A 295
LEU A 714
LYS A 715
ASN A 304
 None
 1.03A 4g19D-3wiqA:
undetectable		 4g19D-3wiqA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 5 LEU A 108
ARG A 106
ILE A 242
ASN A 150
 None
 1.47A 4i00A-3wiqA:
undetectable		 4i00A-3wiqA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KT0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 GLY A 334
ALA A  26
GLY A  48
ILE A 120
LEU A 110
 None
 1.01A 4kt0A-3wiqA:
undetectable
4kt0J-3wiqA:
undetectable		 4kt0A-3wiqA:
20.05
4kt0J-3wiqA:
4.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 GLY A  30
LEU A 248
TYR A  31
ASN A  29
 None
 0.97A 4m5mA-3wiqA:
undetectable		 4m5mA-3wiqA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 9 THR A  49
GLY A  48
LEU A  68
PRO A  71
VAL A  66
 None
 1.50A 4mjrA-3wiqA:
undetectable		 4mjrA-3wiqA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 MET A 641
ILE A 297
ILE A 295
VAL A 307
 None
 0.90A 4olmA-3wiqA:
undetectable		 4olmA-3wiqA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 5 HIS A 172
VAL A  66
GLU A  64
VAL A 170
 None
 1.47A 4p6vB-3wiqA:
undetectable
4p6vE-3wiqA:
undetectable		 4p6vB-3wiqA:
21.69
4p6vE-3wiqA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 PHE A 309
LEU A 679
HIS A 333
THR A  23
 None
 1.26A 4paeA-3wiqA:
undetectable		 4paeA-3wiqA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.25A 4qvnH-3wiqA:
undetectable
4qvnI-3wiqA:
undetectable		 4qvnH-3wiqA:
16.69
4qvnI-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 10 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.25A 4qvnV-3wiqA:
undetectable
4qvnW-3wiqA:
0.7		 4qvnV-3wiqA:
16.69
4qvnW-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.24A 4qvqH-3wiqA:
undetectable
4qvqI-3wiqA:
undetectable		 4qvqH-3wiqA:
16.69
4qvqI-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.24A 4qvqV-3wiqA:
undetectable
4qvqW-3wiqA:
0.7		 4qvqV-3wiqA:
16.69
4qvqW-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.27A 4qw0H-3wiqA:
undetectable
4qw0I-3wiqA:
undetectable		 4qw0H-3wiqA:
16.69
4qw0I-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.27A 4qw0V-3wiqA:
undetectable
4qw0W-3wiqA:
undetectable		 4qw0V-3wiqA:
16.69
4qw0W-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.27A 4qw1H-3wiqA:
undetectable
4qw1I-3wiqA:
undetectable		 4qw1H-3wiqA:
16.69
4qw1I-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.27A 4qw1V-3wiqA:
undetectable
4qw1W-3wiqA:
undetectable		 4qw1V-3wiqA:
16.69
4qw1W-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.25A 4qwuH-3wiqA:
undetectable
4qwuI-3wiqA:
0.0		 4qwuH-3wiqA:
16.69
4qwuI-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 11 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.25A 4qwuV-3wiqA:
undetectable
4qwuW-3wiqA:
0.7		 4qwuV-3wiqA:
16.69
4qwuW-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 TYR A 337
GLU A 421
THR A 417
TRP A 343
 GLC  A 801 ( 4.0A)
None
BGC  A 802 (-3.0A)
GLC  A 801 (-4.4A)
 1.44A 4qztA-3wiqA:
undetectable		 4qztA-3wiqA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 TYR A 337
GLU A 421
THR A 417
TRP A 343
 GLC  A 801 ( 4.0A)
None
BGC  A 802 (-3.0A)
GLC  A 801 (-4.4A)
 1.46A 4qzuC-3wiqA:
undetectable		 4qzuC-3wiqA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		3 / 3 ARG A 739
THR A 356
TRP A 719
 None
 1.25A 4ug5A-3wiqA:
undetectable		 4ug5A-3wiqA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 VAL A 126
ILE A  72
HIS A 313
LEU A  97
 None
 1.17A 4xo7B-3wiqA:
undetectable		 4xo7B-3wiqA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 ASP A 156
THR A 158
LYS A 171
LEU A 187
GLY A 188
 None
 1.32A 5axdA-3wiqA:
undetectable		 5axdA-3wiqA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 ASP A 156
THR A 158
LYS A 171
LEU A 187
GLY A 188
 None
 1.31A 5axdC-3wiqA:
undetectable		 5axdC-3wiqA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 THR A 658
SER A 632
GLN A 597
GLY A 681
ALA A 677
 None
SO4  A 803 (-3.0A)
GLC  A 801 (-3.2A)
None
None
 1.25A 5cz7V-3wiqA:
undetectable
5cz7W-3wiqA:
undetectable		 5cz7V-3wiqA:
16.69
5cz7W-3wiqA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 5 ASN A 310
HIS A 675
THR A 661
CYH A  24
 None
SO4  A 803 (-3.8A)
None
None
 1.46A 5eu8A-3wiqA:
undetectable		 5eu8A-3wiqA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 9 ILE A 555
PRO A 547
VAL A 478
ILE A 475
LEU A 604
 None
 1.48A 5iepA-3wiqA:
undetectable		 5iepA-3wiqA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_2
(TUBULIN ALPHA-1B
CHAIN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 LEU A 187
PRO A  69
VAL A 198
GLY A 199
ILE A 200
 None
 0.58A 5j2tC-3wiqA:
undetectable		 5j2tC-3wiqA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 LEU A  74
VAL A  41
GLU A  45
ILE A 200
 None
 1.17A 5jh7C-3wiqA:
undetectable		 5jh7C-3wiqA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		3 / 3 LYS A 163
ASP A 164
ARG A  35
 None
 0.92A 5jwaA-3wiqA:
undetectable
5jwaH-3wiqA:
undetectable		 5jwaA-3wiqA:
22.27
5jwaH-3wiqA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 HIS A 313
HIS A 333
LEU A  27
THR A  28
 None
 1.10A 5ogjA-3wiqA:
undetectable		 5ogjA-3wiqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 HIS A 313
HIS A 333
LEU A  27
THR A  28
 None
 1.10A 5ogjB-3wiqA:
undetectable		 5ogjB-3wiqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 5 HIS A 313
HIS A 333
LEU A  27
THR A  28
 None
 1.11A 5ohhA-3wiqA:
undetectable		 5ohhA-3wiqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 HIS A 313
HIS A 333
LEU A  27
THR A  28
 None
 1.11A 5ohhB-3wiqA:
undetectable		 5ohhB-3wiqA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 6 PRO A  69
VAL A  66
VAL A  54
ILE A 189
 None
 0.91A 5pbeA-3wiqA:
undetectable		 5pbeA-3wiqA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 GLU A  64
VAL A 165
GLY A 336
LEU A 672
 None
 0.99A 5sxtA-3wiqA:
undetectable		 5sxtA-3wiqA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 7 SER A 450
ILE A 453
LEU A 508
LEU A 512
 None
 0.97A 5u4sA-3wiqA:
undetectable		 5u4sA-3wiqA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 SER A 450
ILE A 453
LEU A 508
LEU A 512
 None
 0.99A 5u4sB-3wiqA:
undetectable		 5u4sB-3wiqA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 12 PHE A 181
GLY A 188
GLY A 199
TYR A 173
ILE A 175
 None
 1.16A 6b3bA-3wiqA:
undetectable		 6b3bA-3wiqA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		4 / 8 TYR A  31
VAL A 198
THR A 191
VAL A  66
 None
 0.83A 6cp4A-3wiqA:
undetectable		 6cp4A-3wiqA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3wiq KOJIBIOSE
PHOSPHORYLASE
(Caldicellulosiru
ptor
saccharolyticus) 		5 / 9 LEU A 714
SER A 713
ILE A 295
VAL A 307
ILE A 297
 None
 1.24A 6ef6A-3wiqA:
1.4		 6ef6A-3wiqA:
19.22