SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4H_A_REAA500_1
(NUCLEAR RECEPTOR
ROR-BETA)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 11 ILE A 196
ALA A 328
VAL A 182
ARG A 319
LEU A 246
 None
 1.13A 1n4hA-3wj7A:
undetectable		 1n4hA-3wj7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 PRO A 320
ASP A 219
ASP A 327
 None
 0.80A 1sqfA-3wj7A:
6.3		 1sqfA-3wj7A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 SER A 179
GLU A 242
ASP A 323
 None
 0.82A 2avdB-3wj7A:
5.9		 2avdB-3wj7A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_D_T44D328_1
(5-HYDROXYISOURATE
HYDROLASE)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 9 LEU A  30
LEU A  37
THR A  16
LEU A  78
LEU A  14
 None
 1.35A 3q1eB-3wj7A:
undetectable
3q1eD-3wj7A:
undetectable		 3q1eB-3wj7A:
17.54
3q1eD-3wj7A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 9 ARG A 322
ALA A 328
ASP A 186
LEU A 197
ILE A 329
 None
 1.46A 3wsjA-3wj7A:
undetectable		 3wsjA-3wj7A:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 9 ASP A 137
PRO A 178
VAL A 124
SER A 306
GLY A 240
 None
 1.33A 4mm5A-3wj7A:
undetectable		 4mm5A-3wj7A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		5 / 10 ALA A  25
VAL A  81
LEU A  53
VAL A  15
HIS A 224
 None
 1.27A 5eb5B-3wj7A:
undetectable		 5eb5B-3wj7A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3wj7 PUTATIVE
OXIDOREDUCTASE
(Gluconobacter
oxydans) 		3 / 3 LYS A 169
LEU A 165
ARG A 164
 None
 0.55A 5yw0A-3wj7A:
undetectable		 5yw0A-3wj7A:
21.15