SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wjt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3wjt OUTER-MEMBRANE
LIPOPROTEIN LOLB
(Escherichia
coli) 		3 / 3 PRO A 164
GLY A 120
TYR A 152
 None
 0.71A 2vouA-3wjtA:
undetectable		 2vouA-3wjtA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3wjt OUTER-MEMBRANE
LIPOPROTEIN LOLB
(Escherichia
coli) 		3 / 3 PRO A 164
GLY A 120
TYR A 152
 None
 0.62A 2vouB-3wjtA:
undetectable		 2vouB-3wjtA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3wjt OUTER-MEMBRANE
LIPOPROTEIN LOLB
(Escherichia
coli) 		3 / 3 PRO A 164
GLY A 120
TYR A 152
 None
 0.61A 2vouC-3wjtA:
undetectable		 2vouC-3wjtA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3wjt OUTER-MEMBRANE
LIPOPROTEIN LOLB
(Escherichia
coli) 		3 / 3 SER A  41
GLU A  72
ASP A  68
 None
 0.72A 2zulA-3wjtA:
undetectable		 2zulA-3wjtA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3wjt OUTER-MEMBRANE
LIPOPROTEIN LOLB
(Escherichia
coli) 		3 / 3 SER A  41
GLU A  72
ASP A  68
 None
 0.75A 3dmhA-3wjtA:
undetectable		 3dmhA-3wjtA:
19.44