SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wkm'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_A_FOLA605_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	0.94A	1qzfA-3wkmA: undetectable	1qzfA-3wkmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_B_FOLB609_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	0.94A	1qzfB-3wkmA: undetectable	1qzfB-3wkmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_C_FOLC613_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	0.94A	1qzfC-3wkmA: undetectable	1qzfC-3wkmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_D_FOLD617_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	0.94A	1qzfD-3wkmA: undetectable	1qzfD-3wkmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QZF_E_FOLE621_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	0.95A	1qzfE-3wkmA: undetectable	1qzfE-3wkmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_A_MTXA605_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	1.01A	2oipA-3wkmA: undetectable	2oipA-3wkmA: 14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_D_MTXD615_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 12	VAL A 154 LEU A 179 THR A 175 ILE A 190 LEU A 201	None	1.12A	3hj3D-3wkmA: undetectable	3hj3D-3wkmA: 14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_A_TMQA202_2 (DIHYDROFOLATE REDUCTASE)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	3 / 3	TRP A 242 GLN A 130 THR A 241	None	0.99A	4m2xA-3wkmA: undetectable	4m2xA-3wkmA: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_B_HISB402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 9	VAL A 234 VAL A 246 LEU A 259 GLY A 286 LEU A 287	None	1.26A	6czmA-3wkmA: undetectable 6czmB-3wkmA: undetectable	6czmA-3wkmA: 23.40 6czmB-3wkmA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_C_HISC402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 9	VAL A 234 VAL A 246 LEU A 259 GLY A 286 LEU A 287	None	1.27A	6czmB-3wkmA: undetectable 6czmC-3wkmA: undetectable	6czmB-3wkmA: 23.40 6czmC-3wkmA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_E_HISE402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 9	VAL A 234 VAL A 246 LEU A 259 GLY A 286 LEU A 287	None	1.28A	6czmD-3wkmA: undetectable 6czmE-3wkmA: undetectable	6czmD-3wkmA: 23.40 6czmE-3wkmA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CZM_F_HISF402_0 (ATP PHOSPHORIBOSYLTRANSF ERASE CATALYTIC SUBUNIT)	3wkm	PUTATIVE ZINC METALLOPROTEASE AQ_1964 (Aquifex aeolicus)	5 / 10	VAL A 234 VAL A 246 LEU A 259 GLY A 286 LEU A 287	None	1.24A	6czmE-3wkmA: undetectable 6czmF-3wkmA: undetectable	6czmE-3wkmA: 23.40 6czmF-3wkmA: 23.40