SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wky'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 THR A 119
ALA A 115
THR A  47
LEU A  96
LEU A  57
 None
 1.16A 1eiiA-3wkyA:
undetectable		 1eiiA-3wkyA:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 GLY A 583
LEU A 240
ASP A 586
GLY A 587
THR A 448
 None
 1.04A 1jg3A-3wkyA:
undetectable		 1jg3A-3wkyA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 GLY A 583
LEU A 240
ASP A 586
GLY A 587
THR A 448
 None
 1.04A 1jg3B-3wkyA:
undetectable		 1jg3B-3wkyA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 GLY A 345
GLU A 340
LEU A 304
GLY A 219
GLU A 343
 None
 1.38A 2fn1A-3wkyA:
undetectable		 2fn1A-3wkyA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_2
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		3 / 3 ASN A 492
ILE A 489
MET A 656
 None
 0.82A 2h42C-3wkyA:
undetectable		 2h42C-3wkyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 ALA A 341
LEU A 342
LEU A 304
GLY A 311
LEU A 323
 None
 1.11A 2jfaB-3wkyA:
undetectable		 2jfaB-3wkyA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		3 / 3 ARG A 504
ASN A 493
THR A 535
 None
 0.86A 2q63A-3wkyA:
undetectable		 2q63A-3wkyA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 6 LEU A 138
PHE A  70
ASP A 362
GLU A 385
 None
 1.31A 2vn1B-3wkyA:
undetectable		 2vn1B-3wkyA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		3 / 3 PHE A 567
ASN A 194
PHE A 479
 None
 0.86A 2zbuD-3wkyA:
undetectable		 2zbuD-3wkyA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.71A 2zweA-3wkyA:
10.3
2zweB-3wkyA:
undetectable		 2zweA-3wkyA:
18.10
2zweB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.74A 2zwfA-3wkyA:
10.3
2zwfB-3wkyA:
undetectable		 2zwfA-3wkyA:
18.10
2zwfB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.73A 2zwgA-3wkyA:
10.5
2zwgB-3wkyA:
undetectable		 2zwgA-3wkyA:
18.10
2zwgB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 6 TYR A 520
ALA A 521
LEU A 524
THR A 410
 None
 0.84A 3b6hA-3wkyA:
undetectable		 3b6hA-3wkyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 6 TYR A 520
ALA A 521
LEU A 524
THR A 410
 None
 0.78A 3b6hB-3wkyA:
undetectable		 3b6hB-3wkyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 4 LEU A 204
ARG A 141
LEU A 134
ALA A 110
 None
 1.11A 3b9mA-3wkyA:
undetectable		 3b9mA-3wkyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAT_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 4 MET A 193
LYS A 476
ASN A 577
THR A 136
 None
 1.37A 3datA-3wkyA:
0.0		 3datA-3wkyA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 PRO A 575
SER A 197
LEU A 555
SER A 556
 None
 1.03A 3iluH-3wkyA:
undetectable		 3iluH-3wkyA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 ARG A 141
ASP A 140
TYR A 117
LEU A 204
GLU A 385
 None
 1.46A 3lmyA-3wkyA:
undetectable		 3lmyA-3wkyA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 LEU A 113
GLY A 460
LEU A 134
PRO A 133
TYR A 117
 None
 1.28A 3mecA-3wkyA:
undetectable		 3mecA-3wkyA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SU9_A_ACTA426_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		3 / 3 GLN A 411
GLU A 637
LYS A 408
 None
 1.16A 3su9A-3wkyA:
undetectable		 3su9A-3wkyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T8N_D_EDTD135_0
(STEROID
DELTA-ISOMERASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 THR A 410
PRO A 412
ARG A 638
THR A 324
GLY A 334
 None
 1.22A 3t8nD-3wkyA:
undetectable
3t8nF-3wkyA:
undetectable		 3t8nD-3wkyA:
12.46
3t8nF-3wkyA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 GLY A 460
SER A 459
SER A 457
PHE A 567
 None
NAG  A 703 (-4.7A)
None
None
 0.86A 3v7pA-3wkyA:
undetectable		 3v7pA-3wkyA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 VAL A 660
LEU A 446
ILE A 662
VAL A 530
 None
 0.97A 4a9kB-3wkyA:
undetectable		 4a9kB-3wkyA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.68A 4p6sA-3wkyA:
9.8		 4p6sA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.78A 4p6sA-3wkyA:
9.8		 4p6sA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 361
HIS A 397
HIS A 199
ALA A 387
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
CUO  A 708 (-3.3A)
None
 0.90A 4p6sA-3wkyA:
9.8		 4p6sA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		6 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.75A 4p6sB-3wkyA:
9.9		 4p6sB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.75A 4p6sB-3wkyA:
9.9		 4p6sB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_B_DAHB305_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 361
HIS A 357
HIS A 203
HIS A 199
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
 0.99A 4p6sB-3wkyA:
9.9		 4p6sB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 LEU A  57
ALA A 115
THR A 119
ILE A  88
 None
 0.96A 4xe3B-3wkyA:
undetectable		 4xe3B-3wkyA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 GLY A 633
LEU A 419
PHE A 593
MET A 595
LEU A 524
 None
 1.46A 4xldA-3wkyA:
undetectable		 4xldA-3wkyA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XZK_A_AG2A700_1
(PUTATIVE
NAD(+)--ARGININE
ADP-RIBOSYLTRANSFERA
SE VIS)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 SER A 617
ARG A 547
SER A 552
GLU A 529
 None
 1.24A 4xzkA-3wkyA:
undetectable		 4xzkA-3wkyA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 6 VAL A 107
HIS A 106
LEU A  61
LEU A  53
 None
 0.95A 5hrqB-3wkyA:
undetectable
5hrqI-3wkyA:
undetectable
5hrqJ-3wkyA:
undetectable		 5hrqB-3wkyA:
6.13
5hrqI-3wkyA:
2.92
5hrqJ-3wkyA:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 SER A 556
SER A 616
SER A 573
SER A 552
 None
 1.28A 5hswA-3wkyA:
undetectable		 5hswA-3wkyA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 SER A 556
SER A 616
SER A 573
SER A 553
 None
 1.25A 5hswA-3wkyA:
undetectable		 5hswA-3wkyA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.69A 5i3aA-3wkyA:
9.9		 5i3aA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.77A 5i3aA-3wkyA:
9.9		 5i3aA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.71A 5i3aB-3wkyA:
9.9		 5i3aB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.76A 5i3aB-3wkyA:
9.9		 5i3aB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		7 / 7 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.70A 5i3bA-3wkyA:
10.1		 5i3bA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 357
HIS A 361
HIS A 199
HIS A 203
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
 0.80A 5i3bA-3wkyA:
10.1		 5i3bA-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 5 HIS A 199
HIS A 203
HIS A 361
VAL A 384
ALA A 387
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.2A)
None
None
 0.76A 5i3bB-3wkyA:
9.9		 5i3bB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 361
HIS A 397
HIS A 199
ALA A 387
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
CUO  A 708 (-3.3A)
None
 0.97A 5i3bB-3wkyA:
9.9		 5i3bB-3wkyA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 LYS A 476
ILE A 475
HIS A 474
VAL A 473
 None
 0.92A 5jmnA-3wkyA:
undetectable		 5jmnA-3wkyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.65A 5m8nA-3wkyA:
8.9		 5m8nA-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 1.01A 5m8nA-3wkyA:
8.9		 5m8nA-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.68A 5m8nB-3wkyA:
7.3		 5m8nB-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 1.04A 5m8nB-3wkyA:
7.3		 5m8nB-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 10 HIS A 357
HIS A 361
HIS A 199
HIS A 203
LEU A 204
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
 0.95A 5m8nB-3wkyA:
7.3		 5m8nB-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 9 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.65A 5m8nC-3wkyA:
8.8		 5m8nC-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 9 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.99A 5m8nC-3wkyA:
8.8		 5m8nC-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 9 HIS A 203
TYR A 208
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 1.05A 5m8nD-3wkyA:
8.5		 5m8nD-3wkyA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 7 HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.69A 5m8rA-3wkyA:
8.4		 5m8rA-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 HIS A 361
HIS A 199
HIS A 203
LEU A 204
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
 1.01A 5m8rA-3wkyA:
8.4		 5m8rA-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 8 HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.70A 5m8rB-3wkyA:
8.8		 5m8rB-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 8 HIS A 361
HIS A 199
HIS A 203
LEU A 204
 CUO  A 708 (-3.2A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
 1.01A 5m8rB-3wkyA:
8.8		 5m8rB-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		6 / 8 HIS A 203
HIS A 357
ASN A 358
HIS A 361
GLY A 382
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
None
 0.71A 5m8rC-3wkyA:
8.6		 5m8rC-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 8 HIS A 203
HIS A 357
ASN A 358
HIS A 361
VAL A 384
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
None
 0.71A 5m8rD-3wkyA:
8.6		 5m8rD-3wkyA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 ILE A 423
ILE A 538
MET A 501
ILE A 545
 None
 0.93A 5murB-3wkyA:
undetectable		 5murB-3wkyA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 12 PHE A  72
GLY A 365
LEU A 297
ILE A 283
HIS A 357
 CUO  A 708 (-4.6A)
None
None
None
CUO  A 708 (-3.3A)
 1.27A 5y2tA-3wkyA:
undetectable		 5y2tA-3wkyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.79A 5z0fA-3wkyA:
10.2
5z0fB-3wkyA:
undetectable		 5z0fA-3wkyA:
8.13
5z0fB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.77A 5z0gA-3wkyA:
10.2
5z0gB-3wkyA:
undetectable		 5z0gA-3wkyA:
8.13
5z0gB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.75A 5z0hA-3wkyA:
10.5
5z0hB-3wkyA:
undetectable		 5z0hA-3wkyA:
8.13
5z0hB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.76A 5z0iA-3wkyA:
10.5
5z0iB-3wkyA:
undetectable		 5z0iA-3wkyA:
8.13
5z0iB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.74A 5z0jA-3wkyA:
10.1
5z0jB-3wkyA:
undetectable		 5z0jA-3wkyA:
8.13
5z0jB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.72A 5z0kA-3wkyA:
10.5
5z0kB-3wkyA:
undetectable		 5z0kA-3wkyA:
8.13
5z0kB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.75A 5z0lA-3wkyA:
10.5
5z0lB-3wkyA:
undetectable		 5z0lA-3wkyA:
8.13
5z0lB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 199
HIS A 203
HIS A 357
ASN A 358
HIS A 361
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
None
CUO  A 708 (-3.2A)
 0.81A 5z0mA-3wkyA:
10.4
5z0mB-3wkyA:
undetectable		 5z0mA-3wkyA:
8.43
5z0mB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		5 / 11 HIS A 357
HIS A 226
HIS A 199
VAL A 380
ASP A 390
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
None
None
 1.39A 5z0mA-3wkyA:
10.4
5z0mB-3wkyA:
undetectable		 5z0mA-3wkyA:
8.43
5z0mB-3wkyA:
8.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		3 / 3 HIS A 357
HIS A 361
HIS A 397
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
 0.16A 5zrdA-3wkyA:
8.7		 5zrdA-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
PHE A 222
HIS A 226
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
None
CUO  A 708 (-3.3A)
 0.79A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
PHE A 393
HIS A 397
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-4.5A)
CUO  A 708 (-3.4A)
 0.24A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 397
HIS A 357
PHE A  72
HIS A 361
 CUO  A 708 (-3.4A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.6A)
CUO  A 708 (-3.2A)
 1.04A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
HIS A 226
PHE A 393
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.5A)
 0.74A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 203
HIS A 226
HIS A 199
PHE A  72
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.6A)
 1.21A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
HIS A 397
PHE A 222
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
None
 0.95A 5zrdB-3wkyA:
3.6		 5zrdB-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
HIS A 226
PHE A 393
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.5A)
 0.83A 5zrdC-3wkyA:
3.5		 5zrdC-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 203
HIS A 226
HIS A 199
PHE A  72
 CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.6A)
 1.23A 5zrdC-3wkyA:
3.5		 5zrdC-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
HIS A 397
PHE A 222
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
None
 1.00A 5zrdC-3wkyA:
3.5		 5zrdC-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 199
HIS A 203
HIS A 226
PHE A 393
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.5A)
CUO  A 708 (-3.3A)
CUO  A 708 (-4.5A)
 0.74A 5zrdD-3wkyA:
4.2		 5zrdD-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 HIS A 357
HIS A 361
HIS A 397
PHE A 222
 CUO  A 708 (-3.3A)
CUO  A 708 (-3.2A)
CUO  A 708 (-3.4A)
None
 0.97A 5zrdD-3wkyA:
4.2		 5zrdD-3wkyA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 5 ILE A 554
PHE A 618
ASN A 402
TYR A 223
 None
 1.21A 6a93B-3wkyA:
undetectable		 6a93B-3wkyA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3wky PROPHENOLOXIDASE B
(Marsupenaeus
japonicus) 		4 / 7 THR A 528
ARG A 547
HIS A 548
ASP A 531
 None
 1.33A 6mn4E-3wkyA:
undetectable		 6mn4E-3wkyA:
15.50