SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wl1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 5 GLU A 184
THR A 186
HIS A 213
LEU A 367
 None
 1.28A 1d4fC-3wl1A:
undetectable		 1d4fC-3wl1A:
20.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 9 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 501 (-3.7A)
 0.98A 1e9lA-3wl1A:
53.8		 1e9lA-3wl1A:
37.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 1jffB-3wl1A:
undetectable		 1jffB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_A_LYAA317_1
(THYMIDYLATE SYNTHASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 11 PHE A  85
LEU A 143
GLY A 142
PHE A 140
ALA A 187
 None
 1.16A 1ju6A-3wl1A:
undetectable		 1ju6A-3wl1A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 11 PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.84A 2a3aA-3wl1A:
11.1		 2a3aA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  30
PHE A  61
GLY A 106
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.63A 2a3aA-3wl1A:
11.1		 2a3aA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1433_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A  30
PHE A  61
GLY A 106
TRP A 107
GLU A 148
MET A 215
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 0.64A 2a3aA-3wl1A:
11.1		 2a3aA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 107
GLU A 148
TYR A 149
 NAG  A 505 ( 3.4A)
NAG  A 501 (-2.7A)
None
 0.42A 2a3aA-3wl1A:
11.0		 2a3aA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2433_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 9 PHE A  61
GLY A 106
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.54A 2a3aB-3wl1A:
44.1		 2a3aB-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 11 PHE A  61
GLY A 106
TRP A 107
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.72A 2a3bA-3wl1A:
44.1		 2a3bA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A  30
PHE A  61
GLY A 106
GLU A 148
MET A 215
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 0.84A 2a3bA-3wl1A:
44.1		 2a3bA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1435_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 11 TYR A  30
PHE A  61
GLY A 106
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.66A 2a3bA-3wl1A:
44.1		 2a3bA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 10 PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 1.00A 2a3bB-3wl1A:
11.0		 2a3bB-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2435_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 10 PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.86A 2a3bB-3wl1A:
11.0		 2a3bB-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TYR A  30
TRP A  34
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 503 ( 4.0A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 1.08A 2a3cA-3wl1A:
10.9		 2a3cA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TYR A  30
TRP A  34
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 503 ( 4.0A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 501 (-3.7A)
 0.97A 2a3cA-3wl1A:
10.9		 2a3cA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1434_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TYR A  30
TRP A  34
PHE A  61
GLY A 106
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 503 ( 4.0A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.70A 2a3cA-3wl1A:
10.9		 2a3cA-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 12 TRP A  34
PHE A  61
GLY A 106
ASP A 146
GLU A 148
MET A 215
TYR A 217
TRP A 372
 NAG  A 503 ( 4.0A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 1.01A 2a3cB-3wl1A:
8.9		 2a3cB-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2433_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 12 TRP A  34
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 503 ( 4.0A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.85A 2a3cB-3wl1A:
8.9		 2a3cB-3wl1A:
27.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2hxfB-3wl1A:
undetectable		 2hxfB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2hxhB-3wl1A:
undetectable		 2hxhB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2p4nB-3wl1A:
undetectable		 2p4nB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 9 TYR A  30
PHE A  61
GLY A 106
ASP A 146
GLU A 148
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 0.44A 2uy4A-3wl1A:
19.7		 2uy4A-3wl1A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 2wbeB-3wl1A:
undetectable		 2wbeB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
GLU A 148
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 0.75A 2xtkA-3wl1A:
21.0		 2xtkA-3wl1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 10 TYR A  30
PHE A  61
GLY A 106
ASP A 146
GLU A 148
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 0.61A 2xtkB-3wl1A:
20.9		 2xtkB-3wl1A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 8 VAL A 229
ASP A 239
GLY A 334
HIS A 238
 None
 0.88A 3af0A-3wl1A:
undetectable		 3af0A-3wl1A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 6 TRP A 107
ASP A 218
TRP A 223
ARG A 274
 NAG  A 505 ( 3.4A)
NAG  A 501 ( 3.2A)
NAG  A 505 (-4.0A)
NAG  A 505 ( 3.6A)
 0.77A 3arqA-3wl1A:
41.1		 3arqA-3wl1A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 7 TRP A 107
ASP A 218
TRP A 223
ARG A 274
 NAG  A 505 ( 3.4A)
NAG  A 501 ( 3.2A)
NAG  A 505 (-4.0A)
NAG  A 505 ( 3.6A)
 0.81A 3arrA-3wl1A:
41.1		 3arrA-3wl1A:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.19A 3dcoB-3wl1A:
undetectable		 3dcoB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.18A 3edlB-3wl1A:
2.7		 3edlB-3wl1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 11 PHE A  61
GLY A 106
TRP A 107
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.66A 3g6mA-3wl1A:
9.6		 3g6mA-3wl1A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		7 / 11 TYR A  30
PHE A  61
GLY A 106
ASP A 146
MET A 215
TYR A 217
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-3.0A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 (-3.7A)
 0.96A 3g6mA-3wl1A:
9.6		 3g6mA-3wl1A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA1_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		9 / 11 TYR A  30
PHE A  61
GLY A 106
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
TRP A 372
 NAG  A 501 (-3.8A)
NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 501 (-3.7A)
 0.70A 3g6mA-3wl1A:
9.6		 3g6mA-3wl1A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G6M_A_CFFA427_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A 107
TYR A 149
MET A 215
ASP A 218
TRP A 223
 NAG  A 505 ( 3.4A)
None
NAG  A 501 (-3.5A)
NAG  A 501 ( 3.2A)
NAG  A 505 (-4.0A)
 0.76A 3g6mA-3wl1A:
10.3		 3g6mA-3wl1A:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
None
NAG  A 503 ( 4.5A)
None
None
 0.97A 3g88A-3wl1A:
undetectable		 3g88A-3wl1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
None
NAG  A 503 ( 4.5A)
None
None
 0.95A 3g88B-3wl1A:
undetectable		 3g88B-3wl1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
None
NAG  A 503 ( 4.5A)
None
None
 0.97A 3g89A-3wl1A:
undetectable		 3g89A-3wl1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G89_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 11 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
None
NAG  A 503 ( 4.5A)
None
None
 0.97A 3g89B-3wl1A:
undetectable		 3g89B-3wl1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_A_SAMA303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
None
NAG  A 503 ( 4.5A)
None
None
 0.98A 3g8bA-3wl1A:
undetectable		 3g8bA-3wl1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8B_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 GLY A 298
GLY A 296
ALA A 306
ALA A 301
GLU A 314
 None
None
NAG  A 503 ( 4.5A)
None
None
 0.96A 3g8bB-3wl1A:
undetectable		 3g8bB-3wl1A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 12 VAL A 118
LEU A 209
LEU A 185
THR A 186
GLY A 105
 None
 1.17A 3iz0B-3wl1A:
undetectable		 3iz0B-3wl1A:
18.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA501_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		11 / 11 PHE A  61
GLY A 106
TRP A 107
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
ARG A 274
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 505 ( 3.6A)
NAG  A 501 (-3.7A)
 0.21A 3wqvA-3wl1A:
70.1		 3wqvA-3wl1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQV_A_GCSA502_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 4 TRP A  34
GLY A 106
TRP A 107
ALA A 108
 NAG  A 503 ( 4.0A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 502 (-3.4A)
 0.17A 3wqvA-3wl1A:
47.8		 3wqvA-3wl1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA501_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		11 / 11 PHE A  61
GLY A 106
TRP A 107
ASP A 146
GLU A 148
MET A 215
TYR A 217
ASP A 218
TYR A 272
ARG A 274
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 501 (-3.0A)
NAG  A 501 (-2.7A)
NAG  A 501 (-3.5A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 502 (-3.9A)
NAG  A 505 ( 3.6A)
NAG  A 501 (-3.7A)
 0.23A 3wqwA-3wl1A:
70.5		 3wqwA-3wl1A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WQW_A_GCSA502_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 5 TRP A  34
GLY A 106
TRP A 107
ALA A 108
PHE A 309
 NAG  A 503 ( 4.0A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 502 (-3.4A)
NAG  A 502 (-3.3A)
 0.79A 3wqwA-3wl1A:
70.5		 3wqwA-3wl1A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		3 / 3 PHE A 379
TYR A 303
TYR A 313
 None
 1.10A 4ffwA-3wl1A:
undetectable		 4ffwA-3wl1A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		3 / 3 LYS A 164
TYR A 167
ARG A 124
 None
 1.01A 4gc9A-3wl1A:
undetectable		 4gc9A-3wl1A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		3 / 3 ASP A 375
TYR A  44
TRP A  34
 None
None
NAG  A 503 ( 4.0A)
 1.30A 4p7nA-3wl1A:
18.8		 4p7nA-3wl1A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		6 / 12 TYR A  30
LEU A 367
VAL A 267
GLY A 368
ALA A 369
LEU A 393
 NAG  A 501 (-3.8A)
None
None
None
None
None
 1.33A 4rrxA-3wl1A:
undetectable		 4rrxA-3wl1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		6 / 12 TYR A  30
LEU A 367
VAL A 267
GLY A 368
ALA A 369
LEU A 393
 NAG  A 501 (-3.8A)
None
None
None
None
None
 1.33A 4rrxB-3wl1A:
undetectable		 4rrxB-3wl1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 8 HIS A 230
GLU A 349
ARG A 220
PRO A 337
 None
 1.19A 4uhxA-3wl1A:
undetectable		 4uhxA-3wl1A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 8 HIS A 230
GLU A 349
ARG A 220
PRO A 337
 None
 1.19A 4uhxA-3wl1A:
undetectable		 4uhxA-3wl1A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 5 LEU A 172
ALA A 187
VAL A 102
ILE A  58
 None
 0.93A 4xe3A-3wl1A:
undetectable		 4xe3A-3wl1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 5 LEU A 172
ALA A 187
VAL A 102
ILE A  58
 None
 0.93A 4xe3B-3wl1A:
undetectable		 4xe3B-3wl1A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		3 / 3 TRP A 107
GLU A 148
ASP A 218
 NAG  A 505 ( 3.4A)
NAG  A 501 (-2.7A)
NAG  A 501 ( 3.2A)
 0.41A 5gqbA-3wl1A:
43.1		 5gqbA-3wl1A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		8 / 8 PHE A  61
GLY A 106
TRP A 107
GLU A 148
TYR A 217
ASP A 218
ARG A 274
TRP A 372
 NAG  A 501 (-4.5A)
NAG  A 501 (-3.6A)
NAG  A 505 ( 3.4A)
NAG  A 501 (-2.7A)
NAG  A 501 (-4.6A)
NAG  A 501 ( 3.2A)
NAG  A 505 ( 3.6A)
NAG  A 501 (-3.7A)
 0.52A 5gqbA-3wl1A:
43.0		 5gqbA-3wl1A:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 5 GLU A  66
GLY A 110
SER A 112
GLY A 156
 None
 0.96A 5kprA-3wl1A:
1.0		 5kprA-3wl1A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		3 / 3 GLU A 244
TYR A 243
ARG A 220
 None
 0.77A 5uunB-3wl1A:
undetectable		 5uunB-3wl1A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 10 LEU A 145
VAL A 128
VAL A 118
TYR A 114
LEU A 143
 None
 1.43A 6bsgA-3wl1A:
undetectable		 6bsgA-3wl1A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 10 LEU A 145
VAL A 128
VAL A 118
TYR A 114
LEU A 143
 None
 1.45A 6bsiA-3wl1A:
undetectable		 6bsiA-3wl1A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		5 / 10 LEU A 145
VAL A 128
VAL A 118
TYR A 114
LEU A 143
 None
 1.42A 6bsjA-3wl1A:
undetectable		 6bsjA-3wl1A:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 6 ASP A 218
TYR A 149
GLU A 148
ASP A 146
 NAG  A 501 ( 3.2A)
None
NAG  A 501 (-2.7A)
NAG  A 501 (-3.0A)
 1.41A 6mn5A-3wl1A:
undetectable		 6mn5A-3wl1A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3wl1 CHITINASE
(Ostrinia
furnacalis) 		4 / 6 ASP A 218
TYR A 149
GLU A 148
ASP A 146
 NAG  A 501 ( 3.2A)
None
NAG  A 501 (-2.7A)
NAG  A 501 (-3.0A)
 1.43A 6mn5C-3wl1A:
undetectable		 6mn5C-3wl1A:
14.71