SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wlw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3wlw ANTIBODY L CHAIN
(Homo
sapiens) 		3 / 3 SER L 180
VAL L 118
LEU L 139
 None
 0.62A 1yajG-3wlwL:
undetectable		 1yajG-3wlwL:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3wlw ANTIBODY L CHAIN
(Homo
sapiens) 		5 / 12 SER L  11
VAL L  10
PHE L  64
ILE L  77
HIS L  41
 None
 1.33A 2vdyB-3wlwL:
undetectable		 2vdyB-3wlwL:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3wlw ANTIBODY L CHAIN
(Homo
sapiens) 		5 / 12 SER L  11
VAL L  10
PHE L  64
ILE L  77
HIS L  41
 None
 1.39A 4c49B-3wlwL:
undetectable		 4c49B-3wlwL:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3wlw ANTIBODY L CHAIN
(Homo
sapiens) 		5 / 12 GLY L 131
LEU L 184
SER L 134
ASP L 188
ALA L 187
 None
 1.09A 4krhA-3wlwL:
undetectable		 4krhA-3wlwL:
19.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 3wlw ANTIBODY L CHAIN
(Homo
sapiens) 		5 / 7 TYR L  34
SER L  36
TYR L  38
TYR L  51
PRO L  57
 None
 0.70A 5aclA-3wlwL:
20.8		 5aclA-3wlwL:
82.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 3wlw ANTIBODY L CHAIN
(Homo
sapiens) 		4 / 8 SER L  36
TYR L  38
SER L  97
PHE L 101
 None
 0.77A 5alcL-3wlwL:
21.0		 5alcL-3wlwL:
53.85