SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wmd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 12 TRP A 100
GLY A 136
THR A 137
ALA A 116
GLY A  40
 None
 0.92A 1nbiC-3wmdA:
undetectable		 1nbiC-3wmdA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 12 TRP A 100
GLY A 136
THR A 137
ALA A 116
GLY A  40
 None
 0.93A 1nbiD-3wmdA:
undetectable		 1nbiD-3wmdA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 10 ILE A  17
ILE A  25
ASP A  37
SER A 133
SER A  84
 None
 1.24A 3o1xA-3wmdA:
undetectable		 3o1xA-3wmdA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 10 ILE A  17
ILE A  25
ASP A  37
SER A 133
SER A  84
 None
 1.24A 3qgzA-3wmdA:
undetectable		 3qgzA-3wmdA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 12 TYR A  54
HIS A  13
LEU A  35
ALA A  30
TYR A  29
 None
 1.14A 3vw7A-3wmdA:
undetectable		 3vw7A-3wmdA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 12 LEU A  62
ILE A  25
HIS A  53
ASP A  37
SER A 133
 None
 1.32A 4r88A-3wmdA:
undetectable		 4r88A-3wmdA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WW7_A_ACTA305_0
(EKC/KEOPS COMPLEX
SUBUNIT BUD32)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		4 / 6 LEU A  58
LEU A  62
ASN A  18
ILE A  17
 None
 0.94A 4ww7A-3wmdA:
0.1		 4ww7A-3wmdA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		5 / 12 HIS A  13
ILE A  17
LEU A  35
LEU A  50
TYR A  29
 None
 1.31A 4xumA-3wmdA:
undetectable		 4xumA-3wmdA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 3wmd PROBABLE MONENSIN
BIOSYNTHESIS
ISOMERASE
(Streptomyces
cinnamonensis) 		4 / 4 VAL A  85
LEU A  62
LEU A  57
ASP A  37
 None
 1.09A 5xv7A-3wmdA:
undetectable		 5xv7A-3wmdA:
17.75