SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 ALA A 245
VAL A 228
TRP A 289
 None
 0.95A 1gmkA-3wmyA:
undetectable
1gmkB-3wmyA:
undetectable		 1gmkA-3wmyA:
2.84
1gmkB-3wmyA:
2.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 GLN A 373
TYR A 182
ARG A 183
 None
 0.63A 1gtbA-3wmyA:
undetectable		 1gtbA-3wmyA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 6 TRP A 466
GLU A 379
TYR A 224
GLY A 225
 None
None
TRS  A 503 (-3.8A)
None
 0.90A 1maaB-3wmyA:
undetectable
1maaD-3wmyA:
undetectable		 1maaB-3wmyA:
23.13
1maaD-3wmyA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 6 TRP A 197
GLY A 242
PHE A 229
SER A 230
 None
 0.96A 2a3cA-3wmyA:
undetectable		 2a3cA-3wmyA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 6 TRP A 197
GLY A 242
PHE A 229
SER A 230
 None
 0.94A 2a3cB-3wmyA:
undetectable		 2a3cB-3wmyA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 8 SER A 217
TYR A 224
TYR A 461
HIS A 427
 TRS  A 503 ( 4.5A)
TRS  A 503 (-3.8A)
TRS  A 503 (-4.9A)
CA  A 501 ( 3.6A)
 1.20A 2bteA-3wmyA:
undetectable		 2bteA-3wmyA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 8 SER A 217
TYR A 224
TYR A 461
HIS A 427
 TRS  A 503 ( 4.5A)
TRS  A 503 (-3.8A)
TRS  A 503 (-4.9A)
CA  A 501 ( 3.6A)
 1.26A 2bteD-3wmyA:
undetectable		 2bteD-3wmyA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 SER A 217
THR A 311
GLN A 364
 TRS  A 503 ( 4.5A)
None
CA  A 501 (-2.9A)
 0.82A 2fk8A-3wmyA:
undetectable		 2fk8A-3wmyA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 GLN A 192
THR A 422
TRP A 466
 None
 1.08A 2rctA-3wmyA:
undetectable		 2rctA-3wmyA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 10 LEU A 178
LEU A 446
VAL A 441
SER A 390
ILE A 377
 None
 0.98A 2w9gA-3wmyA:
undetectable		 2w9gA-3wmyA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 10 PHE A 323
ALA A 252
PHE A 275
LEU A 295
THR A 254
 None
TRS  A 503 ( 4.1A)
None
None
None
 1.22A 3a3yA-3wmyA:
undetectable		 3a3yA-3wmyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 11 LEU A 178
LEU A 446
VAL A 441
SER A 390
ILE A 377
 None
 0.96A 3frbX-3wmyA:
undetectable		 3frbX-3wmyA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 9 LEU A 178
LEU A 446
VAL A 441
SER A 390
ILE A 377
 None
 0.97A 3freX-3wmyA:
undetectable		 3freX-3wmyA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 GLU A 361
GLU A 379
TRP A 466
 TRS  A 503 (-2.9A)
None
None
 1.22A 3hrdA-3wmyA:
undetectable
3hrdE-3wmyA:
undetectable
3hrdF-3wmyA:
undetectable		 3hrdA-3wmyA:
21.58
3hrdE-3wmyA:
21.58
3hrdF-3wmyA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEK_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.43A 3mekA-3wmyA:
undetectable		 3mekA-3wmyA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QWP_A_SAMA510_0
(SET AND MYND
DOMAIN-CONTAINING
PROTEIN 3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.44A 3qwpA-3wmyA:
undetectable		 3qwpA-3wmyA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 PHE A 256
GLN A 364
PHE A 340
 None
CA  A 501 (-2.9A)
None
 0.73A 3rv5A-3wmyA:
undetectable		 3rv5A-3wmyA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 7 ASN A 416
ALA A 412
ARG A 389
ALA A 404
 None
 1.14A 3twpB-3wmyA:
undetectable		 3twpB-3wmyA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 ASN A 343
PHE A 275
TYR A 268
 None
 0.74A 4u15A-3wmyA:
undetectable		 4u15A-3wmyA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCL_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.24A 5cclA-3wmyA:
undetectable		 5cclA-3wmyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CCM_A_SAMA504_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.41A 5ccmA-3wmyA:
undetectable		 5ccmA-3wmyA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HSW_A_ACTA501_0
(ORF 37)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 5 SER A 220
SER A 219
SER A 223
SER A 463
 None
 1.26A 5hswA-3wmyA:
undetectable		 5hswA-3wmyA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.46A 5wz1A-3wmyA:
undetectable		 5wz1A-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.44A 5wz1B-3wmyA:
undetectable		 5wz1B-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.43A 5wz1C-3wmyA:
undetectable		 5wz1C-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.45A 5wz1D-3wmyA:
undetectable		 5wz1D-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.44A 5wz1E-3wmyA:
undetectable		 5wz1E-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.43A 5wz1F-3wmyA:
undetectable		 5wz1F-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.46A 5wz1G-3wmyA:
undetectable		 5wz1G-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		6 / 12 GLY A 382
GLY A 385
HIS A 427
GLU A 361
ASP A 429
ILE A 377
 None
None
CA  A 501 ( 3.6A)
TRS  A 503 (-2.9A)
None
None
 1.42A 5wz1H-3wmyA:
undetectable		 5wz1H-3wmyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXG_A_SAMA502_0
(SMYD3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.40A 5xxgA-3wmyA:
undetectable		 5xxgA-3wmyA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXJ_A_SAMA505_0
(SMYD3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.46A 5xxjA-3wmyA:
undetectable		 5xxjA-3wmyA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJO_A_SAMA505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SMYD3)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		5 / 12 ARG A 386
GLY A 382
ASN A 384
ASN A 416
PHE A 388
 None
 1.40A 5yjoA-3wmyA:
undetectable		 5yjoA-3wmyA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DHB_A_BEZA202_0
(HEPATITIS A VIRUS
CELLULAR RECEPTOR 2)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		4 / 6 ILE A 337
MET A 319
ASN A 318
ASP A 315
 None
 1.30A 6dhbA-3wmyA:
undetectable		 6dhbA-3wmyA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wmy EXTRACELLULAR
EXO-ALPHA-L-ARABINOF
URANOSIDASE
(Streptomyces
coelicolor) 		3 / 3 ARG A 432
PHE A 322
PHE A 256
 None
 1.04A 6nknC-3wmyA:
undetectable
6nknJ-3wmyA:
undetectable		 6nknC-3wmyA:
21.51
6nknJ-3wmyA:
7.66