SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		6 / 12 TYR A  76
ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 GOL  A 505 (-3.9A)
None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.71A 1dedB-3wn6A:
28.4		 1dedB-3wn6A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 7 GLY A 155
PRO A 153
ASP A 166
ALA A 168
 None
None
CA  A 502 (-3.0A)
None
 0.79A 1gxsA-3wn6A:
undetectable
1gxsB-3wn6A:
undetectable		 1gxsA-3wn6A:
21.07
1gxsB-3wn6A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 11 LEU A 388
GLU A 406
VAL A 405
ILE A 409
HIS A 339
 None
 1.36A 1mrqA-3wn6A:
4.9		 1mrqA-3wn6A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 11 LEU A 388
TYR A 387
GLU A 406
VAL A 405
ILE A 409
 None
 1.30A 1mrqA-3wn6A:
4.9		 1mrqA-3wn6A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		10 / 12 TRP A  34
TYR A  76
HIS A 117
ARG A 201
ASP A 203
LYS A 206
GLU A 228
TRP A 230
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.9A)
None
None
GOL  A 505 (-3.4A)
None
None
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.37A 1mxdA-3wn6A:
40.8		 1mxdA-3wn6A:
27.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		3 / 3 PHE A 197
TYR A  44
TYR A  89
 None
 0.87A 1x70B-3wn6A:
undetectable		 1x70B-3wn6A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 5 GLY A  31
GLN A  30
TRP A  63
SER A  36
 None
 1.15A 1zzuA-3wn6A:
0.6		 1zzuA-3wn6A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 5 LEU A 377
PRO A 296
ALA A 295
ILE A 379
 None
 0.92A 2aofB-3wn6A:
undetectable		 2aofB-3wn6A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 9 TYR A 208
LEU A 141
LEU A 184
HIS A 175
LEU A 188
 None
 1.23A 2bxeA-3wn6A:
undetectable		 2bxeA-3wn6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ILE A 336
VAL A 310
HIS A 349
ALA A 280
VAL A 329
 None
 1.32A 2g72B-3wn6A:
undetectable		 2g72B-3wn6A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 11 LEU A 377
VAL A 395
ILE A 365
ALA A 389
ILE A 391
 None
 0.77A 2idwA-3wn6A:
undetectable		 2idwA-3wn6A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 11 VAL A 395
ILE A 365
ILE A 336
ALA A 389
ILE A 391
 None
 0.87A 2idwA-3wn6A:
undetectable		 2idwA-3wn6A:
14.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QPU_B_QPSB3000_1
(ALPHA-AMYLASE TYPE A
ISOZYME)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		7 / 9 LYS A 398
TYR A 403
ASP A 404
VAL A 405
HIS A 418
ALA A 423
TRP A 425
 None
 1.15A 2qpuB-3wn6A:
68.0		 2qpuB-3wn6A:
76.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 GLY A  58
ASP A  52
VAL A  51
GLY A 106
ILE A  54
 None
 1.04A 2z54A-3wn6A:
undetectable		 2z54A-3wn6A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.63A 3aicA-3wn6A:
10.2		 3aicA-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.60A 3aicB-3wn6A:
6.4		 3aicB-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		6 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
TYR A  76
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
GOL  A 505 (-3.9A)
 0.61A 3aicC-3wn6A:
10.3		 3aicC-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.70A 3aicD-3wn6A:
10.3		 3aicD-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.65A 3aicE-3wn6A:
10.4		 3aicE-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.62A 3aicF-3wn6A:
10.2		 3aicF-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.60A 3aicG-3wn6A:
10.3		 3aicG-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.69A 3aicH-3wn6A:
10.2		 3aicH-3wn6A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 GLY A  58
ASP A  52
VAL A  51
GLY A 106
ILE A  54
 None
 1.08A 3d1zB-3wn6A:
undetectable		 3d1zB-3wn6A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 9 LEU A 377
VAL A 395
ILE A 365
ILE A 336
ILE A 391
 None
 1.02A 3ekqB-3wn6A:
undetectable		 3ekqB-3wn6A:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 9 LEU A 377
VAL A 395
ILE A 365
ALA A 389
ILE A 391
 None
 0.72A 3el0B-3wn6A:
undetectable		 3el0B-3wn6A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 9 VAL A 395
ILE A 365
ILE A 336
ALA A 389
ILE A 391
 None
 0.89A 3el0B-3wn6A:
undetectable		 3el0B-3wn6A:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 LEU A  98
GLY A 196
LEU A  64
PRO A  67
TYR A  44
 None
 1.21A 3mecA-3wn6A:
undetectable		 3mecA-3wn6A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 8 HIS A 103
LEU A  84
TRP A 190
ASP A 194
 None
 1.26A 3n2oC-3wn6A:
5.9
3n2oD-3wn6A:
2.4		 3n2oC-3wn6A:
20.28
3n2oD-3wn6A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 5 GLU A  39
GLY A  42
TYR A  44
GLN A  94
 None
 1.00A 3w9tD-3wn6A:
undetectable		 3w9tD-3wn6A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 5 GLU A  39
GLY A  42
TYR A  44
GLN A  94
 None
 1.05A 3w9tE-3wn6A:
undetectable		 3w9tE-3wn6A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 5 GLU A  39
GLY A  42
TYR A  44
GLN A  94
 None
 1.03A 3w9tG-3wn6A:
undetectable		 3w9tG-3wn6A:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 10 TRP A 425
VAL A 415
ILE A 424
LEU A 386
LEU A 388
 None
 1.39A 4jtqA-3wn6A:
9.6		 4jtqA-3wn6A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ALA A 280
ILE A 396
LEU A 377
ARG A 378
GLY A 393
 None
 1.34A 4l9qA-3wn6A:
undetectable		 4l9qA-3wn6A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LJ0_A_ACTA505_0
(NAB2)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		3 / 3 LEU A 277
LYS A 274
THR A 273
 None
 0.46A 4lj0A-3wn6A:
undetectable		 4lj0A-3wn6A:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 11 TYR A 216
HIS A 117
HIS A 175
LEU A 184
LEU A 188
 None
 1.32A 4m7tA-3wn6A:
2.7		 4m7tA-3wn6A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 ARG A 201
ASP A 203
GLU A 228
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.4A)
None
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.41A 5csyB-3wn6A:
4.3		 5csyB-3wn6A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HES_A_032A401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE MLT)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		6 / 12 ILE A 299
ILE A 276
THR A 273
ALA A 306
ASP A 257
GLY A 290
 None
None
None
None
TAR  A 507 ( 4.5A)
None
 1.31A 5hesA-3wn6A:
undetectable		 5hesA-3wn6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 9 LEU A 377
VAL A 395
ILE A 365
ILE A 336
ILE A 391
 None
 1.12A 5kqxB-3wn6A:
undetectable		 5kqxB-3wn6A:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LOG_A_LDPA1004_1
(PUTATIVE
O-METHYLTRANSFERASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 6 ASP A 352
ASP A 348
ASN A  33
TRP A  43
 None
 1.48A 5logA-3wn6A:
undetectable		 5logA-3wn6A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		3 / 3 THR A 273
THR A 267
LEU A  28
 None
 0.45A 5m66D-3wn6A:
undetectable		 5m66D-3wn6A:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OAJ_E_TKTE601_1
()		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		4 / 8 GLU A  39
TRP A  43
PHE A 351
TYR A 347
 None
 0.93A 5oajD-3wn6A:
undetectable
5oajE-3wn6A:
undetectable		 5oajD-3wn6A:
18.02
5oajE-3wn6A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 GLY A  58
ASP A  52
VAL A  51
GLY A 106
ILE A  54
 None
 1.02A 5t2zA-3wn6A:
undetectable		 5t2zA-3wn6A:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		5 / 12 GLY A 135
HIS A 122
ASP A  83
GLU A  92
THR A 136
 None
 1.28A 5x6yC-3wn6A:
undetectable		 5x6yC-3wn6A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		6 / 12 TRP A  34
TYR A  76
HIS A 117
ASP A 203
HIS A 313
ASP A 314
 None
GOL  A 505 (-3.9A)
None
GOL  A 505 (-3.4A)
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 0.51A 6ag0A-3wn6A:
36.3		 6ag0A-3wn6A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		6 / 12 TYR A  76
HIS A 117
GLU A 251
ASP A 203
HIS A 313
ASP A 314
 GOL  A 505 (-3.9A)
None
None
GOL  A 505 (-3.4A)
GOL  A 505 (-4.3A)
GOL  A 505 (-2.9A)
 1.33A 6ag0A-3wn6A:
36.3		 6ag0A-3wn6A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3wn6 ALPHA-AMYLASE
(Oryza
sativa) 		6 / 12 ARG A 368
GLY A 393
ILE A 409
GLY A 412
ILE A 428
VAL A 416
 None
 1.24A 6dj1B-3wn6A:
undetectable		 6dj1B-3wn6A:
12.59