SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wnv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 12 LEU A 213
ASN A 214
LEU A 160
GLY A 161
THR A 115
 None
 1.30A 1p93A-3wnvA:
undetectable		 1p93A-3wnvA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 10 ALA A 100
ILE A  72
VAL A  79
ALA A  53
LEU A   7
 None
 1.06A 1xp0A-3wnvA:
undetectable		 1xp0A-3wnvA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 12 LEU A 305
LEU A 308
ASN A 309
LEU A 311
LEU A  28
 None
 0.99A 1zucB-3wnvA:
undetectable		 1zucB-3wnvA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 12 LEU A 305
LEU A 308
ASN A 309
LEU A 311
LEU A  28
 None
 0.97A 3d90B-3wnvA:
undetectable		 3d90B-3wnvA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9R_A_ACTA700_0
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 6 GLY A 161
TYR A 182
GLY A 166
ASN A 184
 None
 1.07A 3e9rA-3wnvA:
undetectable		 3e9rA-3wnvA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 9 ALA A 286
LEU A 280
ILE A 248
LEU A 213
ILE A 239
 None
 1.27A 3jw3B-3wnvA:
undetectable		 3jw3B-3wnvA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 10 ALA A 252
ARG A 255
LEU A 230
LEU A 257
ILE A 239
 None
 0.98A 3wdmB-3wnvA:
undetectable		 3wdmB-3wnvA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 10 ALA A 252
ARG A 255
LEU A 230
LEU A 257
ILE A 239
 None
 0.88A 3wdmD-3wnvA:
3.0		 3wdmD-3wnvA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 11 VAL A 169
ALA A 116
GLY A 161
ILE A 180
GLY A 163
 None
 1.18A 3zosA-3wnvA:
undetectable
3zosB-3wnvA:
undetectable		 3zosA-3wnvA:
25.00
3zosB-3wnvA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 6 ASN A 309
GLU A 302
GLU A 304
GLU A  18
 None
 1.07A 4mi4A-3wnvA:
undetectable		 4mi4A-3wnvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 7 ASN A 309
GLU A 302
GLU A 304
GLU A  18
 None
 1.11A 4mi4B-3wnvA:
undetectable
4mi4C-3wnvA:
undetectable		 4mi4B-3wnvA:
22.42
4mi4C-3wnvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 7 ASN A 309
GLU A 302
GLU A 304
GLU A  18
 None
 1.12A 4mi4A-3wnvA:
undetectable
4mi4C-3wnvA:
undetectable		 4mi4A-3wnvA:
22.42
4mi4C-3wnvA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 8 ASN A 309
GLU A 302
GLU A 304
GLU A  18
 None
 1.09A 4mj8A-3wnvA:
undetectable
4mj8C-3wnvA:
undetectable		 4mj8A-3wnvA:
22.29
4mj8C-3wnvA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 8 ASN A 309
GLU A 302
GLU A 304
GLU A  18
 None
 1.10A 4mj8B-3wnvA:
undetectable
4mj8C-3wnvA:
undetectable		 4mj8B-3wnvA:
22.29
4mj8C-3wnvA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PE5_B_QELB920_1
(GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 1
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		5 / 10 TYR A  55
LEU A  22
ALA A  53
ILE A  54
GLU A 316
 None
 1.48A 4pe5A-3wnvA:
5.7
4pe5B-3wnvA:
6.4		 4pe5A-3wnvA:
17.13
4pe5B-3wnvA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UXQ_A_0LIA1752_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 7 VAL A 262
ILE A 248
ALA A 252
ILE A 224
 None
 0.74A 4uxqA-3wnvA:
undetectable		 4uxqA-3wnvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		4 / 6 ILE A 181
GLY A 166
ASN A 214
ILE A 180
 None
 1.00A 5j4nB-3wnvA:
undetectable		 5j4nB-3wnvA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB307_0
(WELO5)		 3wnv GLYOXYLATE REDUCTASE
(Paecilomyces
sp.
'thermophila') 		3 / 3 GLU A 203
HIS A 183
VAL A 199
 None
 0.90A 5trqB-3wnvA:
undetectable		 5trqB-3wnvA:
22.13