SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2
(Bacillus
halodurans) 		3 / 3 LEU A 236
PRO A 237
LEU A 240
 None
 0.47A 2qd5B-3wo6A:
undetectable		 2qd5B-3wo6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2
(Bacillus
halodurans) 		5 / 12 ALA A  53
GLY A  58
LEU A  55
PHE A 164
SER A  63
 None
 1.47A 3bxoB-3wo6A:
undetectable		 3bxoB-3wo6A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2
(Bacillus
halodurans) 		3 / 3 LEU A 236
PRO A 237
LEU A 240
 None
 0.53A 3hcrA-3wo6A:
undetectable		 3hcrA-3wo6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2
(Bacillus
halodurans) 		4 / 7 ILE A 249
ILE A  65
LEU A 176
VAL A 179
 None
 0.85A 3ua5B-3wo6A:
0.6		 3ua5B-3wo6A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2
(Bacillus
halodurans) 		4 / 7 THR A  79
LEU A  80
LEU A  76
THR A 255
 None
 0.90A 4z90A-3wo6A:
2.1
4z90B-3wo6A:
2.7
4z90C-3wo6A:
2.7
4z90D-3wo6A:
2.7
4z90E-3wo6A:
2.8		 4z90A-3wo6A:
19.31
4z90B-3wo6A:
19.31
4z90C-3wo6A:
19.31
4z90D-3wo6A:
19.31
4z90E-3wo6A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_1
(CYTOCHROME P450 1A1)		 3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2
(Bacillus
halodurans) 		4 / 5 ILE A  64
SER A  63
ALA A 152
LEU A 240
 None
 1.04A 6dwnA-3wo6A:
undetectable		 6dwnA-3wo6A:
13.75