SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wo9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CET_A_CLQA1001_0
(PROTEIN (L-LACTATE
DEHYDROGENASE))		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		5 / 9 VAL A 157
GLY A 156
ASP A 159
ALA A 181
PHE A 211
 None
 1.17A 1cetA-3wo9A:
undetectable		 1cetA-3wo9A:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		5 / 9 LEU A 145
LEU A 129
VAL A 109
LEU A 116
PHE A 134
 None
 1.24A 1tbfA-3wo9A:
undetectable		 1tbfA-3wo9A:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_A_HSMA145_1
(D7R4 PROTEIN)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 7 ILE A 212
TYR A 207
PHE A 182
ASP A 183
 None
 1.14A 2qebA-3wo9A:
undetectable		 2qebA-3wo9A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEB_B_HSMB145_1
(D7R4 PROTEIN)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 7 ILE A 212
TYR A 207
PHE A 182
ASP A 183
 None
 1.11A 2qebB-3wo9A:
undetectable		 2qebB-3wo9A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		5 / 12 LEU A  73
LEU A 169
ILE A 153
VAL A 133
VAL A 109
 None
 1.09A 2ygnA-3wo9A:
undetectable		 2ygnA-3wo9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA800_0
(GLUTAMATE RECEPTOR 2)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 7 ASN A  76
LEU A  73
ASP A  74
SER A  54
 None
 1.37A 3lslA-3wo9A:
undetectable
3lslD-3wo9A:
undetectable		 3lslA-3wo9A:
19.93
3lslD-3wo9A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 7 VAL A 177
LEU A 208
PHE A 158
LEU A 188
 None
 1.04A 3qeoB-3wo9A:
undetectable		 3qeoB-3wo9A:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 6 LEU A 145
PHE A 158
ALA A 181
LEU A 174
 None
 1.01A 3t3zA-3wo9A:
undetectable		 3t3zA-3wo9A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 7 TYR A  99
ASP A 123
SER A 146
TYR A 142
 None
 1.33A 4arcA-3wo9A:
undetectable		 4arcA-3wo9A:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 8 LEU A 208
VAL A 234
LEU A 167
LEU A 191
 None
 0.76A 4l1xA-3wo9A:
undetectable		 4l1xA-3wo9A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		3 / 3 ASP A  74
ARG A 120
TYR A  99
 None
 0.99A 5a7mA-3wo9A:
undetectable		 5a7mA-3wo9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		3 / 3 ASP A  74
ARG A 120
TYR A  99
 None
 1.00A 5a7mB-3wo9A:
undetectable		 5a7mB-3wo9A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 3wo9 VARIABLE LYMPHOCYTE
RECEPTOR C
(Lethenteron
camtschaticum) 		4 / 7 THR A  49
PRO A  47
THR A  43
SER A  40
 None
 1.22A 5b6iA-3wo9A:
undetectable		 5b6iA-3wo9A:
23.62