SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		4 / 5 PRO A  48
VAL A  49
GLY A  68
LYS A  66
 None
 1.06A 3elzB-3wobA:
undetectable		 3elzB-3wobA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		5 / 12 PHE A  45
GLY A  68
SER A  64
TRP A  63
GLU A  65
 None
 1.15A 4bvaA-3wobA:
undetectable		 4bvaA-3wobA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		5 / 12 PHE A  45
GLY A  68
SER A  64
TRP A  63
GLU A  65
 None
 1.15A 4bvaB-3wobA:
undetectable		 4bvaB-3wobA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		3 / 3 ARG A  58
TRP A  63
ILE A  78
 None
 1.12A 4mwxA-3wobA:
undetectable		 4mwxA-3wobA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		5 / 12 GLU A  36
PHE A  29
ILE A 142
GLY A 146
LEU A 130
 None
 1.38A 5esgA-3wobA:
undetectable		 5esgA-3wobA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		4 / 6 ILE A  86
GLY A 132
ILE A  85
TRP A 149
 None
 1.00A 5j4nB-3wobA:
undetectable		 5j4nB-3wobA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3wob HYPOTHETICAL PROTEIN
(Sus
scrofa) 		4 / 7 ILE A 142
THR A 143
TYR A  28
PHE A  29
 None
 1.03A 5zsfA-3wobA:
undetectable
5zsfB-3wobA:
undetectable		 5zsfA-3wobA:
17.99
5zsfB-3wobA:
17.99