SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3woe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DXR_A_SORA1002_0 (LACTOTRANSFERRIN)	3woe	PUTATIVE UNCHARACTERIZED PROTEIN (Thermus virus P23-45)	3 / 3	THR B 33 PRO B 36 TYR B 27	None	0.97A	2dxrA-3woeB: undetectable	2dxrA-3woeB: 12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HYT_A_OBNA1104_2 (SODIUM/POTASSIUM-TRA NSPORTING ATPASE SUBUNIT ALPHA-1)	3woe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA PUTATIVE UNCHARACTERIZED PROTEIN (Thermus thermophilus; Thermus virus P23-45)	4 / 5	PRO B 17 ASP A 738 ILE A 745 VAL A 825	None	1.30A	4hytA-3woeB: undetectable	4hytA-3woeB: 7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	3woe	PUTATIVE UNCHARACTERIZED PROTEIN (Thermus virus P23-45)	5 / 11	LEU B 54 PHE B 13 GLY B 96 GLN B 92 ALA B 90	None	1.28A	4wnuC-3woeB: undetectable	4wnuC-3woeB: 14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XQE_A_AG2A506_1 (HOMOSPERMIDINE SYNTHASE)	3woe	DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA (Thermus thermophilus)	4 / 6	ARG A 724 ARG A 735 VAL A 743 ASP A 736	None	1.42A	4xqeA-3woeA: undetectable	4xqeA-3woeA: 16.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2DXR_A_SORA1002_0","LACTOTRANSFERRIN","3woe","PUTATIVE UNCHARACTERIZED PROTEIN","Thermus virus P23-45",3,"THR B  33;PRO B  36;TYR B  27","None","0.97A","2dxrA-3woeB:undetectable","2dxrA-3woeB:12.91"],["4HYT_A_OBNA1104_2","SODIUM\/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA-1","3woe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA;PUTATIVE UNCHARACTERIZED PROTEIN","Thermus thermophilus;Thermus virus P23-45",4,"PRO B  17;ASP A 738;ILE A 745;VAL A 825","None","1.30A","4hytA-3woeB:undetectable","4hytA-3woeB:7.71"],["4WNU_C_QDNC602_1","CYTOCHROME P450 2D6","3woe","PUTATIVE UNCHARACTERIZED PROTEIN","Thermus virus P23-45",5,"LEU B  54;PHE B  13;GLY B  96;GLN B  92;ALA B  90","None","1.28A","4wnuC-3woeB:undetectable","4wnuC-3woeB:14.59"],["4XQE_A_AG2A506_1","HOMOSPERMIDINE SYNTHASE","3woe","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA","Thermus thermophilus",4,"ARG A 724;ARG A 735;VAL A 743;ASP A 736","None","1.42A","4xqeA-3woeA:undetectable","4xqeA-3woeA:16.06"]]