SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3woh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3woh SIAM
(Streptomyces
sp.
A7248) 		4 / 8 GLY A  59
THR A  60
ALA A  61
VAL A  14
 None
 0.80A 2a1hA-3wohA:
undetectable
2a1hB-3wohA:
undetectable		 2a1hA-3wohA:
20.70
2a1hB-3wohA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8L_A_SAMA400_0
(HYPOTHETICAL PROTEIN
LMO1582)		 3woh SIAM
(Streptomyces
sp.
A7248) 		5 / 12 GLY A 223
LEU A 228
ASP A 219
GLY A  22
PRO A 189
 None
 1.13A 2f8lA-3wohA:
6.4		 2f8lA-3wohA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3woh SIAM
(Streptomyces
sp.
A7248) 		5 / 12 LEU A 119
PHE A 123
LEU A 166
SER A 145
VAL A 240
 None
 1.26A 2pnjB-3wohA:
3.1		 2pnjB-3wohA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3woh SIAM
(Streptomyces
sp.
A7248) 		5 / 11 LEU A 119
PHE A 123
LEU A 166
SER A 145
VAL A 240
 None
 1.24A 2po5B-3wohA:
3.9		 2po5B-3wohA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3woh SIAM
(Streptomyces
sp.
A7248) 		4 / 7 GLU A  55
ILE A  38
ALA A 229
ILE A 142
 None
 0.78A 2xkwA-3wohA:
undetectable		 2xkwA-3wohA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3woh SIAM
(Streptomyces
sp.
A7248) 		5 / 12 LEU A 119
PHE A 123
LEU A 166
SER A 145
VAL A 240
 None
 1.27A 3aqiB-3wohA:
2.8		 3aqiB-3wohA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3woh SIAM
(Streptomyces
sp.
A7248) 		5 / 12 LEU A 119
PHE A 123
LEU A 166
SER A 145
VAL A 240
 None
 1.25A 3w1wA-3wohA:
3.7		 3w1wA-3wohA:
21.35