SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3won'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 8 GLN A  33
LEU A  34
LEU A  56
SER A 578
 None
 1.04A 1hk2A-3wonA:
undetectable		 1hk2A-3wonA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 8 LEU A 155
SER A 178
SER A 180
GLN A 558
 None
 1.09A 1ig3A-3wonA:
undetectable
1ig3B-3wonA:
undetectable		 1ig3A-3wonA:
16.02
1ig3B-3wonA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 ALA A 201
PHE A 107
GLY A 106
ALA A 226
HIS A  85
 None
 1.13A 1mjqC-3wonA:
undetectable
1mjqD-3wonA:
undetectable		 1mjqC-3wonA:
9.02
1mjqD-3wonA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 10 ALA A 226
HIS A  85
ALA A 201
PHE A 107
GLY A 106
 None
 1.13A 1mjqG-3wonA:
undetectable
1mjqH-3wonA:
undetectable		 1mjqG-3wonA:
9.02
1mjqH-3wonA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 ALA A 201
PHE A 107
GLY A 106
ALA A 226
HIS A  85
 None
 1.13A 1mjqI-3wonA:
undetectable
1mjqJ-3wonA:
undetectable		 1mjqI-3wonA:
9.02
1mjqJ-3wonA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 GLY A 274
PRO A 273
THR A  71
GLY A 655
 None
None
None
TYR  A 802 (-3.8A)
 0.82A 1usqA-3wonA:
undetectable		 1usqA-3wonA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 GLY A 274
PRO A 273
THR A  71
GLY A 655
 None
None
None
TYR  A 802 (-3.8A)
 0.83A 1usqF-3wonA:
undetectable		 1usqF-3wonA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 LEU A 622
ILE A 704
GLY A 223
ASP A 214
GLY A 210
 None
 0.98A 1zz1C-3wonA:
undetectable		 1zz1C-3wonA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		3 / 3 LYS A 609
ASP A 336
ASP A 214
 None
 0.90A 2br4D-3wonA:
undetectable		 2br4D-3wonA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 6 ARG A 278
ASP A 574
THR A 276
ASP A 651
 None
 1.17A 2j2pE-3wonA:
undetectable
2j2pF-3wonA:
undetectable		 2j2pE-3wonA:
14.86
2j2pF-3wonA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 GLY A 274
PRO A 273
THR A  71
GLY A 655
 None
None
None
TYR  A 802 (-3.8A)
 0.86A 2jklA-3wonA:
undetectable		 2jklA-3wonA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 GLY A 274
PRO A 273
THR A  71
GLY A 655
 None
None
None
TYR  A 802 (-3.8A)
 0.86A 2jklC-3wonA:
undetectable		 2jklC-3wonA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 GLY A 274
PRO A 273
THR A  71
GLY A 655
 None
None
None
TYR  A 802 (-3.8A)
 0.88A 2jklD-3wonA:
undetectable		 2jklD-3wonA:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 PHE A 227
SER A  73
LEU A  67
LEU A 701
LEU A 668
 None
 1.30A 2prgB-3wonA:
undetectable		 2prgB-3wonA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 8 ARG A 494
GLN A 526
GLN A 457
TRP A 479
 None
 1.50A 2vxaB-3wonA:
undetectable
2vxaG-3wonA:
undetectable
2vxaH-3wonA:
undetectable		 2vxaB-3wonA:
8.67
2vxaG-3wonA:
8.67
2vxaH-3wonA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 ILE A  53
LYS A  25
LEU A  34
ILE A  37
ALA A  38
 None
 1.12A 3a50A-3wonA:
2.3		 3a50A-3wonA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 10 VAL A 206
LEU A 603
VAL A 644
VAL A 606
LEU A 622
 None
 1.04A 3gwxA-3wonA:
undetectable		 3gwxA-3wonA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 SER A  73
VAL A  75
VAL A  82
LEU A 671
 None
 0.80A 3o14A-3wonA:
undetectable		 3o14A-3wonA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		3 / 3 LYS A 351
ARG A 553
LEU A 560
 None
 1.36A 3v4tE-3wonA:
undetectable		 3v4tE-3wonA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 6 THR A 331
ASN A 334
GLY A 337
ASP A 336
 None
 1.34A 3w9tE-3wonA:
undetectable		 3w9tE-3wonA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 8 ARG A 220
VAL A 696
THR A 222
GLY A 207
 VAL  A 801 (-4.5A)
None
None
None
 0.63A 4eq4B-3wonA:
undetectable		 4eq4B-3wonA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		3 / 3 LYS A 387
ARG A 390
TRP A 291
 None
 1.27A 4i90A-3wonA:
undetectable		 4i90A-3wonA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 LEU A 127
ALA A  66
THR A  71
SER A 659
 None
GOL  A 805 ( 4.4A)
None
None
 1.04A 4iklA-3wonA:
undetectable
4iklB-3wonA:
undetectable		 4iklA-3wonA:
11.42
4iklB-3wonA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 SER A  73
LEU A  67
VAL A 196
LEU A 701
LEU A 668
 None
 1.31A 4o8fB-3wonA:
undetectable		 4o8fB-3wonA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 6 PRO A 273
ILE A 581
VAL A 661
THR A  71
 None
 1.18A 4xe5A-3wonA:
undetectable		 4xe5A-3wonA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		3 / 3 ASN A 576
SER A 578
ARG A 186
 None
 0.89A 5b2qA-3wonA:
undetectable		 5b2qA-3wonA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 MET A 705
ILE A 704
LEU A 714
GLY A 204
PHE A 225
 None
 1.17A 5byjA-3wonA:
undetectable		 5byjA-3wonA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		6 / 12 GLY A 106
GLY A 223
GLY A 207
THR A 222
HIS A  86
VAL A 696
 None
None
None
None
VAL  A 801 (-3.6A)
None
 1.40A 5kqrA-3wonA:
undetectable		 5kqrA-3wonA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		6 / 12 GLY A 106
GLY A 223
GLY A 207
THR A 222
HIS A  86
VAL A 696
 None
None
None
None
VAL  A 801 (-3.6A)
None
 1.41A 5m5bA-3wonA:
undetectable		 5m5bA-3wonA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		6 / 12 GLY A 106
GLY A 223
GLY A 207
THR A 222
HIS A  86
VAL A 696
 None
None
None
None
VAL  A 801 (-3.6A)
None
 1.38A 5njvB-3wonA:
undetectable		 5njvB-3wonA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 10 MET A 705
ILE A 704
LEU A 714
LEU A 198
PHE A 225
 None
 1.24A 5tixB-3wonA:
undetectable		 5tixB-3wonA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 PHE A 227
SER A  73
LEU A  67
LEU A 701
LEU A 668
 None
 1.29A 5y2oA-3wonA:
undetectable		 5y2oA-3wonA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		5 / 12 PHE A 227
SER A  73
LEU A  67
LEU A 701
LEU A 668
 None
 1.28A 5ycpA-3wonA:
undetectable		 5ycpA-3wonA:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 LEU A 162
ASP A 136
THR A 134
TYR A 185
 None
 1.26A 5z85C-3wonA:
1.2
5z85N-3wonA:
undetectable
5z85P-3wonA:
3.4		 5z85C-3wonA:
15.49
5z85N-3wonA:
20.72
5z85P-3wonA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 4 PHE A 256
ASP A 258
LEU A 668
LYS A 667
 None
 1.30A 6awvA-3wonA:
undetectable		 6awvA-3wonA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3won DIPEPTIDYL
AMINOPEPTIDASE BII
(Pseudoxanthomona
s
mexicana) 		4 / 7 ILE A 345
GLN A 350
ALA A 289
THR A 288
 None
 0.91A 6cduC-3wonA:
3.6
6cduD-3wonA:
3.4		 6cduC-3wonA:
17.68
6cduD-3wonA:
17.68