SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wov'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 7 SER A 693
PHE A 682
ALA A 699
PHE A 695
 None
 1.12A 1fxvA-3wovA:
undetectable
1fxvB-3wovA:
undetectable		 1fxvA-3wovA:
19.60
1fxvB-3wovA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 6 SER A 506
TYR A 508
VAL A 829
ASP A 862
 None
 1.31A 2x45A-3wovA:
undetectable		 2x45A-3wovA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		5 / 12 ASP A 771
LEU A 821
ILE A 765
PHE A 732
ASP A 559
 None
 0.98A 3ko0G-3wovA:
undetectable
3ko0H-3wovA:
undetectable
3ko0I-3wovA:
undetectable
3ko0J-3wovA:
undetectable		 3ko0G-3wovA:
9.96
3ko0H-3wovA:
9.96
3ko0I-3wovA:
9.96
3ko0J-3wovA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		3 / 3 ARG A 590
LYS A 890
ARG A 591
 None
 1.02A 3w1wA-3wovA:
undetectable
3w1wB-3wovA:
undetectable		 3w1wA-3wovA:
21.75
3w1wB-3wovA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 5 TRP A 514
GLY A 585
ALA A 550
PHE A 568
 None
 1.23A 3wqwA-3wovA:
undetectable		 3wqwA-3wovA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 5 PHE A 735
TYR A 961
THR A 776
ILE A 772
 None
 0.95A 4jx1E-3wovA:
undetectable		 4jx1E-3wovA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 4 LYS A 933
LEU A 936
GLU A 937
LEU A 944
 None
 1.42A 4k4yE-3wovA:
undetectable		 4k4yE-3wovA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		3 / 3 GLY A 757
PRO A 756
ALA A 970
 None
 0.56A 4qn9B-3wovA:
undetectable		 4qn9B-3wovA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 4 ASN A 798
ILE A 737
TYR A 738
PHE A 718
 None
 1.11A 5igvA-3wovA:
undetectable		 5igvA-3wovA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		5 / 12 ASP A 552
GLY A 553
ASN A 554
ALA A 767
ASN A 717
 None
 1.41A 5kbwA-3wovA:
undetectable		 5kbwA-3wovA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		5 / 12 ASP A 552
GLY A 553
ASN A 554
ALA A 767
ASN A 717
 None
 1.23A 5kc4E-3wovA:
undetectable		 5kc4E-3wovA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		5 / 10 THR A 605
ILE A 606
LEU A 684
ALA A 550
PHE A 695
 None
 1.17A 5mxbA-3wovA:
undetectable		 5mxbA-3wovA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OAJ_E_TKTE601_1
()		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 8 GLU A 958
PHE A 735
TYR A 961
ARG A 770
 None
 1.46A 5oajD-3wovA:
undetectable
5oajE-3wovA:
undetectable		 5oajD-3wovA:
17.90
5oajE-3wovA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3wov OLIGOSACCHARYL
TRANSFERASE
(Pyrococcus
abyssi) 		4 / 7 ILE A 696
VAL A 690
ILE A 606
THR A 604
 None
 0.98A 6cduF-3wovA:
undetectable
6cduG-3wovA:
undetectable		 6cduF-3wovA:
21.63
6cduG-3wovA:
21.63