SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3woy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		4 / 5 LEU A  88
ALA A 122
ILE A  80
SER A 118
 None
 1.11A 2othA-3woyA:
undetectable		 2othA-3woyA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		5 / 12 THR A 159
ALA A 200
PHE A 171
ALA A 175
GLY A 139
 None
 1.27A 2ve3B-3woyA:
undetectable		 2ve3B-3woyA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		4 / 8 VAL A  77
LEU A  88
GLY A 123
ALA A 124
 None
 0.94A 2xfsA-3woyA:
undetectable		 2xfsA-3woyA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		4 / 8 VAL A  77
LEU A  88
GLY A 123
ALA A 124
 None
 0.95A 2xh9A-3woyA:
undetectable		 2xh9A-3woyA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_1
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		5 / 12 LEU A  99
LEU A 113
ALA A 156
VAL A 160
LEU A 216
 None
 1.16A 3b0wA-3woyA:
undetectable		 3b0wA-3woyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		3 / 3 THR A 181
THR A 159
LEU A  99
 None
 0.69A 5m66D-3woyA:
undetectable		 5m66D-3woyA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		4 / 5 ARG A 154
THR A 195
ALA A 199
ASP A  66
 None
 1.31A 5mfxA-3woyA:
undetectable		 5mfxA-3woyA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3woy CLIP-ASSOCIATING
PROTEIN 2
(Homo
sapiens) 		4 / 5 ILE A 178
THR A 181
THR A 159
LEU A  99
 None
 0.88A 6f3mD-3woyA:
undetectable		 6f3mD-3woyA:
19.03