SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wp5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		4 / 8 ALA A  33
ASN A  38
GLY A 204
GLY A 209
 None
 0.84A 1rukH-3wp5A:
undetectable
1rukL-3wp5A:
undetectable		 1rukH-3wp5A:
22.05
1rukL-3wp5A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		3 / 3 ASP A 114
PHE A  82
ARG A 170
 None
 0.74A 2a3aA-3wp5A:
undetectable		 2a3aA-3wp5A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_A_FLPA1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 1.08A 2aylA-3wp5A:
undetectable		 2aylA-3wp5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 1.06A 2aylB-3wp5A:
undetectable		 2aylB-3wp5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 MET A  78
PHE A  66
ALA A 197
ILE A 153
THR A 103
 None
 1.34A 2bjfA-3wp5A:
undetectable		 2bjfA-3wp5A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		3 / 3 TYR A  58
GLY A  36
PHE A  52
 None
 0.70A 2m2pB-3wp5A:
undetectable		 2m2pB-3wp5A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 TYR A 141
GLY A  98
ASP A 215
VAL A  85
ARG A 166
 None
 1.32A 3dlcA-3wp5A:
undetectable		 3dlcA-3wp5A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 GLY A 173
GLY A  98
PHE A 216
ALA A 214
ASP A 215
 None
 1.15A 3keeA-3wp5A:
undetectable		 3keeA-3wp5A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 1.02A 3n8xB-3wp5A:
undetectable		 3n8xB-3wp5A:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		4 / 8 GLY A 173
THR A 174
ARG A 166
GLN A   1
 None
 0.92A 3rglA-3wp5A:
undetectable		 3rglA-3wp5A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		4 / 5 GLU A 185
GLY A 188
TYR A 162
GLU A 145
 None
 1.07A 3w9tC-3wp5A:
undetectable		 3w9tC-3wp5A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 GLY A  46
ALA A 219
PHE A  42
ILE A  24
VAL A  27
 None
 1.26A 4azsA-3wp5A:
undetectable		 4azsA-3wp5A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 GLY A  46
ALA A 219
PHE A  42
ILE A  24
VAL A  27
 None
 1.27A 4azwA-3wp5A:
undetectable		 4azwA-3wp5A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		3 / 3 TYR A 141
PHE A  82
ARG A 166
 None
 1.14A 4g19D-3wp5A:
undetectable		 4g19D-3wp5A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOS_A_4KOA201_1
(UNCHARACTERIZED
PROTEIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 ARG A  61
TYR A 100
GLY A 101
PHE A 159
ARG A 148
 None
 1.40A 4kosA-3wp5A:
undetectable		 4kosA-3wp5A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 ARG A  61
TYR A 100
GLY A 101
PHE A 159
ARG A 148
 None
 1.46A 4kovA-3wp5A:
undetectable		 4kovA-3wp5A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 ARG A  61
TYR A 100
GLY A 101
PHE A 159
ARG A 148
 None
 1.40A 4kowA-3wp5A:
undetectable		 4kowA-3wp5A:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 ASN A 207
GLY A 209
ASN A  54
ASN A  38
GLY A  36
 None
 1.10A 4n09A-3wp5A:
undetectable		 4n09A-3wp5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 1.02A 4rrwD-3wp5A:
undetectable		 4rrwD-3wp5A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 1.02A 4rrzD-3wp5A:
undetectable		 4rrzD-3wp5A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 GLU A 202
TYR A 111
TYR A  96
ASP A  57
LEU A  59
 None
 1.21A 4xqeA-3wp5A:
undetectable		 4xqeA-3wp5A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B504_1
(HOMOSPERMIDINE
SYNTHASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 GLU A 202
TYR A 111
TYR A  96
ASP A  57
LEU A  59
 None
 1.22A 4xqeB-3wp5A:
undetectable		 4xqeB-3wp5A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XRG_B_AG2B502_1
(HOMOSPERMIDINE
SYNTHASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 GLU A 202
TYR A 111
TYR A  96
ASP A  57
LEU A  59
 None
 1.22A 4xrgB-3wp5A:
undetectable		 4xrgB-3wp5A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		3 / 3 LYS A  70
ILE A  75
ILE A 223
 None
 0.61A 4y0qA-3wp5A:
undetectable		 4y0qA-3wp5A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 10 GLY A  98
LEU A 200
GLU A 196
TYR A 110
TYR A 111
 None
 1.16A 5hwkA-3wp5A:
undetectable		 5hwkA-3wp5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 10 GLY A  98
LEU A 200
GLU A 196
TYR A 110
TYR A 111
 None
 1.17A 5hwkB-3wp5A:
undetectable		 5hwkB-3wp5A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 1.00A 5ikqA-3wp5A:
undetectable		 5ikqA-3wp5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_B_JMSB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 0.98A 5ikqB-3wp5A:
undetectable		 5ikqB-3wp5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 LEU A  59
GLY A 204
ALA A 203
SER A  95
LEU A 117
 None
 0.98A 5ikrB-3wp5A:
undetectable		 5ikrB-3wp5A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		3 / 3 HIS A 195
SER A  65
ARG A  61
 None
 0.71A 5u63A-3wp5A:
undetectable		 5u63A-3wp5A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 3wp5 CDBFV
(Neocallimastix
patriciarum) 		5 / 12 VAL A 199
VAL A 221
PHE A  48
HIS A   9
ILE A  24
 None
 1.23A 6mxtA-3wp5A:
undetectable		 6mxtA-3wp5A:
18.59