SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wp8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 3wp8 TRIMERIC
AUTOTRANSPORTER
ADHESIN
(Acinetobacter
sp.
Tol
5) 		3 / 3 ASP A2954
LEU A2941
LEU A2943
 None
 0.76A 1ikeA-3wp8A:
undetectable		 1ikeA-3wp8A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3wp8 TRIMERIC
AUTOTRANSPORTER
ADHESIN
(Acinetobacter
sp.
Tol
5) 		5 / 12 ALA A3029
ILE A3042
ASN A3023
ILE A3005
ALA A3007
 None
 1.14A 2ejtA-3wp8A:
undetectable		 2ejtA-3wp8A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 3wp8 TRIMERIC
AUTOTRANSPORTER
ADHESIN
(Acinetobacter
sp.
Tol
5) 		3 / 3 SER A2888
TYR A2891
HIS A2892
 None
 0.53A 2r2vD-3wp8A:
undetectable		 2r2vD-3wp8A:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 3wp8 TRIMERIC
AUTOTRANSPORTER
ADHESIN
(Acinetobacter
sp.
Tol
5) 		5 / 9 ALA A3015
SER A3013
GLY A3024
SER A3043
ALA A3036
 None
 1.44A 2vh3A-3wp8A:
undetectable		 2vh3A-3wp8A:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 3wp8 TRIMERIC
AUTOTRANSPORTER
ADHESIN
(Acinetobacter
sp.
Tol
5) 		5 / 9 ALA A3034
ALA A3015
SER A3013
GLY A3024
SER A3043
 None
 1.24A 2vh3A-3wp8A:
undetectable		 2vh3A-3wp8A:
13.29