SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wp9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		4 / 5 LEU A  17
SER A  70
LEU A  73
GLY A  35
 None
 1.02A 1a4lC-3wp9A:
undetectable		 1a4lC-3wp9A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		3 / 3 ALA A   1
VAL A 135
TRP A 136
 None
 0.82A 1nt5A-3wp9A:
undetectable		 1nt5A-3wp9A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		3 / 3 ALA A   1
VAL A 135
TRP A 136
 None
 0.83A 1nt5B-3wp9A:
undetectable		 1nt5B-3wp9A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		4 / 4 TRP A 136
SER A  18
LYS A  19
VAL A  78
 None
 1.34A 1qu3A-3wp9A:
0.0		 1qu3A-3wp9A:
12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		3 / 3 LEU A  76
LEU A  73
SER A  70
 None
 0.64A 1tlmA-3wp9A:
undetectable		 1tlmA-3wp9A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		5 / 11 LEU A  45
ILE A  39
PRO A  38
MET A  55
LEU A 209
 None
 1.09A 2ft9A-3wp9A:
undetectable		 2ft9A-3wp9A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		4 / 8 TYR A   4
GLU A   7
VAL A 113
ARG A  91
 None
 1.23A 3b9lA-3wp9A:
undetectable		 3b9lA-3wp9A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		5 / 12 THR A 108
ILE A 104
GLY A 105
ASN A 129
PRO A 111
 None
 1.01A 3eeyD-3wp9A:
undetectable		 3eeyD-3wp9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		5 / 12 PHE A 164
LEU A 154
GLY A 199
GLY A 181
LEU A 202
 None
 1.16A 3i5uA-3wp9A:
undetectable		 3i5uA-3wp9A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		3 / 3 GLN A 210
THR A 195
ASN A 192
 None
 0.81A 3v4tE-3wp9A:
undetectable		 3v4tE-3wp9A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		5 / 12 ALA A   1
GLY A 130
THR A 108
ILE A 104
LEU A  99
 None
 1.03A 4n49A-3wp9A:
undetectable		 4n49A-3wp9A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3wp9 ICE-BINDING PROTEIN
(Colwellia
sp.
SLW05) 		4 / 6 ASP A  95
ILE A 137
ARG A  91
TYR A   4
 None
 1.25A 5igyA-3wp9A:
undetectable		 5igyA-3wp9A:
21.78