SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wpa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FP9_D_SAMD401_0 (METHYLTRANSFERASE NSUN4)	3wpa	TRIMERIC AUTOTRANSPORTER ADHESIN (Acinetobacter sp. Tol 5)	5 / 12	PRO A3502 GLY A3488 GLY A3487 ASP A3508 GLY A3507	None	0.99A	4fp9D-3wpaA: undetectable	4fp9D-3wpaA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_A_LYAA302_1 (THYMIDYLATE SYNTHASE)	3wpa	TRIMERIC AUTOTRANSPORTER ADHESIN (Acinetobacter sp. Tol 5)	5 / 12	LEU A3486 GLY A3487 TYR A3485 VAL A3482 ALA A3481	None	1.20A	4fqsA-3wpaA: undetectable	4fqsA-3wpaA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FQS_B_LYAB302_1 (THYMIDYLATE SYNTHASE)	3wpa	TRIMERIC AUTOTRANSPORTER ADHESIN (Acinetobacter sp. Tol 5)	5 / 12	LEU A3486 GLY A3487 TYR A3485 VAL A3482 ALA A3481	None	1.19A	4fqsB-3wpaA: undetectable	4fqsB-3wpaA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FZV_A_SAMA401_0 (PUTATIVE METHYLTRANSFERASE NSUN4)	3wpa	TRIMERIC AUTOTRANSPORTER ADHESIN (Acinetobacter sp. Tol 5)	5 / 12	PRO A3502 GLY A3488 GLY A3487 ASP A3508 GLY A3507	None	1.00A	4fzvA-3wpaA: undetectable	4fzvA-3wpaA: 20.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4FP9_D_SAMD401_0","METHYLTRANSFERASE NSUN4","3wpa","TRIMERIC AUTOTRANSPORTER ADHESIN","Acinetobacter sp. Tol 5",5,"PRO A3502;GLY A3488;GLY A3487;ASP A3508;GLY A3507","None","0.99A","4fp9D-3wpaA:undetectable","4fp9D-3wpaA:20.75"],["4FQS_A_LYAA302_1","THYMIDYLATE SYNTHASE","3wpa","TRIMERIC AUTOTRANSPORTER ADHESIN","Acinetobacter sp. Tol 5",5,"LEU A3486;GLY A3487;TYR A3485;VAL A3482;ALA A3481","None","1.20A","4fqsA-3wpaA:undetectable","4fqsA-3wpaA:21.62"],["4FQS_B_LYAB302_1","THYMIDYLATE SYNTHASE","3wpa","TRIMERIC AUTOTRANSPORTER ADHESIN","Acinetobacter sp. Tol 5",5,"LEU A3486;GLY A3487;TYR A3485;VAL A3482;ALA A3481","None","1.19A","4fqsB-3wpaA:undetectable","4fqsB-3wpaA:21.62"],["4FZV_A_SAMA401_0","PUTATIVE METHYLTRANSFERASE NSUN4","3wpa","TRIMERIC AUTOTRANSPORTER ADHESIN","Acinetobacter sp. Tol 5",5,"PRO A3502;GLY A3488;GLY A3487;ASP A3508;GLY A3507","None","1.00A","4fzvA-3wpaA:undetectable","4fzvA-3wpaA:20.51"]]