SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wq4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 4 VAL A 273
TRP A 471
TRP A 205
 None
 1.34A 1gmkC-3wq4A:
undetectable
1gmkD-3wq4A:
undetectable		 1gmkC-3wq4A:
2.41
1gmkD-3wq4A:
2.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 5 TYR A 345
LEU A 400
THR A 271
ARG A 111
 None
 1.37A 1i2wA-3wq4A:
undetectable		 1i2wA-3wq4A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 7 LEU A 361
ARG A 321
ASP A 366
LEU A 317
 None
 0.87A 1n13D-3wq4A:
undetectable
1n13E-3wq4A:
undetectable		 1n13D-3wq4A:
12.15
1n13E-3wq4A:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 7 PHE A 171
GLU A 165
LEU A 160
TYR A 168
 None
 1.18A 1rmtB-3wq4A:
1.6		 1rmtB-3wq4A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 5 LEU A 102
ILE A 149
LEU A 145
SER A 146
 None
 0.93A 2byoA-3wq4A:
undetectable		 2byoA-3wq4A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA803_0
(FERROCHELATASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 5 LEU A 160
PRO A 161
LEU A 164
ILE A 176
 None
 0.77A 2qd4A-3wq4A:
undetectable		 2qd4A-3wq4A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 11 ASN A 202
GLU A 203
TYR A 345
GLU A 416
TRP A 463
 None
 0.85A 2v3dB-3wq4A:
6.9		 2v3dB-3wq4A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 SER A 206
GLU A 470
ASP A 421
 None
 0.80A 2zulA-3wq4A:
undetectable		 2zulA-3wq4A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 SER A 206
GLU A 470
ASP A 421
 None
 0.81A 3dmhA-3wq4A:
undetectable		 3dmhA-3wq4A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 7 PHE A  39
PHE A  45
TYR A 460
GLY A 341
 None
 1.03A 3em0B-3wq4A:
undetectable		 3em0B-3wq4A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 6 ASN A 202
MET A 201
ILE A 199
GLU A 203
 None
 1.22A 3kp6A-3wq4A:
undetectable
3kp6B-3wq4A:
undetectable		 3kp6A-3wq4A:
14.65
3kp6B-3wq4A:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 11 LEU A 466
ALA A  47
GLY A 106
PRO A 494
VAL A 482
 None
 0.95A 3oy4A-3wq4A:
undetectable		 3oy4A-3wq4A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		6 / 12 LEU A 120
ALA A 163
ASP A 166
ILE A  67
GLY A 170
ILE A 176
 None
 1.49A 3spkB-3wq4A:
undetectable		 3spkB-3wq4A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 12 ARG A 118
GLY A  85
SER A  83
GLU A  55
ALA A  88
 None
 1.39A 3t7sC-3wq4A:
undetectable		 3t7sC-3wq4A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 PHE A 225
SER A 234
SER A 362
 None
 0.89A 3ufgB-3wq4A:
undetectable		 3ufgB-3wq4A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_1
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 TYR A 402
ASP A 295
ASP A 288
 None
 0.77A 4a6eA-3wq4A:
undetectable		 4a6eA-3wq4A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_A_PXLA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 7 GLY A  56
ASP A  86
GLY A  85
HIS A  73
 None
 0.77A 4c5nA-3wq4A:
undetectable		 4c5nA-3wq4A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 8 GLY A  56
ASP A  86
GLY A  85
HIS A  73
 None
 0.76A 4c5nC-3wq4A:
undetectable		 4c5nC-3wq4A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 11 LEU A 466
ALA A  47
GLY A 106
PRO A 494
VAL A 482
 None
 0.96A 4dqeA-3wq4A:
undetectable		 4dqeA-3wq4A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 4 LEU A 160
PRO A 161
LEU A 164
ILE A 176
 None
 0.84A 4f4dB-3wq4A:
undetectable		 4f4dB-3wq4A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 ASP A 159
TRP A 463
SER A 113
 None
 0.99A 4lrhB-3wq4A:
undetectable		 4lrhB-3wq4A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 ASP A 159
TRP A 463
SER A 113
 None
 1.06A 4lrhF-3wq4A:
undetectable		 4lrhF-3wq4A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 12 ILE A 149
GLY A  46
PRO A 494
VAL A 482
ILE A 481
 None
 0.91A 4q5mA-3wq4A:
undetectable		 4q5mA-3wq4A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 12 PHE A 461
ALA A 464
ILE A 414
ASN A 417
TYR A 413
 None
 1.13A 4rtpA-3wq4A:
undetectable		 4rtpA-3wq4A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 4 TYR A 460
THR A 462
GLY A  46
LEU A 505
 None
 1.41A 4w5nA-3wq4A:
2.3		 4w5nA-3wq4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 6 ILE A 302
VAL A 333
PHE A 337
THR A 200
 None
 1.18A 4xe5A-3wq4A:
undetectable		 4xe5A-3wq4A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 12 TYR A  95
TYR A  52
ASP A  90
ALA A  88
TYR A 475
 None
 1.36A 4ymgB-3wq4A:
undetectable		 4ymgB-3wq4A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 8 HIS A 443
ASN A 417
ARG A 436
THR A 384
 None
 1.26A 5db5A-3wq4A:
undetectable
5db5B-3wq4A:
undetectable		 5db5A-3wq4A:
21.80
5db5B-3wq4A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 12 ILE A 412
VAL A 411
GLY A 459
ARG A 111
VAL A 195
 None
 1.14A 5ergB-3wq4A:
undetectable		 5ergB-3wq4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 8 ASN A 417
TRP A 500
PHE A 501
THR A 384
 None
 1.40A 5hqaA-3wq4A:
6.6		 5hqaA-3wq4A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		4 / 6 ASP A 108
LEU A 107
GLY A 109
PHE A 110
 None
 1.06A 5nooC-3wq4A:
undetectable		 5nooC-3wq4A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 GLU A 405
ASP A 409
PRO A 410
 None
 0.78A 6berA-3wq4A:
undetectable		 6berA-3wq4A:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 12 PHE A 439
GLY A 418
VAL A 273
PHE A 390
ALA A 388
 None
 1.22A 6c2mB-3wq4A:
undetectable		 6c2mB-3wq4A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		3 / 3 GLN A 371
TYR A 275
ASN A 348
 None
 0.87A 6dwdC-3wq4A:
undetectable		 6dwdC-3wq4A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GS4_A_F9EA601_0
(DIPEPTIDE AND
TRIPEPTIDE PERMEASE
A)		 3wq4 BETA-PRIMEVEROSIDASE
(Camellia
sinensis) 		5 / 10 TYR A 345
SER A 206
PHE A  54
ASN A 202
GLU A 416
 None
 1.31A 6gs4A-3wq4A:
0.0		 6gs4A-3wq4A:
24.01