SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_B_2FAB500_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.31A	2zj0B-3wqbB: undetectable	2zj0B-3wqbB: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_C_2FAC500_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.31A	2zj0C-3wqbB: undetectable	2zj0C-3wqbB: 16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_A_ADNA438_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.32A	3g1uA-3wqbB: undetectable	3g1uA-3wqbB: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_B_ADNB438_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.33A	3g1uB-3wqbB: undetectable	3g1uB-3wqbB: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G1U_D_ADND438_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.29A	3g1uD-3wqbB: undetectable	3g1uD-3wqbB: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_A_RABA602_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.31A	3glqA-3wqbB: undetectable	3glqA-3wqbB: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GLQ_B_RABB602_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.33A	3glqB-3wqbB: undetectable	3glqB-3wqbB: 19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_B_SAMB301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	GLY B 64 SER B 63 ASP B 103 ILE B 107 LEU B 66	None	1.29A	3iv6B-3wqbB: undetectable	3iv6B-3wqbB: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K9W_A_ACTA170_0 (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	3 / 3	SER B 63 GLY B 64 THR B 65	None	0.20A	3k9wA-3wqbB: undetectable	3k9wA-3wqbB: 25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_A_ADNA500_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.31A	3n58A-3wqbB: undetectable	3n58A-3wqbB: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_C_ADNC500_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.34A	3n58C-3wqbB: undetectable	3n58C-3wqbB: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PFJ_B_ADNB502_1 (ADENOSYLHOMOCYSTEINA SE)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.30A	4pfjB-3wqbB: undetectable	4pfjB-3wqbB: 16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA502_1 (CYTOCHROME P450 2C9)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	4 / 6	PRO B 100 GLY B 101 THR B 102 LYS B 44	None	1.05A	5xxiA-3wqbB: undetectable	5xxiA-3wqbB: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_A_ADNA505_1 (-)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.32A	6f3nA-3wqbB: undetectable	6f3nA-3wqbB: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_C_ADNC505_1 (-)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.26A	6f3nC-3wqbB: undetectable	6f3nC-3wqbB: 15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_D_ADND506_1 (-)	3wqb	OPEN READING FRAME 2 (Aeromonas sobria)	5 / 12	THR B 102 LEU B 96 LEU B 84 GLY B 83 HIS B 82	None	1.32A	6f3nD-3wqbB: undetectable	6f3nD-3wqbB: 15.38

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZJ0_B_2FAB500_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.31A","2zj0B-3wqbB:undetectable","2zj0B-3wqbB:16.81"],["2ZJ0_C_2FAC500_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.31A","2zj0C-3wqbB:undetectable","2zj0C-3wqbB:16.81"],["3G1U_A_ADNA438_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.32A","3g1uA-3wqbB:undetectable","3g1uA-3wqbB:15.83"],["3G1U_B_ADNB438_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.33A","3g1uB-3wqbB:undetectable","3g1uB-3wqbB:15.83"],["3G1U_D_ADND438_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.29A","3g1uD-3wqbB:undetectable","3g1uD-3wqbB:15.83"],["3GLQ_A_RABA602_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.31A","3glqA-3wqbB:undetectable","3glqA-3wqbB:19.33"],["3GLQ_B_RABB602_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.33A","3glqB-3wqbB:undetectable","3glqB-3wqbB:19.33"],["3IV6_B_SAMB301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"GLY B  64;SER B  63;ASP B 103;ILE B 107;LEU B  66","None","1.29A","3iv6B-3wqbB:undetectable","3iv6B-3wqbB:20.53"],["3K9W_A_ACTA170_0","PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",3,"SER B  63;GLY B  64;THR B  65","None","0.20A","3k9wA-3wqbB:undetectable","3k9wA-3wqbB:25.81"],["3N58_A_ADNA500_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.31A","3n58A-3wqbB:undetectable","3n58A-3wqbB:16.16"],["3N58_C_ADNC500_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.34A","3n58C-3wqbB:undetectable","3n58C-3wqbB:16.16"],["4PFJ_B_ADNB502_1","ADENOSYLHOMOCYSTEINASE","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.30A","4pfjB-3wqbB:undetectable","4pfjB-3wqbB:16.37"],["5XXI_A_LSNA502_1","CYTOCHROME P450 2C9","3wqb","OPEN READING FRAME 2","Aeromonas sobria",4,"PRO B 100;GLY B 101;THR B 102;LYS B  44","None","1.05A","5xxiA-3wqbB:undetectable","5xxiA-3wqbB:15.66"],["6F3N_A_ADNA505_1","-","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.32A","6f3nA-3wqbB:undetectable","6f3nA-3wqbB:15.38"],["6F3N_C_ADNC505_1","-","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.26A","6f3nC-3wqbB:undetectable","6f3nC-3wqbB:15.38"],["6F3N_D_ADND506_1","-","3wqb","OPEN READING FRAME 2","Aeromonas sobria",5,"THR B 102;LEU B  96;LEU B  84;GLY B  83;HIS B  82","None","1.32A","6f3nD-3wqbB:undetectable","6f3nD-3wqbB:15.38"]]