SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wrc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 7 TYR A  54
GLY A 125
ILE A  16
GLY A 188
 None
 0.82A 11gsB-3wrcA:
undetectable		 11gsB-3wrcA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 10 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 0.87A 1hsgA-3wrcA:
undetectable		 1hsgA-3wrcA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 7 ARG A 143
ALA A 185
GLY A   6
ILE A   4
 None
 0.93A 2fxdB-3wrcA:
undetectable		 2fxdB-3wrcA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 9 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 1.03A 2o4pB-3wrcA:
undetectable		 2o4pB-3wrcA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A 130
PRO A 129
LEU A 133
 None
 0.56A 2po7B-3wrcA:
2.4		 2po7B-3wrcA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 12 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 0.99A 2qakB-3wrcA:
undetectable		 2qakB-3wrcA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A 134
PRO A 135
ARG A 143
 None
 0.64A 2qd5A-3wrcA:
undetectable		 2qd5A-3wrcA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_2
(AAC(6')-IB)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		3 / 3 TRP A  43
GLN A 277
TRP A 243
 None
 1.33A 2vqyA-3wrcA:
undetectable		 2vqyA-3wrcA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 4 ILE A   4
GLN A  47
ILE A 180
LEU A 273
 None
 1.33A 3dzyD-3wrcA:
undetectable		 3dzyD-3wrcA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 10 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 0.94A 3em3A-3wrcA:
undetectable		 3em3A-3wrcA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 8 TYR A  54
GLY A 125
ILE A  16
GLY A 188
 None
 0.81A 3n9jB-3wrcA:
undetectable		 3n9jB-3wrcA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 9 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 0.97A 3oxvA-3wrcA:
undetectable		 3oxvA-3wrcA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 10 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 1.03A 3oxwD-3wrcA:
undetectable		 3oxwD-3wrcA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 9 ARG A 143
ALA A 185
GLY A   6
ILE A   4
PRO A  49
 None
 1.32A 3spkA-3wrcA:
undetectable		 3spkA-3wrcA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.11A 3wg7A-3wrcA:
undetectable
3wg7B-3wrcA:
undetectable
3wg7T-3wrcA:
undetectable		 3wg7A-3wrcA:
22.00
3wg7B-3wrcA:
17.69
3wg7T-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.09A 3x2qA-3wrcA:
undetectable
3x2qB-3wrcA:
undetectable
3x2qT-3wrcA:
undetectable		 3x2qA-3wrcA:
22.00
3x2qB-3wrcA:
17.69
3x2qT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 LEU A  99
LEU A 147
ILE A 184
ILE A 103
PHE A  70
 None
 1.48A 4a7aA-3wrcA:
undetectable		 4a7aA-3wrcA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 10 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 0.90A 4dqfB-3wrcA:
undetectable		 4dqfB-3wrcA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 5 GLY A 234
GLY A 233
ASN A 203
GLU A 236
 None
 1.13A 4fglC-3wrcA:
undetectable		 4fglC-3wrcA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 10 ILE A 173
ALA A 249
LEU A 245
PHE A  53
ILE A 103
 None
 1.04A 4g8zX-3wrcA:
undetectable		 4g8zX-3wrcA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		3 / 3 LEU A 134
PRO A 135
ARG A 143
 None
 0.69A 4klrB-3wrcA:
undetectable		 4klrB-3wrcA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 12 LEU A 107
ALA A 249
ILE A 173
ALA A 172
ILE A 184
 None
 0.98A 4o2bD-3wrcA:
undetectable		 4o2bD-3wrcA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		3 / 3 PRO A 129
LEU A 133
HIS A 258
 None
 0.69A 4pevA-3wrcA:
undetectable		 4pevA-3wrcA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 LEU A  99
ALA A 172
GLY A 166
VAL A 145
ILE A 103
 None
 0.89A 4qgiB-3wrcA:
undetectable		 4qgiB-3wrcA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_1
(BETA-LACTOGLOBULIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		3 / 3 LYS A   2
ILE A   4
ILE A 184
 None
 0.60A 4y0qA-3wrcA:
undetectable		 4y0qA-3wrcA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.11A 5b1aA-3wrcA:
undetectable
5b1aB-3wrcA:
undetectable
5b1aT-3wrcA:
undetectable		 5b1aA-3wrcA:
22.00
5b1aB-3wrcA:
17.69
5b1aT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.14A 5b1bA-3wrcA:
0.0
5b1bB-3wrcA:
undetectable
5b1bT-3wrcA:
undetectable		 5b1bA-3wrcA:
22.00
5b1bB-3wrcA:
17.69
5b1bT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.13A 5b3sA-3wrcA:
0.0
5b3sB-3wrcA:
undetectable
5b3sT-3wrcA:
undetectable		 5b3sA-3wrcA:
22.00
5b3sB-3wrcA:
17.69
5b3sT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 7 ILE A   5
GLY A   6
LEU A  72
CYH A 142
 None
 0.89A 5hieB-3wrcA:
undetectable		 5hieB-3wrcA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 12 LEU A 122
SER A 128
SER A 131
LEU A 130
LEU A  90
 None
 1.18A 5mwyA-3wrcA:
undetectable		 5mwyA-3wrcA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 7 GLN A 193
GLY A 237
TYR A  67
ASP A 228
 None
 1.14A 5vlmE-3wrcA:
undetectable		 5vlmE-3wrcA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.13A 5x19A-3wrcA:
0.0
5x19B-3wrcA:
undetectable
5x19T-3wrcA:
undetectable		 5x19A-3wrcA:
22.00
5x19B-3wrcA:
17.69
5x19T-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.04A 5xdqA-3wrcA:
undetectable
5xdqB-3wrcA:
undetectable
5xdqT-3wrcA:
undetectable		 5xdqA-3wrcA:
22.00
5xdqB-3wrcA:
17.69
5xdqT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.10A 5xdxA-3wrcA:
0.0
5xdxB-3wrcA:
undetectable
5xdxT-3wrcA:
undetectable		 5xdxA-3wrcA:
22.00
5xdxB-3wrcA:
17.69
5xdxT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 12 LEU A 107
ALA A 249
ILE A 173
ALA A 172
ILE A 184
 None
 0.94A 5xiwD-3wrcA:
undetectable		 5xiwD-3wrcA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.09A 5z84A-3wrcA:
undetectable
5z84B-3wrcA:
undetectable
5z84T-3wrcA:
undetectable		 5z84A-3wrcA:
22.00
5z84B-3wrcA:
17.69
5z84T-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.08A 5z86A-3wrcA:
undetectable
5z86B-3wrcA:
undetectable
5z86T-3wrcA:
undetectable		 5z86A-3wrcA:
22.00
5z86B-3wrcA:
17.69
5z86T-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.09A 5zcoA-3wrcA:
undetectable
5zcoB-3wrcA:
undetectable
5zcoT-3wrcA:
undetectable		 5zcoA-3wrcA:
22.00
5zcoB-3wrcA:
17.69
5zcoT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.09A 5zcpA-3wrcA:
undetectable
5zcpB-3wrcA:
undetectable
5zcpT-3wrcA:
undetectable		 5zcpA-3wrcA:
22.00
5zcpB-3wrcA:
17.69
5zcpT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.10A 5zcqA-3wrcA:
undetectable
5zcqB-3wrcA:
undetectable
5zcqT-3wrcA:
undetectable		 5zcqA-3wrcA:
22.00
5zcqB-3wrcA:
17.69
5zcqT-3wrcA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 12 ASP A 276
LEU A 134
ALA A 185
LEU A 133
LEU A 273
 None
 1.23A 6ew0F-3wrcA:
undetectable		 6ew0F-3wrcA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		4 / 6 LEU A  99
LEU A 169
THR A  52
ARG A 247
 None
 0.85A 6ew0G-3wrcA:
undetectable		 6ew0G-3wrcA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3wrc GALLATE DIOXYGENASE
(Sphingomonas
paucimobilis) 		5 / 11 GLN A 277
ARG A 167
ARG A 247
PHE A 274
GLY A   7
 None
 1.00A 6nknA-3wrcA:
undetectable
6nknB-3wrcA:
undetectable
6nknT-3wrcA:
undetectable		 6nknA-3wrcA:
22.00
6nknB-3wrcA:
17.69
6nknT-3wrcA:
10.79