SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wrf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_A_CHDA1502_0 (FERROCHELATASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	PRO A 468 VAL A 602 GLY A 601 TRP A 469	None	0.84A	1hrkA-3wrfA: undetectable	1hrkA-3wrfA: 19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_B_CHDB2502_0 (FERROCHELATASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	PRO A 468 VAL A 602 GLY A 601 TRP A 469	None	0.85A	1hrkB-3wrfA: undetectable	1hrkB-3wrfA: 19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_A_DVAA6_0 (MINI-GRAMICIDIN A)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	ALA A 593 VAL A 602 TRP A 469	None	0.82A	1kqeA-3wrfA: undetectable 1kqeE-3wrfA: undetectable	1kqeA-3wrfA: 1.90 1kqeE-3wrfA: 1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_B_DVAB6_0 (MINI-GRAMICIDIN A)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	ALA A 593 VAL A 602 TRP A 469	None	0.83A	1kqeB-3wrfA: undetectable 1kqeD-3wrfA: undetectable	1kqeB-3wrfA: 1.90 1kqeD-3wrfA: 1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_D_DVAD6_0 (MINI-GRAMICIDIN A)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	TRP A 469 ALA A 593 VAL A 602	None	0.83A	1kqeB-3wrfA: undetectable 1kqeD-3wrfA: undetectable	1kqeB-3wrfA: 1.90 1kqeD-3wrfA: 1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KQE_E_DVAE6_0 (MINI-GRAMICIDIN A)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	TRP A 469 ALA A 593 VAL A 602	None	0.84A	1kqeA-3wrfA: undetectable 1kqeE-3wrfA: undetectable	1kqeA-3wrfA: 1.90 1kqeE-3wrfA: 1.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NX9_A_AICA5001_1 (ALPHA-AMINO ACID ESTER HYDROLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	TYR A 145 GLU A 83 SER A 428 TYR A 432	None	1.09A	1nx9A-3wrfA: undetectable	1nx9A-3wrfA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NX9_B_AICB5002_1 (ALPHA-AMINO ACID ESTER HYDROLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	TYR A 145 GLU A 83 SER A 428 TYR A 432	None	1.07A	1nx9B-3wrfA: undetectable	1nx9B-3wrfA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NX9_C_AICC5003_1 (ALPHA-AMINO ACID ESTER HYDROLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	TYR A 145 GLU A 83 SER A 428 TYR A 432	None	1.10A	1nx9C-3wrfA: undetectable	1nx9C-3wrfA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NX9_D_AICD5004_1 (ALPHA-AMINO ACID ESTER HYDROLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	TYR A 145 GLU A 83 SER A 428 TYR A 432	None	1.11A	1nx9D-3wrfA: undetectable	1nx9D-3wrfA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_B_FUAB703_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	VAL A 54 ALA A 55 HIS A 69	None	0.73A	1q23C-3wrfA: undetectable	1q23C-3wrfA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_G_FUAG708_2 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	VAL A 54 ALA A 55 HIS A 69	None	0.71A	1q23H-3wrfA: undetectable	1q23H-3wrfA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_I_FUAI707_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	VAL A 54 ALA A 55 HIS A 69	None	0.59A	1q23G-3wrfA: undetectable	1q23G-3wrfA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_L_FUAL710_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	VAL A 54 ALA A 55 HIS A 69	None	0.64A	1q23J-3wrfA: undetectable	1q23J-3wrfA: 15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1U70_A_MTXA187_1 (DIHYDROFOLATE REDUCTASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	ARG A 647 GLN A 656 ASN A 572 LEU A 576 TYR A 385	None	1.42A	1u70A-3wrfA: undetectable	1u70A-3wrfA: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OPX_A_DXCA1002_0 (ALDEHYDE DEHYDROGENASE A)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	GLY A 193 ARG A 273 TYR A 231	None	0.78A	2opxA-3wrfA: undetectable	2opxA-3wrfA: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	PRO A 468 VAL A 602 GLY A 601 TRP A 469	None	0.84A	2qd3A-3wrfA: undetectable	2qd3A-3wrfA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	SER A 7 VAL A 602 GLY A 601 TRP A 469	None	1.04A	2qd3A-3wrfA: undetectable	2qd3A-3wrfA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEB_A_HSMA145_1 (D7R4 PROTEIN)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 7	ILE A 494 ARG A 493 PHE A 467 GLU A 366	None	1.09A	2qebA-3wrfA: undetectable	2qebA-3wrfA: 12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEB_B_HSMB145_1 (D7R4 PROTEIN)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 7	ILE A 494 ARG A 493 PHE A 467 GLU A 366	None	1.13A	2qebB-3wrfA: undetectable	2qebB-3wrfA: 12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2I_B_QPSB1050_2 (ALPHA-1,4-GLUCAN LYASE ISOZYME 1)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 6	PHE A 490 TYR A 475 ARG A 493 THR A 435	None	1.47A	2x2iB-3wrfA: 5.1	2x2iB-3wrfA: 20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWC_A_SAMA501_1 (SPERMIDINE SYNTHASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 4	LEU A 598 GLN A 595 ASP A 571 ASP A 606	None	1.35A	3bwcA-3wrfA: 0.0	3bwcA-3wrfA: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CS9_C_NILC600_2 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 9	LEU A 330 VAL A 549 VAL A 543 VAL A 558 PHE A 655	None	1.19A	3cs9C-3wrfA: undetectable	3cs9C-3wrfA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_A_H3PA552_1 (GLUTAMATE DEHYDROGENASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 6	ILE A 197 TYR A 219 ILE A 138 HIS A 142	None	0.94A	3eteA-3wrfA: undetectable 3eteE-3wrfA: undetectable	3eteA-3wrfA: 22.92 3eteE-3wrfA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC554_1 (GLUTAMATE DEHYDROGENASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 5	ILE A 197 TYR A 219 ILE A 138 HIS A 142	None	0.95A	3eteB-3wrfA: undetectable 3eteC-3wrfA: undetectable	3eteB-3wrfA: 22.92 3eteC-3wrfA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_F_H3PF552_1 (GLUTAMATE DEHYDROGENASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 7	ILE A 138 HIS A 142 ILE A 197 TYR A 219	None	0.94A	3eteD-3wrfA: undetectable 3eteF-3wrfA: undetectable	3eteD-3wrfA: 22.92 3eteF-3wrfA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QEL_D_QELD2_1 (NMDA GLUTAMATE RECEPTOR SUBUNIT GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 5	THR A 253 PHE A 255 ARG A 224 LEU A 277	None	1.42A	3qelC-3wrfA: undetectable	3qelC-3wrfA: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S3G_A_TLTA317_1 (ALDOSE REDUCTASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 7	TYR A 276 HIS A 149 PHE A 73 CYH A 418	None	1.32A	3s3gA-3wrfA: undetectable	3s3gA-3wrfA: 17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TZF_B_08DB280_1 (7,8-DIHYDROPTEROATE SYNTHASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	PHE A 244 GLY A 193 PHE A 255 SER A 141	None	1.04A	3tzfB-3wrfA: undetectable	3tzfB-3wrfA: 16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AZS_A_SAMA1475_0 (METHYLTRANSFERASE WBDD)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	GLY A 275 ALA A 271 ARG A 224 GLU A 198 HIS A 194	None	1.17A	4azsA-3wrfA: undetectable	4azsA-3wrfA: 23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CEV_F_GAIF411_0 (PROTEIN (ARGINASE))	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 6	ARG A 637 GLU A 568 LEU A 599 ASP A 571	None	1.43A	4cevE-3wrfA: undetectable 4cevF-3wrfA: undetectable	4cevE-3wrfA: 20.09 4cevF-3wrfA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJE_A_C2FA300_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	MET A 1 PHE A 455 ASP A 430 LEU A 425 SER A 445	None	1.48A	4djeA-3wrfA: undetectable	4djeA-3wrfA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEV_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 7	ASP A 77 ASN A 421 GLU A 338 GLU A 196	None	1.23A	4fevB-3wrfA: undetectable	4fevB-3wrfA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FEW_B_KANB301_1 (AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERAS E APHA1-IAB)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 7	ASP A 77 ASN A 421 GLU A 338 GLU A 196	None	1.21A	4fewB-3wrfA: undetectable	4fewB-3wrfA: 17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MWX_A_ZMRA513_2 (NEURAMINIDASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	ARG A 13 TRP A 10 ILE A 374	None	1.02A	4mwxA-3wrfA: undetectable	4mwxA-3wrfA: 18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V20_A_ACTA1444_0 (CELLOBIOHYDROLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 5	GLY A 313 THR A 312 GLY A 337 GLU A 368	None	1.17A	4v20A-3wrfA: undetectable	4v20A-3wrfA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XK8_A_PQNA845_1 (PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 8	PHE A 467 SER A 465 LEU A 536 GLY A 471	None	1.02A	4xk8a-3wrfA: 0.5	4xk8a-3wrfA: 23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUE_A_SAMA303_0 (CATECHOL O-METHYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	VAL A 405 ILE A 374 ILE A 422 ASN A 421 CYH A 340	None	1.25A	4xueA-3wrfA: undetectable	4xueA-3wrfA: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XUE_A_SAMA303_0 (CATECHOL O-METHYLTRANSFERASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	VAL A 405 TYR A 386 ILE A 422 ASN A 421 CYH A 340	None	1.28A	4xueA-3wrfA: undetectable	4xueA-3wrfA: 16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZDY_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	TYR A 385 ILE A 377 GLY A 372 THR A 312 THR A 318	None	1.17A	4zdyA-3wrfA: undetectable	4zdyA-3wrfA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE2_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	TYR A 385 ILE A 377 GLY A 372 THR A 312 THR A 318	None	1.16A	4ze2A-3wrfA: undetectable	4ze2A-3wrfA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_D_SORD1343_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	4 / 5	ALA A 344 HIS A 270 ALA A 271 GLU A 338	None	1.16A	5a06C-3wrfA: undetectable 5a06D-3wrfA: undetectable	5a06C-3wrfA: 20.94 5a06D-3wrfA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESK_A_1YNA701_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	TYR A 385 ILE A 377 GLY A 372 THR A 312 THR A 318	None	1.12A	5eskA-3wrfA: 0.7	5eskA-3wrfA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESL_A_1YNA701_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	TYR A 385 ILE A 377 GLY A 372 THR A 312 THR A 318	None	1.17A	5eslA-3wrfA: undetectable	5eslA-3wrfA: 21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I1O_H_DVAH9_0 (D-VILLIN HEADPIECE SUBDOMAIN VILLIN-1)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	ALA A 53 ASN A 56 LEU A 57	None	0.44A	5i1oA-3wrfA: undetectable	5i1oA-3wrfA: 7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IWU_A_ERYA404_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	ILE A 138 TYR A 231 GLU A 196 ALA A 257 SER A 217	None	1.39A	5iwuA-3wrfA: undetectable	5iwuA-3wrfA: 18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JLC_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	5 / 12	TYR A 385 ILE A 377 GLY A 372 THR A 312 THR A 318	None	1.26A	5jlcA-3wrfA: undetectable	5jlcA-3wrfA: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z6J_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	3wrf	NON-REDUCING END BETA-L-ARABINOFURANO SIDASE (Bifidobacterium longum)	3 / 3	MET A 147 ASP A 115 ARG A 212	None	1.18A	5z6jA-3wrfA: undetectable	5z6jA-3wrfA: 14.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HRK_A_CHDA1502_0","FERROCHELATASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"PRO A 468;VAL A 602;GLY A 601;TRP A 469","None","0.84A","1hrkA-3wrfA:undetectable","1hrkA-3wrfA:19.41"],["1HRK_B_CHDB2502_0","FERROCHELATASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"PRO A 468;VAL A 602;GLY A 601;TRP A 469","None","0.85A","1hrkB-3wrfA:undetectable","1hrkB-3wrfA:19.41"],["1KQE_A_DVAA6_0","MINI-GRAMICIDIN A","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"ALA A 593;VAL A 602;TRP A 469","None","0.82A","1kqeA-3wrfA:undetectable;1kqeE-3wrfA:undetectable","1kqeA-3wrfA:1.90;1kqeE-3wrfA:1.90"],["1KQE_B_DVAB6_0","MINI-GRAMICIDIN A","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"ALA A 593;VAL A 602;TRP A 469","None","0.83A","1kqeB-3wrfA:undetectable;1kqeD-3wrfA:undetectable","1kqeB-3wrfA:1.90;1kqeD-3wrfA:1.90"],["1KQE_D_DVAD6_0","MINI-GRAMICIDIN A","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"TRP A 469;ALA A 593;VAL A 602","None","0.83A","1kqeB-3wrfA:undetectable;1kqeD-3wrfA:undetectable","1kqeB-3wrfA:1.90;1kqeD-3wrfA:1.90"],["1KQE_E_DVAE6_0","MINI-GRAMICIDIN A","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"TRP A 469;ALA A 593;VAL A 602","None","0.84A","1kqeA-3wrfA:undetectable;1kqeE-3wrfA:undetectable","1kqeA-3wrfA:1.90;1kqeE-3wrfA:1.90"],["1NX9_A_AICA5001_1","ALPHA-AMINO ACID ESTER HYDROLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"TYR A 145;GLU A  83;SER A 428;TYR A 432","None","1.09A","1nx9A-3wrfA:undetectable","1nx9A-3wrfA:22.79"],["1NX9_B_AICB5002_1","ALPHA-AMINO ACID ESTER HYDROLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"TYR A 145;GLU A  83;SER A 428;TYR A 432","None","1.07A","1nx9B-3wrfA:undetectable","1nx9B-3wrfA:22.79"],["1NX9_C_AICC5003_1","ALPHA-AMINO ACID ESTER HYDROLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"TYR A 145;GLU A  83;SER A 428;TYR A 432","None","1.10A","1nx9C-3wrfA:undetectable","1nx9C-3wrfA:22.79"],["1NX9_D_AICD5004_1","ALPHA-AMINO ACID ESTER HYDROLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"TYR A 145;GLU A  83;SER A 428;TYR A 432","None","1.11A","1nx9D-3wrfA:undetectable","1nx9D-3wrfA:22.79"],["1Q23_B_FUAB703_2","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"VAL A  54;ALA A  55;HIS A  69","None","0.73A","1q23C-3wrfA:undetectable","1q23C-3wrfA:15.67"],["1Q23_G_FUAG708_2","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"VAL A  54;ALA A  55;HIS A  69","None","0.71A","1q23H-3wrfA:undetectable","1q23H-3wrfA:15.67"],["1Q23_I_FUAI707_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"VAL A  54;ALA A  55;HIS A  69","None","0.59A","1q23G-3wrfA:undetectable","1q23G-3wrfA:15.67"],["1Q23_L_FUAL710_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"VAL A  54;ALA A  55;HIS A  69","None","0.64A","1q23J-3wrfA:undetectable","1q23J-3wrfA:15.67"],["1U70_A_MTXA187_1","DIHYDROFOLATE REDUCTASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"ARG A 647;GLN A 656;ASN A 572;LEU A 576;TYR A 385","None","1.42A","1u70A-3wrfA:undetectable","1u70A-3wrfA:14.42"],["2OPX_A_DXCA1002_0","ALDEHYDE DEHYDROGENASE A","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"GLY A 193;ARG A 273;TYR A 231","None","0.78A","2opxA-3wrfA:undetectable","2opxA-3wrfA:23.11"],["2QD3_A_CHDA502_0","FERROCHELATASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"PRO A 468;VAL A 602;GLY A 601;TRP A 469","None","0.84A","2qd3A-3wrfA:undetectable","2qd3A-3wrfA:19.57"],["2QD3_A_CHDA502_0","FERROCHELATASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"SER A   7;VAL A 602;GLY A 601;TRP A 469","None","1.04A","2qd3A-3wrfA:undetectable","2qd3A-3wrfA:19.57"],["2QEB_A_HSMA145_1","D7R4 PROTEIN","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ILE A 494;ARG A 493;PHE A 467;GLU A 366","None","1.09A","2qebA-3wrfA:undetectable","2qebA-3wrfA:12.65"],["2QEB_B_HSMB145_1","D7R4 PROTEIN","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ILE A 494;ARG A 493;PHE A 467;GLU A 366","None","1.13A","2qebB-3wrfA:undetectable","2qebB-3wrfA:12.65"],["2X2I_B_QPSB1050_2","ALPHA-1,4-GLUCAN LYASE ISOZYME 1","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"PHE A 490;TYR A 475;ARG A 493;THR A 435","None","1.47A","2x2iB-3wrfA:5.1","2x2iB-3wrfA:20.36"],["3BWC_A_SAMA501_1","SPERMIDINE SYNTHASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"LEU A 598;GLN A 595;ASP A 571;ASP A 606","None","1.35A","3bwcA-3wrfA:0.0","3bwcA-3wrfA:18.61"],["3CS9_C_NILC600_2","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"LEU A 330;VAL A 549;VAL A 543;VAL A 558;PHE A 655","None","1.19A","3cs9C-3wrfA:undetectable","3cs9C-3wrfA:18.83"],["3ETE_A_H3PA552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ILE A 197;TYR A 219;ILE A 138;HIS A 142","None","0.94A","3eteA-3wrfA:undetectable;3eteE-3wrfA:undetectable","3eteA-3wrfA:22.92;3eteE-3wrfA:22.92"],["3ETE_C_H3PC554_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ILE A 197;TYR A 219;ILE A 138;HIS A 142","None","0.95A","3eteB-3wrfA:undetectable;3eteC-3wrfA:undetectable","3eteB-3wrfA:22.92;3eteC-3wrfA:22.92"],["3ETE_F_H3PF552_1","GLUTAMATE DEHYDROGENASE;GLUTAMATE DEHYDROGENASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ILE A 138;HIS A 142;ILE A 197;TYR A 219","None","0.94A","3eteD-3wrfA:undetectable;3eteF-3wrfA:undetectable","3eteD-3wrfA:22.92;3eteF-3wrfA:22.92"],["3QEL_D_QELD2_1","NMDA GLUTAMATE RECEPTOR SUBUNIT;GLUTAMATE [NMDA] RECEPTOR SUBUNIT EPSILON-2","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"THR A 253;PHE A 255;ARG A 224;LEU A 277","None","1.42A","3qelC-3wrfA:undetectable","3qelC-3wrfA:20.21"],["3S3G_A_TLTA317_1","ALDOSE REDUCTASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"TYR A 276;HIS A 149;PHE A  73;CYH A 418","None","1.32A","3s3gA-3wrfA:undetectable","3s3gA-3wrfA:17.80"],["3TZF_B_08DB280_1","7,8-DIHYDROPTEROATE SYNTHASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"PHE A 244;GLY A 193;PHE A 255;SER A 141","None","1.04A","3tzfB-3wrfA:undetectable","3tzfB-3wrfA:16.72"],["4AZS_A_SAMA1475_0","METHYLTRANSFERASE WBDD","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"GLY A 275;ALA A 271;ARG A 224;GLU A 198;HIS A 194","None","1.17A","4azsA-3wrfA:undetectable","4azsA-3wrfA:23.32"],["4CEV_F_GAIF411_0","PROTEIN (ARGINASE)","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ARG A 637;GLU A 568;LEU A 599;ASP A 571","None","1.43A","4cevE-3wrfA:undetectable;4cevF-3wrfA:undetectable","4cevE-3wrfA:20.09;4cevF-3wrfA:20.09"],["4DJE_A_C2FA300_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"MET A   1;PHE A 455;ASP A 430;LEU A 425;SER A 445","None","1.48A","4djeA-3wrfA:undetectable","4djeA-3wrfA:18.21"],["4FEV_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ASP A  77;ASN A 421;GLU A 338;GLU A 196","None","1.23A","4fevB-3wrfA:undetectable","4fevB-3wrfA:17.68"],["4FEW_B_KANB301_1","AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE APHA1-IAB","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ASP A  77;ASN A 421;GLU A 338;GLU A 196","None","1.21A","4fewB-3wrfA:undetectable","4fewB-3wrfA:17.68"],["4MWX_A_ZMRA513_2","NEURAMINIDASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"ARG A  13;TRP A  10;ILE A 374","None","1.02A","4mwxA-3wrfA:undetectable","4mwxA-3wrfA:18.98"],["4V20_A_ACTA1444_0","CELLOBIOHYDROLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"GLY A 313;THR A 312;GLY A 337;GLU A 368","None","1.17A","4v20A-3wrfA:undetectable","4v20A-3wrfA:23.08"],["4XK8_A_PQNA845_1","PHOTOSYSTEM I P700 CHLOROPHYLL A APOPROTEIN A1","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"PHE A 467;SER A 465;LEU A 536;GLY A 471","None","1.02A","4xk8a-3wrfA:0.5","4xk8a-3wrfA:23.74"],["4XUE_A_SAMA303_0","CATECHOL O-METHYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"VAL A 405;ILE A 374;ILE A 422;ASN A 421;CYH A 340","None","1.25A","4xueA-3wrfA:undetectable","4xueA-3wrfA:16.89"],["4XUE_A_SAMA303_0","CATECHOL O-METHYLTRANSFERASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"VAL A 405;TYR A 386;ILE A 422;ASN A 421;CYH A 340","None","1.28A","4xueA-3wrfA:undetectable","4xueA-3wrfA:16.89"],["4ZDY_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"TYR A 385;ILE A 377;GLY A 372;THR A 312;THR A 318","None","1.17A","4zdyA-3wrfA:undetectable","4zdyA-3wrfA:21.82"],["4ZE2_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"TYR A 385;ILE A 377;GLY A 372;THR A 312;THR A 318","None","1.16A","4ze2A-3wrfA:undetectable","4ze2A-3wrfA:21.82"],["5A06_D_SORD1343_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",4,"ALA A 344;HIS A 270;ALA A 271;GLU A 338","None","1.16A","5a06C-3wrfA:undetectable;5a06D-3wrfA:undetectable","5a06C-3wrfA:20.94;5a06D-3wrfA:20.94"],["5ESK_A_1YNA701_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"TYR A 385;ILE A 377;GLY A 372;THR A 312;THR A 318","None","1.12A","5eskA-3wrfA:0.7","5eskA-3wrfA:21.82"],["5ESL_A_1YNA701_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"TYR A 385;ILE A 377;GLY A 372;THR A 312;THR A 318","None","1.17A","5eslA-3wrfA:undetectable","5eslA-3wrfA:21.82"],["5I1O_H_DVAH9_0","D-VILLIN HEADPIECE SUBDOMAIN;VILLIN-1","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"ALA A  53;ASN A  56;LEU A  57","None","0.44A","5i1oA-3wrfA:undetectable","5i1oA-3wrfA:7.03"],["5IWU_A_ERYA404_0","MACROLIDE 2'-PHOSPHOTRANSFERASE II","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"ILE A 138;TYR A 231;GLU A 196;ALA A 257;SER A 217","None","1.39A","5iwuA-3wrfA:undetectable","5iwuA-3wrfA:18.70"],["5JLC_A_1YNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",5,"TYR A 385;ILE A 377;GLY A 372;THR A 312;THR A 318","None","1.26A","5jlcA-3wrfA:undetectable","5jlcA-3wrfA:22.40"],["5Z6J_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","3wrf","NON-REDUCING END BETA-L-ARABINOFURANOSIDASE","Bifidobacterium longum",3,"MET A 147;ASP A 115;ARG A 212","None","1.18A","5z6jA-3wrfA:undetectable","5z6jA-3wrfA:14.08"]]