SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 LEU A 249
MET A 175
LEU A 235
MET A 185
THR A 256
 None
 1.40A 1a28A-3wrtA:
undetectable		 1a28A-3wrtA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 LEU A 249
MET A 175
LEU A 235
MET A 185
THR A 256
 None
 1.37A 1a28B-3wrtA:
undetectable		 1a28B-3wrtA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 7 ASN A 297
THR A 267
GLY A 264
ASP A 265
 None
 0.95A 1bu5A-3wrtA:
undetectable		 1bu5A-3wrtA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_B_RBFB302_1
(PROTEIN (FLAVODOXIN))		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 8 ASN A 297
THR A 267
GLY A 264
ASP A 265
 None
 0.91A 1bu5B-3wrtA:
undetectable		 1bu5B-3wrtA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 PRO A 141
LEU A 118
LEU A 218
LEU A 132
MET A 133
 None
 1.36A 1e7wA-3wrtA:
undetectable		 1e7wA-3wrtA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 10 LEU A  77
ALA A  78
GLU A  81
LEU A 167
LEU A 159
 None
 1.19A 1gwrA-3wrtA:
undetectable		 1gwrA-3wrtA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KVL_A_CLSA371_1
(BETA-LACTAMASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		7 / 10 LEU A 120
TYR A 151
ASN A 153
TYR A 223
LYS A 316
THR A 317
GLY A 318
 None
 0.35A 1kvlA-3wrtA:
53.2		 1kvlA-3wrtA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 6 LEU A  84
LEU A 270
ILE A 156
GLU A 162
 None
 1.05A 1mt1A-3wrtA:
undetectable
1mt1F-3wrtA:
undetectable		 1mt1A-3wrtA:
10.91
1mt1F-3wrtA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 7 LEU A  84
LEU A 270
ILE A 156
GLU A 162
 None
 1.01A 1n13I-3wrtA:
undetectable
1n13L-3wrtA:
undetectable		 1n13I-3wrtA:
10.91
1n13L-3wrtA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 THR A  59
ASN A 342
ILE A  26
LEU A  20
VAL A  17
 None
 1.01A 1r30A-3wrtA:
undetectable		 1r30A-3wrtA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_B_SAMB501_0
(BIOTIN SYNTHASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 THR A  59
ASN A 342
ILE A  26
LEU A  20
VAL A  17
 None
 1.01A 1r30B-3wrtA:
undetectable		 1r30B-3wrtA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 VAL A 314
ASN A 315
GLU A 273
LEU A  66
ILE A 327
 None
 1.13A 1t6zA-3wrtA:
undetectable		 1t6zA-3wrtA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 6 TYR A  93
ASP A  85
THR A 163
GLU A 162
 None
 1.35A 2dttB-3wrtA:
undetectable
2dttC-3wrtA:
undetectable		 2dttB-3wrtA:
16.29
2dttC-3wrtA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 6 LEU A 120
TYR A 151
ILE A 293
GLY A  64
 None
 0.78A 2du8A-3wrtA:
undetectable		 2du8A-3wrtA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 6 LEU A 120
TYR A 151
ILE A 293
GLY A  64
 None
 0.76A 2du8B-3wrtA:
undetectable		 2du8B-3wrtA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 ILE A 105
GLU A 162
GLY A 111
THR A 112
GLY A 115
 None
 1.45A 2fn1B-3wrtA:
undetectable		 2fn1B-3wrtA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_A_SAMA301_0
(YCGJ)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 GLY A 107
HIS A 113
THR A 114
THR A 163
ALA A  88
 None
 0.97A 2gluA-3wrtA:
undetectable		 2gluA-3wrtA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 GLY A 107
HIS A 113
THR A 114
THR A 163
ALA A  88
 None
 0.92A 2gluB-3wrtA:
undetectable		 2gluB-3wrtA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 MET A 339
LEU A 358
LEU A 284
PRO A 281
VAL A 279
 None
 1.32A 2po5B-3wrtA:
undetectable		 2po5B-3wrtA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		3 / 3 LEU A 118
PRO A 119
LEU A 154
 None
 0.42A 2qd5B-3wrtA:
undetectable		 2qd5B-3wrtA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YME_H_CWBH1207_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 TYR A 136
TRP A 135
SER A 152
THR A 142
TRP A 139
 None
 1.34A 2ymeH-3wrtA:
0.0
2ymeI-3wrtA:
0.0		 2ymeH-3wrtA:
21.23
2ymeI-3wrtA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXZ_A_ADNA401_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 LEU A  66
SER A  65
SER A  67
GLY A 324
GLY A 325
 None
 1.01A 3axzA-3wrtA:
undetectable		 3axzA-3wrtA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 LYS A  68
ASN A 153
LYS A 316
THR A 317
GLY A 318
 None
 0.60A 3huoA-3wrtA:
15.6		 3huoA-3wrtA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		6 / 12 SER A  65
LYS A  68
ASN A 153
GLY A 318
THR A 320
ARG A 350
 None
 1.11A 3mzeA-3wrtA:
14.3		 3mzeA-3wrtA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MZE_A_CFXA364_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACA)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		6 / 12 SER A  65
LYS A  68
ASN A 153
THR A 317
GLY A 318
THR A 320
 None
 0.78A 3mzeA-3wrtA:
14.3		 3mzeA-3wrtA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 GLU A 221
GLY A 224
ALA A 222
ILE A  63
ASP A 219
 None
 1.21A 3nmuB-3wrtA:
undetectable
3nmuJ-3wrtA:
undetectable		 3nmuB-3wrtA:
23.80
3nmuJ-3wrtA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 6 LEU A  77
LEU A  74
PRO A 182
LEU A 180
 None
 0.84A 3q1eA-3wrtA:
undetectable
3q1eC-3wrtA:
undetectable		 3q1eA-3wrtA:
17.45
3q1eC-3wrtA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 6 PRO A 182
LEU A 180
LEU A  77
LEU A  74
 None
 0.92A 3q1eA-3wrtA:
undetectable
3q1eC-3wrtA:
undetectable		 3q1eA-3wrtA:
17.45
3q1eC-3wrtA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 5 LEU A 340
LEU A  66
GLY A  64
GLY A 318
 None
 0.75A 3si7C-3wrtA:
undetectable
3si7D-3wrtA:
undetectable		 3si7C-3wrtA:
21.74
3si7D-3wrtA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		3 / 3 LEU A 118
PRO A 119
LEU A 154
 None
 0.38A 3w1wB-3wrtA:
undetectable		 3w1wB-3wrtA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 5 LEU A 232
LEU A 235
MET A 329
THR A  69
 None
 1.50A 4do3A-3wrtA:
undetectable		 4do3A-3wrtA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_486A303_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 9 THR A 163
LEU A  84
ALA A  75
LEU A 108
PHE A  86
 None
 1.39A 4ltwA-3wrtA:
undetectable		 4ltwA-3wrtA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 7 THR A 317
GLN A 268
ARG A 149
ILE A 293
 None
 0.92A 4txnA-3wrtA:
undetectable		 4txnA-3wrtA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 7 THR A 317
GLN A 268
ARG A 149
ILE A 293
 None
 0.90A 4txnB-3wrtA:
undetectable		 4txnB-3wrtA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 7 THR A 317
GLN A 268
ARG A 149
ILE A 293
 None
 0.96A 4txnC-3wrtA:
undetectable		 4txnC-3wrtA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 7 THR A 317
GLN A 268
ARG A 149
ILE A 293
 None
 0.93A 4txnD-3wrtA:
undetectable		 4txnD-3wrtA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 5 LEU A  13
ASP A  14
LEU A 361
THR A  40
 None
 1.16A 4wozF-3wrtA:
undetectable
4wozH-3wrtA:
undetectable		 4wozF-3wrtA:
22.31
4wozH-3wrtA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 ALA A 165
GLY A 169
LEU A 158
LEU A 159
THR A  71
 None
 1.17A 4zmeA-3wrtA:
undetectable		 4zmeA-3wrtA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 10 ALA A  78
GLU A  81
LEU A 167
GLY A 160
LEU A 159
 None
 1.35A 5dx3A-3wrtA:
undetectable		 5dx3A-3wrtA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 10 LEU A  77
ALA A  78
GLU A  81
LEU A 167
LEU A 159
 None
 1.24A 5dx3A-3wrtA:
undetectable		 5dx3A-3wrtA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 10 ALA A  78
GLU A  81
LEU A 167
GLY A 160
LEU A 159
 None
 1.35A 5dxbA-3wrtA:
undetectable		 5dxbA-3wrtA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 LEU A  77
ALA A  78
GLU A  81
LEU A 167
LEU A 159
 None
 1.24A 5dxgB-3wrtA:
undetectable		 5dxgB-3wrtA:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		4 / 4 LEU A 132
LEU A 158
GLY A 157
GLU A 221
 None
 1.08A 5hhjA-3wrtA:
undetectable		 5hhjA-3wrtA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 11 LEU A  77
ALA A  78
GLU A  81
LEU A 167
LEU A 159
 None
 1.23A 5hyrB-3wrtA:
undetectable		 5hyrB-3wrtA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		3 / 3 VAL A 245
LYS A 178
MET A 175
 None
 0.94A 5nknA-3wrtA:
undetectable		 5nknA-3wrtA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 9 ALA A  78
GLU A  81
LEU A 167
GLY A 160
LEU A 159
 None
 1.28A 5wgqA-3wrtA:
undetectable		 5wgqA-3wrtA:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 12 LEU A 361
ALA A 363
LEU A  33
THR A  39
LEU A 240
 None
 0.79A 6b0cD-3wrtA:
undetectable		 6b0cD-3wrtA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 3wrt BETA-LACTAMASE
(Chromohalobacter
sp.
560) 		5 / 10 LEU A  77
ALA A  78
GLU A  81
LEU A 167
LEU A 159
 None
 1.28A 6cbzB-3wrtA:
undetectable		 6cbzB-3wrtA:
15.38