SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wrv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 10 PHE A 106
VAL A  51
VAL A  53
ILE A  96
LEU A 131
 None
 1.27A 1fe2A-3wrvA:
undetectable		 1fe2A-3wrvA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 ASP A 163
SER A 162
LEU A 103
ILE A  14
PHE A 167
 None
 1.40A 3ko0A-3wrvA:
undetectable
3ko0B-3wrvA:
undetectable
3ko0C-3wrvA:
undetectable
3ko0D-3wrvA:
undetectable		 3ko0A-3wrvA:
20.00
3ko0B-3wrvA:
20.00
3ko0C-3wrvA:
20.00
3ko0D-3wrvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 ASP A 163
SER A 162
LEU A 107
ILE A  14
PHE A 167
 None
 1.35A 3ko0A-3wrvA:
undetectable
3ko0B-3wrvA:
undetectable
3ko0C-3wrvA:
undetectable
3ko0D-3wrvA:
undetectable		 3ko0A-3wrvA:
20.00
3ko0B-3wrvA:
20.00
3ko0C-3wrvA:
20.00
3ko0D-3wrvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 ASP A 163
SER A 162
LEU A 103
ILE A  14
PHE A 167
 None
 1.44A 3ko0K-3wrvA:
undetectable
3ko0L-3wrvA:
undetectable
3ko0M-3wrvA:
undetectable
3ko0N-3wrvA:
undetectable		 3ko0K-3wrvA:
20.00
3ko0L-3wrvA:
20.00
3ko0M-3wrvA:
20.00
3ko0N-3wrvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 ASP A 163
SER A 162
LEU A 107
ILE A  14
PHE A 167
 None
 1.28A 3ko0K-3wrvA:
undetectable
3ko0L-3wrvA:
undetectable
3ko0M-3wrvA:
undetectable
3ko0N-3wrvA:
undetectable		 3ko0K-3wrvA:
20.00
3ko0L-3wrvA:
20.00
3ko0M-3wrvA:
20.00
3ko0N-3wrvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 LEU A 103
ILE A  14
PHE A 167
ASP A 163
SER A 162
 None
 1.33A 3ko0O-3wrvA:
undetectable
3ko0P-3wrvA:
undetectable
3ko0Q-3wrvA:
undetectable
3ko0R-3wrvA:
undetectable		 3ko0O-3wrvA:
20.00
3ko0P-3wrvA:
20.00
3ko0Q-3wrvA:
20.00
3ko0R-3wrvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 LEU A 107
ILE A  14
PHE A 167
ASP A 163
SER A 162
 None
 1.39A 3ko0O-3wrvA:
undetectable
3ko0P-3wrvA:
undetectable
3ko0Q-3wrvA:
undetectable
3ko0R-3wrvA:
undetectable		 3ko0O-3wrvA:
20.00
3ko0P-3wrvA:
20.00
3ko0Q-3wrvA:
20.00
3ko0R-3wrvA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 4 SER A  71
SER A  56
THR A  55
SER A  54
 None
 1.16A 3loqA-3wrvA:
3.5		 3loqA-3wrvA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 ASP A  18
SER A 132
ILE A 146
THR A  19
ALA A  97
 None
 1.36A 3ua1A-3wrvA:
undetectable		 3ua1A-3wrvA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 ALA A 187
ILE A 120
VAL A  31
PRO A 143
VAL A 145
 None
 0.97A 3ucbB-3wrvA:
undetectable		 3ucbB-3wrvA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1004_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 ALA A 134
LEU A 103
GLY A  15
PHE A  66
GLY A 121
 None
 0.91A 3zosA-3wrvA:
undetectable
3zosB-3wrvA:
undetectable		 3zosA-3wrvA:
22.48
3zosB-3wrvA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 4 LEU A 116
ILE A  14
GLY A 118
PHE A 135
 None
 0.87A 4dc3A-3wrvA:
6.4		 4dc3A-3wrvA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 10 ALA A 187
ILE A 120
VAL A  31
PRO A 143
VAL A 145
 None
 0.97A 4j5jB-3wrvA:
undetectable		 4j5jB-3wrvA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 VAL A 119
ALA A 117
PHE A 191
 None
 0.70A 4olbA-3wrvA:
3.9		 4olbA-3wrvA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 VAL A 195
VAL A  31
ILE A 120
GLY A 121
LEU A 107
 None
 0.95A 4y8wA-3wrvA:
undetectable		 4y8wA-3wrvA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 VAL A 195
VAL A  31
ILE A 120
GLY A 121
LEU A 107
 None
 0.99A 4y8wB-3wrvA:
undetectable		 4y8wB-3wrvA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 VAL A 195
VAL A  31
ILE A 120
GLY A 121
LEU A 107
 None
 0.96A 4y8wC-3wrvA:
undetectable		 4y8wC-3wrvA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 VAL A 119
ALA A 117
PHE A 191
 None
 0.72A 4z4iA-3wrvA:
4.8		 4z4iA-3wrvA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 LEU A 103
GLY A 121
VAL A  53
PHE A 191
GLY A  47
 None
 1.03A 5f9zA-3wrvA:
4.2		 5f9zA-3wrvA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 VAL A 119
ALA A 117
PHE A 191
 None
 0.69A 5js1A-3wrvA:
undetectable		 5js1A-3wrvA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 7 LEU A 138
ALA A 134
ILE A 146
LEU A 164
 None
 0.95A 5te8A-3wrvA:
undetectable		 5te8A-3wrvA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3wrv TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 4 LEU A 122
GLY A 123
SER A 148
SER A 169
 None
 1.26A 5uunA-3wrvA:
undetectable		 5uunA-3wrvA:
20.41