SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wry'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 PHE A 417
LEU A 266
SER A 424
 None
 0.86A 1e7aA-3wryA:
undetectable		 1e7aA-3wryA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 PHE A 349
ARG A 251
VAL A 265
LEU A 354
ILE A 350
 None
 1.08A 1kqwA-3wryA:
undetectable		 1kqwA-3wryA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 GLU A 367
LYS A 406
VAL A 407
 None
 0.95A 1l2iA-3wryA:
undetectable		 1l2iA-3wryA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 GLY A 118
GLY A 141
ASP A 163
ILE A 140
VAL A 195
 None
 1.03A 1pg2A-3wryA:
3.2		 1pg2A-3wryA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 6 ASP A 255
LEU A 256
VAL A 257
ILE A 262
 None
 1.02A 1s9qA-3wryA:
undetectable		 1s9qA-3wryA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 7 LEU A 393
PHE A 417
VAL A 422
SER A 424
 None
 1.06A 1wrlA-3wryA:
undetectable
1wrlB-3wryA:
undetectable		 1wrlA-3wryA:
11.42
1wrlB-3wryA:
11.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJF_B_ADNB2002_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 6 ARG A 288
GLU A 352
ASN A 400
ALA A 357
 None
 1.40A 2ejfB-3wryA:
undetectable		 2ejfB-3wryA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI9_X_SAMX501_0
(UPF0217 PROTEIN
MJ1640)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 9 LEU A 184
GLY A 175
LEU A  27
SER A  28
LEU A  24
 None
 1.09A 3ai9X-3wryA:
3.0		 3ai9X-3wryA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 LEU A 107
ILE A  14
PHE A 167
ASP A 163
SER A 162
 None
 1.36A 3ko0C-3wryA:
undetectable
3ko0D-3wryA:
undetectable
3ko0E-3wryA:
undetectable
3ko0F-3wryA:
undetectable		 3ko0C-3wryA:
12.53
3ko0D-3wryA:
12.53
3ko0E-3wryA:
12.53
3ko0F-3wryA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 LEU A 107
ILE A  14
PHE A 167
ASP A 163
SER A 162
 None
 1.37A 3ko0G-3wryA:
undetectable
3ko0H-3wryA:
undetectable
3ko0I-3wryA:
undetectable
3ko0J-3wryA:
undetectable		 3ko0G-3wryA:
12.53
3ko0H-3wryA:
12.53
3ko0I-3wryA:
12.53
3ko0J-3wryA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 11 ASP A 163
SER A 162
LEU A 107
ILE A  14
PHE A 167
 None
 1.43A 3ko0Q-3wryA:
undetectable
3ko0R-3wryA:
undetectable
3ko0S-3wryA:
undetectable
3ko0T-3wryA:
undetectable		 3ko0Q-3wryA:
12.53
3ko0R-3wryA:
12.53
3ko0S-3wryA:
12.53
3ko0T-3wryA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 LEU A 122
GLY A 188
ALA A 187
ILE A 173
ILE A 147
 None
 0.77A 3s54A-3wryA:
undetectable		 3s54A-3wryA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 ASP A  18
SER A 132
ILE A 146
THR A  19
ALA A  97
 AGS  A 501 (-2.6A)
None
None
AGS  A 501 (-3.2A)
None
 1.29A 3ua1A-3wryA:
undetectable		 3ua1A-3wryA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 ALA A 187
ILE A 120
VAL A  31
PRO A 143
VAL A 145
 None
 0.92A 3ucbB-3wryA:
undetectable		 3ucbB-3wryA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 6 GLY A 264
ARG A 258
ILE A 262
LEU A 266
 None
 1.00A 4ac9C-3wryA:
5.4		 4ac9C-3wryA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 6 GLY A 264
ARG A 258
ILE A 262
LEU A 266
 None
 1.05A 4acaC-3wryA:
5.1		 4acaC-3wryA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 6 GLY A 264
ARG A 258
ILE A 262
LEU A 266
 None
 1.03A 4acbC-3wryA:
5.2		 4acbC-3wryA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 4 LEU A 116
ILE A  14
GLY A 118
PHE A 135
 None
 0.85A 4dc3A-3wryA:
3.8		 4dc3A-3wryA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 10 ALA A 187
ILE A 120
VAL A  31
PRO A 143
VAL A 145
 None
 0.95A 4j5jB-3wryA:
undetectable		 4j5jB-3wryA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLB_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 VAL A 119
ALA A 117
PHE A 191
 None
 0.64A 4olbA-3wryA:
3.8		 4olbA-3wryA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 VAL A 195
VAL A  31
ILE A 120
GLY A 121
LEU A 107
 None
 1.06A 4y8wA-3wryA:
undetectable		 4y8wA-3wryA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 VAL A 195
VAL A  31
ILE A 120
GLY A 121
LEU A 107
 None
 1.10A 4y8wB-3wryA:
undetectable		 4y8wB-3wryA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 VAL A 119
ALA A 117
PHE A 191
 None
 0.66A 4z4iA-3wryA:
2.1		 4z4iA-3wryA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 LEU A 122
GLY A 188
ALA A 187
ILE A 173
ILE A 147
 None
 0.81A 5e5jB-3wryA:
undetectable		 5e5jB-3wryA:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 LEU A 103
GLY A 121
VAL A  53
PHE A 191
GLY A  47
 None
 1.09A 5f9zA-3wryA:
3.4		 5f9zA-3wryA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		3 / 3 VAL A 119
ALA A 117
PHE A 191
 None
 0.63A 5js1A-3wryA:
undetectable		 5js1A-3wryA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 5 SER A 371
VAL A 370
GLY A 304
ALA A 305
 None
 0.96A 5k50A-3wryA:
4.0		 5k50A-3wryA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		4 / 4 LEU A 122
GLY A 123
SER A 148
SER A 169
 None
AGS  A 501 ( 4.1A)
None
None
 1.36A 5uunA-3wryA:
undetectable		 5uunA-3wryA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_C_HISC402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 9 VAL A 229
VAL A 300
LEU A 233
GLY A 264
VAL A 216
 None
 1.36A 6czmB-3wryA:
1.5
6czmC-3wryA:
undetectable		 6czmB-3wryA:
24.45
6czmC-3wryA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 3wry TM-1 PROTEIN
(Solanum
lycopersicum) 		5 / 12 LEU A 122
GLY A 188
ALA A 187
ILE A 173
ILE A 147
 None
 0.79A 6dh3A-3wryA:
undetectable		 6dh3A-3wryA:
10.21