SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 6 SER A 172
VAL A 230
GLY A 229
LEU A 134
 None
 0.92A 1fduD-3wsoA:
undetectable		 1fduD-3wsoA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 6 PHE A 126
GLU A 107
LEU A 109
VAL A 122
 None
 1.04A 1hk1A-3wsoA:
undetectable		 1hk1A-3wsoA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 4 HIS A 211
VAL A 160
THR A 190
LEU A 181
 None
 1.21A 1oq5A-3wsoA:
undetectable		 1oq5A-3wsoA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 8 ASP A 162
PHE A 225
LEU A  82
TRP A  94
 None
 1.03A 1rmtD-3wsoA:
undetectable		 1rmtD-3wsoA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_A_SAMA801_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 10 GLU A  89
GLY A  90
SER A  95
ASN A  84
HIS A  83
 None
 1.35A 2h21A-3wsoA:
undetectable		 2h21A-3wsoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_B_SAMB802_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 11 GLU A  89
GLY A  90
SER A  95
ASN A  84
HIS A  83
 None
 1.28A 2h21B-3wsoA:
undetectable		 2h21B-3wsoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H21_C_SAMC803_0
(RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 11 GLU A  89
GLY A  90
SER A  95
ASN A  84
HIS A  83
 None
 1.31A 2h21C-3wsoA:
undetectable		 2h21C-3wsoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBV_A_ADNA501_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 10 ASP A 162
TRP A 163
VAL A 122
ASN A  80
ASN A  84
 None
 1.38A 2zbvA-3wsoA:
0.0
2zbvB-3wsoA:
0.0		 2zbvA-3wsoA:
20.00
2zbvB-3wsoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBV_B_ADNB502_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 10 ASP A 162
TRP A 163
VAL A 122
ASN A  80
ASN A  84
 None
 1.38A 2zbvB-3wsoA:
0.0
2zbvC-3wsoA:
0.0		 2zbvB-3wsoA:
20.00
2zbvC-3wsoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBV_C_ADNC503_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 9 ASN A  80
ASN A  84
ASP A 162
TRP A 163
VAL A 122
 None
 1.41A 2zbvA-3wsoA:
0.0
2zbvC-3wsoA:
0.0		 2zbvA-3wsoA:
20.00
2zbvC-3wsoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 4 PRO A 217
TYR A 216
GLY A 189
THR A 190
 None
 1.45A 3ib0A-3wsoA:
undetectable		 3ib0A-3wsoA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 7 TYR A 125
TRP A 206
CYH A 170
TYR A 239
 None
 1.29A 3pmzE-3wsoA:
0.0		 3pmzE-3wsoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		5 / 7 GLY A 219
PRO A 217
TYR A 216
GLY A 189
THR A 190
 None
 1.42A 3tajA-3wsoA:
undetectable		 3tajA-3wsoA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 4 VAL A 178
ILE A 158
ASN A  80
VAL A 139
 None
 1.31A 5ajqA-3wsoA:
0.5		 5ajqA-3wsoA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 5 TYR A 216
MET A 151
THR A 153
LEU A 150
 None
 1.24A 5x1fW-3wsoA:
undetectable		 5x1fW-3wsoA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 5 TYR A 216
MET A 151
THR A 153
LEU A 150
 None
 1.29A 6nknJ-3wsoA:
undetectable		 6nknJ-3wsoA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3wso F-BOX ONLY PROTEIN
44
(Homo
sapiens) 		4 / 5 TYR A 216
MET A 151
THR A 153
LEU A 150
 None
 1.30A 6nknW-3wsoA:
undetectable		 6nknW-3wsoA:
13.33