SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wtd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3wtd UNCHARACTERIZED
PROTEIN C9ORF142
(Homo
sapiens) 		4 / 6 ARG A  63
ASP A 108
VAL A  85
ALA A  86
 None
 0.87A 4nkxA-3wtdA:
undetectable		 4nkxA-3wtdA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 3wtd UNCHARACTERIZED
PROTEIN C9ORF142
(Homo
sapiens) 		5 / 12 LEU A  98
GLU A  81
THR A  73
ARG A  77
GLU A  27
 None
 1.29A 4q15B-3wtdA:
undetectable		 4q15B-3wtdA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_D_HFGD1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 3wtd UNCHARACTERIZED
PROTEIN C9ORF142
(Homo
sapiens) 		5 / 12 LEU A  98
GLU A  81
THR A  73
ARG A  77
GLU A  27
 None
 1.30A 5xipD-3wtdA:
undetectable		 5xipD-3wtdA:
15.46