SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wtr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3wtr UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		5 / 11 ILE A  58
PHE A 108
TYR A  54
HIS A   5
PHE A 157
 None
 1.18A 2dg4A-3wtrA:
undetectable		 2dg4A-3wtrA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 3wtr UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 THR A  24
PRO A  37
TYR A  35
 None
 0.89A 2dxrA-3wtrA:
undetectable		 2dxrA-3wtrA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 3wtr UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 6 LEU A 161
TYR A 165
ILE A  58
ILE A  13
 None
 0.94A 2q8hA-3wtrA:
undetectable		 2q8hA-3wtrA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_A_DAHA60_1
(PUTATIVE CYTOCHROME
C)		 3wtr UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 6 HIS A   5
VAL A 110
LEU A 161
GLN A 174
 None
 1.34A 5xdhA-3wtrA:
undetectable
5xdhC-3wtrA:
undetectable		 5xdhA-3wtrA:
17.58
5xdhC-3wtrA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 3wtr UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 6 GLN A 174
HIS A   5
VAL A 110
LEU A 161
 None
 1.30A 5xdhA-3wtrA:
undetectable
5xdhC-3wtrA:
undetectable		 5xdhA-3wtrA:
17.58
5xdhC-3wtrA:
17.58