SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wu1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		3 / 3 PHE B 363
ASP B 359
ARG B 413
 None
 0.60A 4eahF-3wu1B:
undetectable		 4eahF-3wu1B:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		3 / 3 PHE B 363
ASP B 359
ARG B 413
 None
 0.59A 4eahG-3wu1B:
undetectable		 4eahG-3wu1B:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		4 / 7 SER B 390
TYR B 412
GLU B 387
PRO B 368
 None
 1.01A 5aclA-3wu1B:
undetectable		 5aclA-3wu1B:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		4 / 6 VAL B 435
HIS B 430
LEU B 433
LEU B 345
 None
 1.26A 5hrqB-3wu1B:
undetectable
5hrqI-3wu1B:
undetectable
5hrqJ-3wu1B:
undetectable		 5hrqB-3wu1B:
14.02
5hrqI-3wu1B:
9.17
5hrqJ-3wu1B:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		5 / 12 GLY B 376
GLN B 339
LEU B 341
GLU B 343
LEU B 344
 None
 0.95A 5nwwA-3wu1B:
undetectable		 5nwwA-3wu1B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		5 / 12 GLY B 376
GLN B 339
LEU B 342
GLU B 343
LEU B 344
 None
 1.11A 5nwwA-3wu1B:
undetectable		 5nwwA-3wu1B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_D_AM2D301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3wu1 PROTEIN C-ETS-1
(Homo
sapiens) 		4 / 8 ARG B 413
HIS B 403
GLU B 362
ASP B 359
 None
 0.92A 6mn4D-3wu1B:
undetectable		 6mn4D-3wu1B:
16.41