SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wv6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 8 PHE A  93
VAL A  47
VAL A 120
VAL A 112
 None
 0.91A 1iwiA-3wv6A:
undetectable		 1iwiA-3wv6A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 12 PHE A 222
LEU A 236
PHE A 295
VAL A 245
ALA A 288
 None
 1.24A 1q23H-3wv6A:
undetectable
1q23I-3wv6A:
undetectable		 1q23H-3wv6A:
20.20
1q23I-3wv6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 11 PHE A 119
LEU A 142
VAL A 140
PHE A  99
VAL A  33
 None
 1.43A 1q23J-3wv6A:
undetectable		 1q23J-3wv6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 9 LEU A 203
LEU A 226
VAL A 287
ALA A 288
LEU A  11
 None
 1.09A 1tbfA-3wv6A:
undetectable		 1tbfA-3wv6A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 6 HIS A  61
ASN A  63
ARG A  44
TRP A  82
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
GAL  A 402 ( 4.9A)
GAL  A 402 (-3.7A)
 1.09A 3galA-3wv6A:
22.8		 3galA-3wv6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3wv6 GALECTIN-9
(Homo
sapiens) 		6 / 6 HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
 0.20A 3galA-3wv6A:
22.8		 3galA-3wv6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 3wv6 GALECTIN-9
(Homo
sapiens) 		6 / 6 HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
 GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
 0.20A 3galA-3wv6A:
22.8		 3galA-3wv6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3wv6 GALECTIN-9
(Homo
sapiens) 		6 / 6 HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
 0.38A 3galB-3wv6A:
22.7		 3galB-3wv6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 3wv6 GALECTIN-9
(Homo
sapiens) 		6 / 6 HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
 GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
 0.36A 3galB-3wv6A:
22.7		 3galB-3wv6A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_H_CLMH221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 12 LEU A  25
VAL A 105
PHE A 110
VAL A 131
PHE A 147
 None
 1.46A 3u9fH-3wv6A:
undetectable
3u9fI-3wv6A:
undetectable		 3u9fH-3wv6A:
20.20
3u9fI-3wv6A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 11 LEU A 101
ILE A 134
VAL A  47
PHE A  45
VAL A  15
 None
 1.09A 3w67A-3wv6A:
undetectable		 3w67A-3wv6A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 12 LEU A 101
ILE A 134
VAL A  47
PHE A  45
VAL A  15
 None
 1.13A 3w68A-3wv6A:
undetectable		 3w68A-3wv6A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 12 VAL A  72
PHE A  60
PHE A  62
LEU A 101
VAL A  33
 None
 1.21A 4eckA-3wv6A:
undetectable		 4eckA-3wv6A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 7 ARG A  44
VAL A  73
GLU A  85
ARG A  87
 GAL  A 402 ( 4.9A)
None
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
 1.32A 4mv7A-3wv6A:
undetectable		 4mv7A-3wv6A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 4 ASN A  63
SER A 139
ALA A  46
VAL A  47
 GAL  A 402 (-3.9A)
None
None
None
 0.98A 4x1kC-3wv6A:
undetectable		 4x1kC-3wv6A:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 8 LEU A 318
THR A 323
THR A 197
LEU A 310
 None
 0.71A 4z90F-3wv6A:
undetectable
4z90G-3wv6A:
undetectable
4z90H-3wv6A:
undetectable
4z90I-3wv6A:
undetectable
4z90J-3wv6A:
undetectable		 4z90F-3wv6A:
22.54
4z90G-3wv6A:
22.54
4z90H-3wv6A:
22.54
4z90I-3wv6A:
22.54
4z90J-3wv6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 7 LEU A 318
THR A 323
THR A 197
LEU A 310
 None
 0.72A 4z91F-3wv6A:
undetectable
4z91G-3wv6A:
undetectable
4z91H-3wv6A:
undetectable
4z91I-3wv6A:
undetectable
4z91J-3wv6A:
undetectable		 4z91F-3wv6A:
22.54
4z91G-3wv6A:
22.54
4z91H-3wv6A:
22.54
4z91I-3wv6A:
22.54
4z91J-3wv6A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 3wv6 GALECTIN-9
(Homo
sapiens) 		5 / 9 HIS A 188
HIS A 320
TYR A 144
ASN A  34
THR A 319
 ZN  A 401 (-3.2A)
ZN  A 401 (-3.2A)
None
EDO  A 407 (-3.5A)
EDO  A 406 ( 3.0A)
 1.46A 5m8nC-3wv6A:
undetectable		 5m8nC-3wv6A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 4 ASN A  63
SER A 139
ALA A  46
VAL A  47
 GAL  A 402 (-3.9A)
None
None
None
 0.86A 5nm5A-3wv6A:
undetectable		 5nm5A-3wv6A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 6 PHE A  45
LEU A  38
ARG A  44
GLY A  42
 None
None
GAL  A 402 ( 4.9A)
None
 0.75A 5o4yA-3wv6A:
undetectable		 5o4yA-3wv6A:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 6 PHE A  45
LEU A  38
ARG A  44
GLY A  42
 None
None
GAL  A 402 ( 4.9A)
None
 0.69A 5o4yF-3wv6A:
undetectable		 5o4yF-3wv6A:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 7 HIS A  61
ASN A  63
ARG A  44
TRP A  82
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
GAL  A 402 ( 4.9A)
GAL  A 402 (-3.7A)
 1.11A 6b8kA-3wv6A:
23.7		 6b8kA-3wv6A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3wv6 GALECTIN-9
(Homo
sapiens) 		7 / 7 HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
 0.37A 6b8kA-3wv6A:
23.7		 6b8kA-3wv6A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 3wv6 GALECTIN-9
(Homo
sapiens) 		7 / 7 HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
 GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
 0.24A 6b8kA-3wv6A:
23.7		 6b8kA-3wv6A:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 8 HIS A  61
ASN A  63
ARG A  44
TRP A  82
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
GAL  A 402 ( 4.9A)
GAL  A 402 (-3.7A)
 1.04A 6b94A-3wv6A:
19.4		 6b94A-3wv6A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		7 / 8 HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
 0.38A 6b94A-3wv6A:
19.4		 6b94A-3wv6A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		7 / 8 HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
 GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
 0.54A 6b94A-3wv6A:
19.4		 6b94A-3wv6A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		7 / 10 HIS A  61
ASN A  63
ARG A  65
ASN A  75
TRP A  82
GLU A  85
ARG A  87
 GAL  A 402 (-3.9A)
GAL  A 402 (-3.9A)
BGC  A 403 (-2.7A)
GAL  A 402 (-4.0A)
GAL  A 402 (-3.7A)
BGC  A 403 (-2.9A)
BGC  A 403 (-4.1A)
 0.46A 6b94A-3wv6A:
19.4
6b94B-3wv6A:
19.1		 6b94A-3wv6A:
12.93
6b94B-3wv6A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 3wv6 GALECTIN-9
(Homo
sapiens) 		7 / 10 HIS A 235
ASN A 237
ARG A 239
ASN A 248
TRP A 255
GLU A 258
ARG A 260
 GAL  A 404 (-4.0A)
GAL  A 404 (-4.1A)
GLC  A 405 (-2.7A)
GAL  A 404 (-3.7A)
GAL  A 404 ( 3.7A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
 0.44A 6b94A-3wv6A:
19.4
6b94B-3wv6A:
19.1		 6b94A-3wv6A:
12.93
6b94B-3wv6A:
12.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FK2_A_SORA302_0
(GALECTIN-3)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 4 ARG A 239
GLU A 242
GLU A 258
ARG A 260
 GLC  A 405 (-2.7A)
GLC  A 405 ( 4.8A)
GLC  A 405 ( 2.8A)
GLC  A 405 (-4.3A)
 0.63A 6fk2A-3wv6A:
23.9		 6fk2A-3wv6A:
30.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6FK2_A_SORA302_0
(GALECTIN-3)		 3wv6 GALECTIN-9
(Homo
sapiens) 		4 / 4 ARG A 260
GLU A 258
GLU A 242
ARG A 239
 GLC  A 405 (-4.3A)
GLC  A 405 ( 2.8A)
GLC  A 405 ( 4.8A)
GLC  A 405 (-2.7A)
 1.05A 6fk2A-3wv6A:
23.9		 6fk2A-3wv6A:
30.09