SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3wvl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.30A 3fhjA-3wvlO:
undetectable		 3fhjA-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.29A 3fhjB-3wvlO:
undetectable		 3fhjB-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.29A 3fhjC-3wvlO:
undetectable		 3fhjC-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.30A 3fhjD-3wvlO:
undetectable		 3fhjD-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 10 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.30A 3fhjE-3wvlO:
undetectable		 3fhjE-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FHJ_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.30A 3fhjF-3wvlO:
undetectable		 3fhjF-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_A_TRPA1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.35A 3fi0A-3wvlO:
undetectable		 3fi0A-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_C_TRPC1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.31A 3fi0C-3wvlO:
undetectable		 3fi0C-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_D_TRPD1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.32A 3fi0D-3wvlO:
undetectable		 3fi0D-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_F_TRPF1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.38A 3fi0F-3wvlO:
undetectable		 3fi0F-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_H_TRPH1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.33A 3fi0H-3wvlO:
undetectable		 3fi0H-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_J_TRPJ1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.34A 3fi0J-3wvlO:
undetectable		 3fi0J-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_K_TRPK1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.26A 3fi0K-3wvlO:
undetectable		 3fi0K-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.37A 3fi0L-3wvlO:
undetectable		 3fi0L-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_M_TRPM1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.28A 3fi0M-3wvlO:
undetectable		 3fi0M-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_N_TRPN1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.37A 3fi0N-3wvlO:
undetectable		 3fi0N-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_O_TRPO1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.28A 3fi0O-3wvlO:
undetectable		 3fi0O-3wvlO:
16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_R_TRPR1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3wvl 10 KDA CHAPERONIN
(Escherichia
coli) 		5 / 9 VAL O  73
ASP O  90
ILE O  91
VAL O  65
VAL O  40
 None
 1.38A 3fi0R-3wvlO:
undetectable		 3fi0R-3wvlO:
16.41