SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ww0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3ww0 PROTEIN HIKESHI
(Homo
sapiens) 		4 / 8 LEU B 193
SER B 133
ASN B 129
ASP B 136
 None
 1.14A 1ig3A-3ww0B:
undetectable
1ig3B-3ww0B:
2.5		 1ig3A-3ww0B:
18.70
1ig3B-3ww0B:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3ww0 PROTEIN HIKESHI
(Homo
sapiens) 		4 / 7 ASP B 136
LEU B 193
SER B 133
ASN B 129
 None
 1.15A 1ig3A-3ww0B:
undetectable
1ig3B-3ww0B:
2.5		 1ig3A-3ww0B:
18.70
1ig3B-3ww0B:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3ww0 PROTEIN HIKESHI
(Homo
sapiens) 		4 / 6 LEU B 188
TRP B 195
LEU B 193
PHE B 138
 None
 1.31A 1ru9H-3ww0B:
2.6
1ru9L-3ww0B:
undetectable		 1ru9H-3ww0B:
26.32
1ru9L-3ww0B:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 3ww0 PROTEIN HIKESHI
(Homo
sapiens) 		4 / 6 LEU B 188
TRP B 195
LEU B 193
PHE B 138
 None
 1.30A 1rukH-3ww0B:
2.5
1rukL-3ww0B:
undetectable		 1rukH-3ww0B:
26.32
1rukL-3ww0B:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 3ww0 PROTEIN HIKESHI
(Homo
sapiens) 		4 / 7 GLN B  12
THR B  13
LEU B  41
THR B  74
 None
 1.07A 4mbsA-3ww0B:
undetectable		 4mbsA-3ww0B:
17.34